Literature DB >> 3026173

Linkage of cystic fibrosis locus and polymorphic DNA markers in 14 families.

S L Naylor, D R Barnett, J M Buchanan, J Latimer, K Wieder, S Marshall, J Gardner, C R Denning, M Gluckson, R Pinero.   

Abstract

Linkage relationships between the cystic fibrosis (CF) locus and three polymorphic DNA markers were examined in 14 families, five of which were of Hispanic origin. Tight linkage was found between the CF locus and MET (maximum lod score = 7.16 at theta = .001), and between CF and pJ3.11 (maximum lod score = 3.87 at theta = .001). We observed two recombinations between CF and collagen, yielding a maximum lod score of 0.359 at theta = .125, and one recombination in the cluster CF-MET-pJ3.11. Analysis by the seriation method indicates the order COL-pJ3.11-CF-MET.

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Year:  1986        PMID： 3026173      PMCID： PMC1684117     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  18 in total

1.  Current concepts in genetics. Cystic fibrosis.

Authors:  B H Bowman; J A Mangos
Journal:  N Engl J Med       Date:  1976-04-22       Impact factor: 91.245

2.  Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Authors:  G M Wahl; M Stern; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

3.  Improved detection of the sickle mutation by DNA analysis: application to prenatal diagnosis.

Authors:  S H Orkin; P F Little; H H Kazazian; C D Boehm
Journal:  N Engl J Med       Date:  1982-07-01       Impact factor: 91.245

4.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

5.  A polymorphic DNA marker genetically linked to Huntington's disease.

Authors:  J F Gusella; N S Wexler; P M Conneally; S L Naylor; M A Anderson; R E Tanzi; P C Watkins; K Ottina; M R Wallace; A Y Sakaguchi
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

6.  Easy calculations of lod scores and genetic risks on small computers.

Authors:  G M Lathrop; J M Lalouel
Journal:  Am J Hum Genet       Date:  1984-03       Impact factor: 11.025

7.  Strategies for multilocus linkage analysis in humans.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

8.  Cystic fibrosis locus defined by a genetically linked polymorphic DNA marker.

Authors:  L C Tsui; M Buchwald; D Barker; J C Braman; R Knowlton; J W Schumm; H Eiberg; J Mohr; D Kennedy; N Plavsic
Journal:  Science       Date:  1985-11-29       Impact factor: 47.728

9.  Linkage relationships of paraoxonase (PON) with other markers: indication of PON-cystic fibrosis synteny.

Authors:  H Eiberg; J Mohr; K Schmiegelow; L S Nielsen; R Williamson
Journal:  Clin Genet       Date:  1985-10       Impact factor: 4.438

10.  Human immune interferon gene is located on chromosome 12.

Authors:  S L Naylor; A Y Sakaguchi; T B Shows; M L Law; D V Goeddel; P W Gray
Journal:  J Exp Med       Date:  1983-03-01       Impact factor: 14.307
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  5 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 6.

Authors:  R W Elliott; K J Moore
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 4.  Genetic markers on chromosome 7.

Authors:  L C Tsui
Journal:  J Med Genet       Date:  1988-05       Impact factor: 6.318

5.  Cystic fibrosis.

Authors:  I Harwood; F Rosas; D K Edwards; J Kelso; W L Nyhan
Journal:  West J Med       Date:  1988-01
  5 in total

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