Literature DB >> 3006668

Sequence and interspecies transfer of an aminoglycoside phosphotransferase gene (APH) of Bacillus circulans. Self-defence mechanism in antibiotic-producing organisms.

C J Herbert, M Sarwar, S S Ner, I G Giles, M Akhtar.   

Abstract

The APH gene of a butirosin-producing Bacillus circulans was cloned and shown to be expressed in Escherichia coli and Streptomyces lividans. The gene was sequenced and a possible developmentally regulated promoter identified. When the deduced protein sequence was compared with those from transposon Tn5, transposon Tn903, Streptomyces fradiae, Staphylococcus aureus and Streptococcus faecalis, significant homology was found, indicating that the genes may have a common origin.

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Year:  1986        PMID： 3006668      PMCID： PMC1153039          DOI： 10.1042/bj2330383

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  38 in total

1.  A general method applicable to the search for similarities in the amino acid sequence of two proteins.

Authors:  S B Needleman; C D Wunsch
Journal:  J Mol Biol       Date:  1970-03       Impact factor: 5.469

2.  The sequence of an antibiotic resistance gene from an antibiotic-producing bacterium. Homologies with transposon genes.

Authors:  C J Herbert; I G Giles; M Akhtar
Journal:  FEBS Lett       Date:  1983-08-22       Impact factor: 4.124

3.  Two RNA polymerase sigma factors from Bacillus subtilis discriminate between overlapping promoters for a developmentally regulated gene.

Authors:  W C Johnson; C P Moran; R Losick
Journal:  Nature       Date:  1983-04-28       Impact factor: 49.962

Review 4.  Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria.

Authors:  T J Foster
Journal:  Microbiol Rev       Date:  1983-09

5.  Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5.

Authors:  E Beck; G Ludwig; E A Auerswald; B Reiss; H Schaller
Journal:  Gene       Date:  1982-10       Impact factor: 3.688

6.  Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids.

Authors:  C J Thompson; G S Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

7.  Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3'5"-aminoglycoside phosphotransferase type III.

Authors:  P Trieu-Cuot; P Courvalin
Journal:  Gene       Date:  1983-09       Impact factor: 3.688

8.  Close contacts between sigma 37-RNA polymerase and a Bacillus subtilis chromosomal promoter.

Authors:  C P Moran; W C Johnson; R Losick
Journal:  J Mol Biol       Date:  1982-12-15       Impact factor: 5.469

9.  New effective method for the synthesis of oligonucleotides via phosphotriester intermediates.

Authors:  V A Efimov; S V Reverdatto; O G Chakhmakhcheva
Journal:  Nucleic Acids Res       Date:  1982-11-11       Impact factor: 16.971

10.  Nucleotide sequences that signal the initiation of transcription and translation in Bacillus subtilis.

Authors:  C P Moran; N Lang; S F LeGrice; G Lee; M Stephens; A L Sonenshein; J Pero; R Losick
Journal:  Mol Gen Genet       Date:  1982
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  9 in total

1.  A second streptomycin resistance gene from Streptomyces griseus codes for streptomycin-3"-phosphotransferase. Relationships between antibiotic and protein kinases.

Authors:  P Heinzel; O Werbitzky; J Distler; W Piepersberg
Journal:  Arch Microbiol       Date:  1988       Impact factor: 2.552

2.  Transformation of Arthrobacter and studies on the transcription of the Arthrobacter ermA gene in Streptomyces lividans and Escherichia coli.

Authors:  A N Roberts; L Barnett; S Brenner
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857

3.  Gene cluster for streptomycin biosynthesis in Streptomyces griseus: analysis of a central region including the major resistance gene.

Authors:  J Distler; C Braun; A Ebert; W Piepersberg
Journal:  Mol Gen Genet       Date:  1987-06

4.  A mutant neomycin phosphotransferase II gene reduces the resistance of transformants to antibiotic selection pressure.

Authors:  R L Yenofsky; M Fine; J W Pellow
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

5.  Cloning of aminoglycoside phosphotransferase (APH) gene from antibiotic-producing strain of Bacillus circulans into a high-expression vector, pKK223-3. Purification, properties and location of the enzyme.

Authors:  M Sarwar; M Akhtar
Journal:  Biochem J       Date:  1990-06-15       Impact factor: 3.857

Review 6.  Versatility of aminoglycosides and prospects for their future.

Authors:  Sergei B Vakulenko; Shahriar Mobashery
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

Review 7.  Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

Authors:  K J Shaw; P N Rather; R S Hare; G H Miller
Journal:  Microbiol Rev       Date:  1993-03

8.  Chromosomal aadD2 encodes an aminoglycoside nucleotidyltransferase in Bacillus clausii.

Authors:  Bülent Bozdogan; Sébastien Galopin; Guy Gerbaud; Patrice Courvalin; Roland Leclercq
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191

Review 9.  Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance.

Authors:  Kun Shi; Shane J Caldwell; Desiree H Fong; Albert M Berghuis
Journal:  Front Cell Infect Microbiol       Date:  2013-06-25       Impact factor: 5.293
  9 in total

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