Literature DB >> 2991143

A convenient method for the preparation of 99mTc(V)dimercaptosuccinic acid (99mTc(V)-DMSA).

G Westera, A Gadze, W Horst.   

Abstract

Tc(IV)-DMSA for kidney scintigraphy has been prepared in acidic solution. Once the labeling is done in basic solution, upon addition of a small amount of NaHCO3, a mixture of 3-4 other DMSA-complexes is formed, presumably containing Tc(V). Kidney uptake in male adult rats of the 99mTc(V)-DMSA is 1.6% injected dose/g (4.9%/total organ) compared to 16.4% injected dose/g (resp. 50.3%/total organ) for 99mTc(IV)-DMSA.

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Year:  1985        PMID: 2991143     DOI: 10.1016/0020-708x(85)90091-2

Source DB:  PubMed          Journal:  Int J Appl Radiat Isot        ISSN: 0020-708X


  7 in total

1.  Preparation and evaluation of 99mTc(V)-DMSA complex: studies in medullary carcinoma of thyroid.

Authors:  N Ramamoorthy; S V Shetye; P M Pandey; R S Mani; M C Patel; R B Patel; P Ramanathan; B A Krishna; S M Sharma
Journal:  Eur J Nucl Med       Date:  1987

2.  Evidence that 99mTc-(V)-DMSA uptake is mediated by NaPi cotransporter type III in tumour cell lines.

Authors:  Delphine Denoyer; Nathalie Perek; Nathalie Le Jeune; Delphine Frere; Francis Dubois
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-10-14       Impact factor: 9.236

3.  Oxygen bubbling can improve the labelling of pentavalent technetium-99m dimercaptosuccinic acid.

Authors:  H Kobayashi; K H Suzuki; H Sakahara; Z S Yao; A Yokoyama; J Konishi
Journal:  Eur J Nucl Med       Date:  1995-06

4.  Preparation and clinical evaluation of technetium-99m dimercaptosuccinic acid for tumour scintigraphy.

Authors:  T Hirano; K Tomiyoshi; Y J Zhang; T Ishida; T Inoue; K Endo
Journal:  Eur J Nucl Med       Date:  1994-01

5.  Clinical evaluation of 99mTc(V)-dimercapto succinic acid (DMSA) for imaging medullary carcinoma of thyroid and its metastasis.

Authors:  M C Patel; R B Patel; P Ramanathan; N Ramamoorthy; B A Krishna; S M Sharma
Journal:  Eur J Nucl Med       Date:  1988

6.  Relationship of cell proliferation (Ki-67) to 99mTc-(V)DMSA uptake in breast cancer.

Authors:  Vassilios J Papantoniou; Michael A Souvatzoglou; Varvara J Valotassiou; Androniki N Louvrou; Constantina Ambela; John Koutsikos; Dimitrios Lazaris; Julie K Christodoulidou; Maria G Sotiropoulou; Maria J Melissinou; Aris Perperoglou; Spyridon Tsiouris; Cherry J Zerva
Journal:  Breast Cancer Res       Date:  2003-12-11       Impact factor: 6.466

7.  Assessment of tracer 99mTc(V)-DMSA uptake as a measure of tumor cell proliferation in vitro.

Authors:  Fatma J Al-Saeedi; Princy M Mathew; Yunus A Luqmani
Journal:  PLoS One       Date:  2013-01-15       Impact factor: 3.240

  7 in total

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