| Literature DB >> 12148987 |
Jason W Chin1, Stephen W Santoro, Andrew B Martin, David S King, Lei Wang, Peter G Schultz.
Abstract
We report the selection of a new orthogonal aminoacyl tRNA synthetase/tRNA pair for the in vivo incorporation of a photocrosslinker, p-azido-l-phenylalanine, into proteins in response to the amber codon, TAG. The amino acid is incorporated in good yield with high fidelity and can be used to crosslink interacting proteins.Entities:
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Year: 2002 PMID: 12148987 DOI: 10.1021/ja027007w
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419