| Literature DB >> 30061735 |
Silong Sun1, Yingsi Zhou1, Jian Chen1, Junpeng Shi1, Haiming Zhao1, Hainan Zhao1, Weibin Song1, Mei Zhang1,2, Yang Cui1, Xiaomei Dong1, Han Liu1, Xuxu Ma1, Yinping Jiao3, Bo Wang3, Xuehong Wei3, Joshua C Stein3, Jeff C Glaubitz4, Fei Lu5,6,7, Guoliang Yu8, Chengzhi Liang9, Kevin Fengler10, Bailin Li11, Antoni Rafalski11, Patrick S Schnable12, Doreen H Ware3,13, Edward S Buckler5,13, Jinsheng Lai14,15.
Abstract
Maize is an important crop with a high level of genome diversity and heterosis. The genome sequence of a typical female line, B73, was previously released. Here, we report a de novo genome assembly of a corresponding male representative line, Mo17. More than 96.4% of the 2,183 Mb assembled genome can be accounted for by 362 scaffolds in ten pseudochromosomes with 38,620 annotated protein-coding genes. Comparative analysis revealed large gene-order and gene structural variations: approximately 10% of the annotated genes were mutually nonsyntenic, and more than 20% of the predicted genes had either large-effect mutations or large structural variations, which might cause considerable protein divergence between the two inbred lines. Our study provides a high-quality reference-genome sequence of an important maize germplasm, and the intraspecific gene order and gene structural variations identified should have implications for heterosis and genome evolution.Entities:
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Year: 2018 PMID： 30061735 DOI： 10.1038/s41588-018-0182-0
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330