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Literature DB >> 3010310

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

E B Leof, J A Proper, A S Goustin, G D Shipley, P E DiCorleto, H L Moses.

Abstract

Treatment of quiescent cultures of mouse embryo-derived AKR-2B cells with transforming growth factor beta resulted in an early induction of c-sis mRNA. The increase in c-sis mRNA was followed by a corresponding increase in protein similar to platelet-derived growth factor (PDGF) in the culture medium. In addition, PDGF-regulated genes (c-fos and c-myc) were stimulated by transforming growth factor beta with delayed kinetics relative to that seen in other cell systems with direct PDGF stimulation. A model is proposed in which the monolayer mitogenicity of transforming growth factor beta is mediated by the induction of c-sis and PDGF and the subsequent autocrine stimulation of c-fos, c-myc, and other PDGF-inducible genes.

Entities: Gene Species

Mesh：

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Year: 1986 PMID： 3010310 PMCID： PMC323316 DOI： 10.1073/pnas.83.8.2453

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

33 in total

Review 1. Cellular oncogenes and retroviruses.

Authors: J M Bishop
Journal: Annu Rev Biochem Date: 1983 Impact factor: 23.643

2. Structure and expression of mouse VL30 genes.

Authors: C P Hodgson; P K Elder; T Ono; D N Foster; M J Getz
Journal: Mol Cell Biol Date: 1983-12 Impact factor: 4.272

3. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

Authors: H Land; L F Parada; R A Weinberg
Journal: Nature Date: 1983 Aug 18-24 Impact factor: 49.962

4. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor.

Authors: K Kelly; B H Cochran; C D Stiles; P Leder
Journal: Cell Date: 1983-12 Impact factor: 41.582

5. Molecular cloning of gene sequences regulated by platelet-derived growth factor.

Authors: B H Cochran; A C Reffel; C D Stiles
Journal: Cell Date: 1983-07 Impact factor: 41.582

6. A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.

Authors: R Ross; J Glomset; B Kariya; L Harker
Journal: Proc Natl Acad Sci U S A Date: 1974-04 Impact factor: 11.205

7. Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

Authors: R K Assoian; A Komoriya; C A Meyers; D M Miller; M B Sporn
Journal: J Biol Chem Date: 1983-06-10 Impact factor: 5.157

8. Human-proto-oncogene nucleotide sequences corresponding to the transforming region of simian sarcoma virus.

Authors: S F Josephs; C Guo; L Ratner; F Wong-Staal
Journal: Science Date: 1984-02-03 Impact factor: 47.728

Review 9. A model of cell cycle control: sequential events regulated by growth factors.

Authors: E J O'Keefe; W J Pledger
Journal: Mol Cell Endocrinol Date: 1983-08 Impact factor: 4.102

10. Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.

Authors: M D Waterfield; G T Scrace; N Whittle; P Stroobant; A Johnsson; A Wasteson; B Westermark; C H Heldin; J S Huang; T F Deuel
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Authors: J Tiesman; A Rizzino
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Journal: Pediatr Nephrol Date: 1990-07 Impact factor: 3.714

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Authors: T Etoh; A Igarashi; K Iozumi; Y Ishibashi; K Takehara
Journal: Arch Dermatol Res Date: 1990 Impact factor: 3.017

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Authors: C A Tozzi; G J Poiani; A M Harangozo; C D Boyd; D J Riley
Journal: J Clin Invest Date: 1989-09 Impact factor: 14.808

Review 7. Growth inhibitors: molecular diversity and roles in cell proliferation.

Authors: K Miyazaki; T Horio
Journal: In Vitro Cell Dev Biol Date: 1989-10

8. Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions.

Authors: H Meunier; C Rivier; R M Evans; W Vale
Journal: Proc Natl Acad Sci U S A Date: 1988-01 Impact factor: 11.205

9. Integral role of platelet-derived growth factor in mediating transforming growth factor-β1-dependent mesenchymal stem cell stiffening.

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10. Transforming growth factor beta 1-responsive element: closely associated binding sites for USF and CCAAT-binding transcription factor-nuclear factor I in the type 1 plasminogen activator inhibitor gene.

Authors: A Riccio; P V Pedone; L R Lund; T Olesen; H S Olsen; P A Andreasen
Journal: Mol Cell Biol Date: 1992-04 Impact factor: 4.272