Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Prediction of similar transforming regions in simian virus 40 large T, adenovirus E1A, and myc oncoproteins.

Literature DB >> 2965766

Prediction of similar transforming regions in simian virus 40 large T, adenovirus E1A, and myc oncoproteins.

J Figge¹, T Webster, T F Smith, E Paucha.

Abstract

Regions containing similar elements of primary and predicted secondary structure were identified in simian virus 40 large T, adenovirus E1A, c-myc and v-myc proteins by a computer program with a set of highly specific, complex pattern descriptors. In all cases these regions were localized in domains of the respective proteins known to be required for transforming activity. We suggest that these apparently structurally similar regions may mediate a common biological function.

Entities: Species

Mesh：

Substances：

Year: 1988 PMID： 2965766 PMCID： PMC253237

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

38 in total

1. Occurrence of phosphorylated residues in predicted beta-turns: implications for beta-turn participation in control mechanisms.

Authors: D Small; P Y Chou; G D Fasman
Journal: Biochem Biophys Res Commun Date: 1977-11-07 Impact factor: 3.575

2. Conservation of chain reversal regions in proteins.

Authors: P Y Chou; G D Fasman
Journal: Biophys J Date: 1979-06 Impact factor: 4.033

3. Prediction of beta-turns.

Authors: P Y Chou; G D Fasman
Journal: Biophys J Date: 1979-06 Impact factor: 4.033

4. A modified Chou and Fasman protein structure algorithm.

Authors: W W Ralph; T Webster; T F Smith
Journal: Comput Appl Biosci Date: 1987-09

Review 5. Prediction of the secondary structure of proteins from their amino acid sequence.

Authors: P Y Chou; G D Fasman
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1978

6. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

Authors: H Land; L F Parada; R A Weinberg
Journal: Nature Date: 1983 Aug 18-24 Impact factor: 49.962

7. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture.

Authors: H E Ruley
Journal: Nature Date: 1983 Aug 18-24 Impact factor: 49.962

Review 8. Casein kinases--multipotential protein kinases.

Authors: G M Hathaway; J A Traugh
Journal: Curr Top Cell Regul Date: 1982

9. Substrate specificity of the nuclear protein kinase NII from porcine liver. Studies with casein variants.

Authors: J Hoppe; H Baydoun
Journal: Eur J Biochem Date: 1981-07

10. Simian virus 40 large T antigen is phosphorylated at multiple sites clustered in two separate regions.

Authors: K H Scheidtmann; B Echle; G Walter
Journal: J Virol Date: 1982-10 Impact factor: 5.103

38 in total

1. Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins.

Authors: F A Dick; E Sailhamer; N J Dyson
Journal: Mol Cell Biol Date: 2000-05 Impact factor: 4.272

2. RRB1 and RRB2 encode maize retinoblastoma-related proteins that interact with a plant D-type cyclin and geminivirus replication protein.

Authors: R A Ach; T Durfee; A B Miller; P Taranto; L Hanley-Bowdoin; P C Zambryski; W Gruissem
Journal: Mol Cell Biol Date: 1997-09 Impact factor: 4.272

3. An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

Authors: G J Kato; J Barrett; M Villa-Garcia; C V Dang
Journal: Mol Cell Biol Date: 1990-11 Impact factor: 4.272

4. The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens.

Authors: D C Pallas; W Weller; S Jaspers; T B Miller; W S Lane; T M Roberts
Journal: J Virol Date: 1992-02 Impact factor: 5.103

5. Adenovirus E1A makes two distinct contacts with the retinoblastoma protein.

Authors: N Dyson; P Guida; C McCall; E Harlow
Journal: J Virol Date: 1992-07 Impact factor: 5.103

6. Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization.

Authors: A Larose; N Dyson; M Sullivan; E Harlow; M Bastin
Journal: J Virol Date: 1991-05 Impact factor: 5.103

7. Image analysis quantitation of immunoreactive retinoblastoma protein in human thyroid neoplasms with a streptavidin-biotin-peroxidase staining technique.

Authors: J Figge; G Bakst; D Weisheit; O Solis; J S Ross
Journal: Am J Pathol Date: 1991-12 Impact factor: 4.307

8. pRB-E2F1 complexes are resistant to adenovirus E1A-mediated disruption.

Authors: L A Seifried; S Talluri; M Cecchini; L M Julian; J S Mymryk; F A Dick
Journal: J Virol Date: 2008-02-27 Impact factor: 5.103

Review 9. Expression and interactions of human adenovirus oncoproteins.

Authors: P A Boulanger; G E Blair
Journal: Biochem J Date: 1991-04-15 Impact factor: 3.857

10. Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products.

Authors: P Yaciuk; M C Carter; J M Pipas; E Moran
Journal: Mol Cell Biol Date: 1991-04 Impact factor: 4.272