| Literature DB >> 29629441 |
X Shang1, Y Chen, N Wang, W Niu, J Guo.
Abstract
We report a strategy to introduce a reactive electrophile into proteins through the conversion of a chemically inert group into a bioreactive group in response to an inducer molecule. This strategy was demonstrated by oxidation-induced and proximity-enhanced protein-protein crosslinking in the presence of a large excess of free nucleophile.Entities:
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Year: 2018 PMID: 29629441 PMCID: PMC5908726 DOI: 10.1039/c8cc01639a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222