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Literature DB >> 29547714

Advancing the Frontiers of Chemical Protein Synthesis-The 7^th CPS Meeting, Haifa, Israel.

Abstract

The 7th Chemical Protein Synthesis Meeting took place in September 2017 in Haifa, Israel, bringing together 100 scientists from 11 countries. The cutting-edge scientific program included new synthetic strategies and ligation auxiliaries, novel insights into protein signaling and post-translational modifications, and a range of promising therapeutic applications.

Entities: Chemical

Mesh：

Substances：
Proteins

Year: 2018 PMID： 29547714 PMCID： PMC5892704 DOI： 10.1016/j.chembiol.2018.03.001

Source DB: PubMed Journal: Cell Chem Biol ISSN： 2451-9448 Impact factor: 8.116

91 in total

1. A fully automated flow-based approach for accelerated peptide synthesis.

Authors: Alexander J Mijalis; Dale A Thomas; Mark D Simon; Andrea Adamo; Ryan Beaumont; Klavs F Jensen; Bradley L Pentelute
Journal: Nat Chem Biol Date: 2017-02-28 Impact factor: 15.040

2. Cross-linking reveals laminin coiled-coil architecture.

Authors: Gad Armony; Etai Jacob; Toot Moran; Yishai Levin; Tevie Mehlman; Yaakov Levy; Deborah Fass
Journal: Proc Natl Acad Sci U S A Date: 2016-11-04 Impact factor: 11.205

3. Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure.

Authors: Kelly L George; W Seth Horne
Journal: J Am Chem Soc Date: 2017-06-05 Impact factor: 15.419

4. Semisynthesis of autophagy protein LC3 conjugates.

Authors: Aimin Yang; Inken Hacheney; Yao-Wen Wu
Journal: Bioorg Med Chem Date: 2017-05-24 Impact factor: 3.641

5. Substrate Recognition of Glycoprotein Folding Sensor UGGT Analyzed by Site-Specifically ¹⁵N-Labeled Glycopeptide and Small Glycopeptide Library Prepared by Parallel Native Chemical Ligation.

Authors: Masayuki Izumi; Rie Kuruma; Ryo Okamoto; Akira Seko; Yukishige Ito; Yasuhiro Kajihara
Journal: J Am Chem Soc Date: 2017-08-10 Impact factor: 15.419

10. A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins.

Authors: N Ollivier; R Desmet; H Drobecq; A Blanpain; E Boll; B Leclercq; A Mougel; J Vicogne; O Melnyk
Journal: Chem Sci Date: 2017-05-30 Impact factor: 9.825

1 in total

Review 1. Novel protein science enabled by total chemical synthesis.

Authors: Stephen B H Kent
Journal: Protein Sci Date: 2018-12-18 Impact factor: 6.725

1 in total

Advancing the Frontiers of Chemical Protein Synthesis-The 7^th CPS Meeting, Haifa, Israel.

1. A fully automated flow-based approach for accelerated peptide synthesis.

2. Cross-linking reveals laminin coiled-coil architecture.

3. Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure.

4. Semisynthesis of autophagy protein LC3 conjugates.

5. Substrate Recognition of Glycoprotein Folding Sensor UGGT Analyzed by Site-Specifically ¹⁵N-Labeled Glycopeptide and Small Glycopeptide Library Prepared by Parallel Native Chemical Ligation.

Review 6. Serotonylation and Transamidation of Other Monoamines.

7. Protein chemical synthesis by α-ketoacid-hydroxylamine ligation.

8. Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation.

Review 9. Nanobodies: Chemical Functionalization Strategies and Intracellular Applications.

10. A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins.

Review 1. Novel protein science enabled by total chemical synthesis.