Literature DB >> 25154727

Diffusion-weighted MRI of the prostate: advantages of Zoomed EPI with parallel-transmit-accelerated 2D-selective excitation imaging.

Kolja M Thierfelder1, Michael K Scherr, Mike Notohamiprodjo, Jakob Weiß, Olaf Dietrich, Ullrich G Mueller-Lisse, Josef Pfeuffer, Konstantin Nikolaou, Daniel Theisen.   

Abstract

OBJECTIVES: The purpose of our study was to evaluate the use of 2D-selective, parallel-transmit excitation magnetic resonance imaging (MRI) for diffusion-weighted echo-planar imaging (pTX-EPI) of the prostate, and to compare it to conventional, single-shot EPI (c-EPI).
METHODS: The MRI examinations of 35 patients were evaluated in this prospective study. PTX-EPI was performed with a TX-acceleration factor of 1.7 and a field of view (FOV) of 150 × 90 mm(2), whereas c-EPI used a full FOV of 380 × 297 mm(2). Two readers evaluated three different aspects of image quality on 5-point Likert scales. To quantify distortion artefacts, maximum diameters and prostate volume were determined for both techniques and compared to T2-weighted imaging.
RESULTS: The zoomed pTX-EPI was superior to c-EPI with respect to overall image quality (3.39 ± 0.62 vs 2.45 ± 0.67) and anatomic differentiability (3.29 ± 0.65 vs 2.41 ± 0.65), each with p < 0.0001. Artefacts were significantly less severe in pTX-EPI (0.93 ± 0.73 vs 1.49 ± 1.08), p < 0.001. The quantitative analysis yielded a higher agreement of pTX-EPI with T2-weighted imaging than c-EPI with respect to coronal (ICCs: 0.95 vs 0.93) and sagittal (0.86 vs 0.73) diameters as well as prostate volume (0.94 vs 0.92). Apparent diffusion coefficient (ADC) values did not differ significantly between the two techniques (p > 0.05).
CONCLUSIONS: Zoomed pTX-EPI leads to substantial improvements in diffusion-weighted imaging (DWI) of the prostate with respect to different aspects of image quality and severity of artefacts. KEY POINTS: Recent technical developments in MRI allow the use of accelerated, spatially-selective excitation (parallel-transmit, pTX). pTX can be used for zoomed echo-planar prostate imaging (pTX-EPI). pTX-EPI improves different aspects of image quality in prostate MRI. Distortion artefacts are reduced by the use of pTX-EPI in prostate MRI. Further studies should aim at assessing the diagnostic accuracy of pTX-EPI.

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Year:  2014        PMID: 25154727     DOI: 10.1007/s00330-014-3347-y

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


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