Literature DB >> 29536995

Melting proteins confined in nanodroplets with 10.6 μm light provides clues about early steps of denaturation.

Tarick J El-Baba1, Daniel R Fuller, Daniel W Woodall, Shannon A Raab, Christopher R Conant, Jonathan M Dilger, Yoni Toker, Evan R Williams, David H Russell, David E Clemmer.   

Abstract

Ubiquitin confined within nanodroplets was irradiated with a variable-power CO2 laser. Mass spectrometry analysis shows evidence for a protein "melting"-like transition within droplets prior to solvent evaporation and ion formation. Ion mobility spectrometry reveals that structures associated with early steps of denaturation are trapped because of short droplet lifetimes.

Entities:  

Year:  2018        PMID： 29536995      PMCID： PMC5871606          DOI： 10.1039/c7cc09829d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  37 in total

1.  Thermal dissociation of multimeric protein complexes by using nanoelectrospray mass spectrometry.

Authors:  Justin L P Benesch; Frank Sobott; Carol V Robinson
Journal:  Anal Chem       Date:  2003-05-15       Impact factor: 6.986

2.  An IMS-IMS analogue of MS-MS.

Authors:  Stormy L Koeniger; Samuel I Merenbloom; Stephen J Valentine; Martin F Jarrold; Harold R Udseth; Richard D Smith; David E Clemmer
Journal:  Anal Chem       Date:  2006-06-15       Impact factor: 6.986

3.  Denaturation of alpha-lactalbumin and ubiquitin studied by electrospray and laser spray.

Authors:  Masana Nakamura; Atsushi Takamizawa; Hideki Yamada; Kenzo Hiraoka; Satoko Akashi
Journal:  Rapid Commun Mass Spectrom       Date:  2007       Impact factor: 2.419

4.  Characterization of a partially denatured state of a protein by two-dimensional NMR: reduction of the hydrophobic interactions in ubiquitin.

Authors:  M M Harding; D H Williams; D N Woolfson
Journal:  Biochemistry       Date:  1991-03-26       Impact factor: 3.162

5.  Melting Proteins: Evidence for Multiple Stable Structures upon Thermal Denaturation of Native Ubiquitin from Ion Mobility Spectrometry-Mass Spectrometry Measurements.

Authors:  Tarick J El-Baba; Daniel W Woodall; Shannon A Raab; Daniel R Fuller; Arthur Laganowsky; David H Russell; David E Clemmer
Journal:  J Am Chem Soc       Date:  2017-04-26       Impact factor: 15.419

6.  Photodissociation of conformer-selected ubiquitin ions reveals site-specific cis/trans isomerization of proline peptide bonds.

Authors:  Stephan Warnke; Carsten Baldauf; Michael T Bowers; Kevin Pagel; Gert von Helden
Journal:  J Am Chem Soc       Date:  2014-07-09       Impact factor: 15.419

7.  Thermodynamics of ubiquitin unfolding.

Authors:  P L Wintrode; G I Makhatadze; P L Privalov
Journal:  Proteins       Date:  1994-03

8.  Dissecting the structure of a partially folded protein. Circular dichroism and nuclear magnetic resonance studies of peptides from ubiquitin.

Authors:  J P Cox; P A Evans; L C Packman; D H Williams; D N Woolfson
Journal:  J Mol Biol       Date:  1993-11-20       Impact factor: 5.469

9.  Effects of charge state on fragmentation pathways, dynamics, and activation energies of ubiquitin ions measured by blackbody infrared radiative dissociation.

Authors:  R A Jockusch; P D Schnier; W D Price; E F Strittmatter; P A Demirev; E R Williams
Journal:  Anal Chem       Date:  1997-03-15       Impact factor: 6.986

10.  Hydrogen exchange in native and alcohol forms of ubiquitin.

Authors:  Y Pan; M S Briggs
Journal:  Biochemistry       Date:  1992-11-24       Impact factor: 3.162
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  10 in total

1.  Characterizing Thermal Transitions of IgG with Mass Spectrometry.

Authors:  Christopher J Brown; Daniel W Woodall; Tarick J El-Baba; David E Clemmer
Journal:  J Am Soc Mass Spectrom       Date:  2019-07-30       Impact factor: 3.109

2.  Structural Analysis of the Effect of a Dual-FLAG Tag on Transthyretin.

Authors:  Mehdi Shirzadeh; Michael L Poltash; Arthur Laganowsky; David H Russell
Journal:  Biochemistry       Date:  2020-03-02       Impact factor: 3.162

3.  Substance P in the Gas Phase: Conformational Changes and Dissociations Induced by Collisional Activation in a Drift Tube.

Authors:  Christopher R Conant; Daniel R Fuller; Zhichao Zhang; Daniel W Woodall; David H Russell; David E Clemmer
Journal:  J Am Soc Mass Spectrom       Date:  2019-04-12       Impact factor: 3.109

Review 4.  Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions.

Authors:  Arthur Laganowsky; David E Clemmer; David H Russell
Journal:  Annu Rev Biophys       Date:  2021-12-21       Impact factor: 19.763

Review 5.  THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY-MASS SPECTROMETRY.

Authors:  Jacob W McCabe; Michael J Hebert; Mehdi Shirzadeh; Christopher S Mallis; Joanna K Denton; Thomas E Walker; David H Russell
Journal:  Mass Spectrom Rev       Date:  2020-07-01       Impact factor: 10.946

6.  Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding.

Authors:  Jacob W McCabe; Mehdi Shirzadeh; Thomas E Walker; Cheng-Wei Lin; Benjamin J Jones; Vicki H Wysocki; David P Barondeau; David E Clemmer; Arthur Laganowsky; David H Russell
Journal:  Anal Chem       Date:  2021-04-27       Impact factor: 6.986

7.  Thermal Analysis of a Mixture of Ribosomal Proteins by vT-ESI-MS: Toward a Parallel Approach for Characterizing the Stabilitome.

Authors:  Tarick J El-Baba; Shannon A Raab; Rachel P Buckley; Christopher J Brown; Corinne A Lutomski; Lucas W Henderson; Daniel W Woodall; Jiangchuan Shen; Jonathan C Trinidad; Hengyao Niu; Martin F Jarrold; David H Russell; Arthur Laganowsky; David E Clemmer
Journal:  Anal Chem       Date:  2021-06-08       Impact factor: 8.008

Review 8.  Temperature-Controlled Electrospray Ionization: Recent Progress and Applications.

Authors:  Julian Alexander Harrison; Adam Pruška; Irina Oganesyan; Philipp Bittner; Renato Zenobi
Journal:  Chemistry       Date:  2021-11-05       Impact factor: 5.020

9.  Time-resolved universal temperature measurements using NaYF4:Er3+,Yb3+ upconverting nanoparticles in an electrospray jet.

Authors:  Kristina Shrestha; Arwa A Alaulamie; Ali Rafiei Miandashti; Hugh H Richardson
Journal:  Beilstein J Nanotechnol       Date:  2018-11-21       Impact factor: 3.649

10.  Understanding the Thermal Denaturation of Myoglobin with IMS-MS: Evidence for Multiple Stable Structures and Trapped Pre-equilibrium States.

Authors:  Daniel W Woodall; Lucas W Henderson; Shannon A Raab; Kenji Honma; David E Clemmer
Journal:  J Am Soc Mass Spectrom       Date:  2020-07-07       Impact factor: 3.109
  10 in total

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