| Literature DB >> 29528199 |
Ewa Juresic1, Gary P Liney1,2,3,4, Robba Rai1,2,3, Joseph Descalar3, Mark Lee1,2, Karen Wong1,2,3, Daniel Moses5,6,7, Jacqueline Veera8, Lois Holloway1,2,3,4,9,10.
Abstract
INTRODUCTION: A magnetic resonance (MR) scanner for radiotherapy treatment simulation was commissioned in our department in June 2013. Practical set up and MR image quality trade-offs using a variety of patient positions and immobilisation devices routinely used in the treatment planning of rectal cancer patients were considered. The study also aimed to investigate the MR compatibility of the device materials with a focus on temperature changes during routine clinical examinations.Entities:
Keywords: Advanced practice; cancer; clinical site; gastro intestinal; general; magnetic resonance imaging
Mesh:
Year: 2018 PMID: 29528199 PMCID: PMC5846022 DOI: 10.1002/jmrs.266
Source DB: PubMed Journal: J Med Radiat Sci ISSN: 2051-3895
Figure 1(a) MRI scans from Volunteer 1, images are in the prone, supine, prone with the MR compatible bellyboard (WBB) and the Contoura bellyboard (BBB) setup positions. (b) MRI scans from Volunteer 8 images are in the prone, supine, prone with the MR compatible bellyboard (WBB) and the Contoura bellyboard (BBB) set up positions.
Position of the temperature strip placement as used for assessment of potential temperature changes during MRI scans
| Volunteer positioning | Temperature strip location |
|---|---|
| Supine |
Inferior part of the volunteer bellybutton The small of the volunteers back |
| Prone (No Bellyboard) |
Inferior part of the volunteer bellybutton The small of the volunteers back |
| Prone (On Bellyboard) |
Pubic symphysis Inferior part of the volunteer bellybutton The small of the volunteers back On the curved ridge of each bellyboard, on a foam blue sponge. |
Image scoring system used for semi‐quantitative analysis. A score of 1 demonstrating a highly useful image for radiotherapy contouring purposes and a score of 4 demonstrating an image of limited usefulness for radiotherapy contouring purposes
| Score | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
| Rectal wall definition | Rectal wall clearly defined | Rectal wall edge slightly blurred, not impairing definition of Rectal Wall boundary. | Considerable blurring of rectal wall edge impacting on accurate definition of Rectal Wall boundary. | Significant blurring of rectal wall, definition of rectal wall boundary not achievable |
| Mesorectum definition | Mesorectum clearly defined | Mesorectum slightly blurred, not impairing definition of mesorectum boundary. | Considerable blurring of mesorectum impacting on accurate definition of rectal wall boundary. | Significant blurring of mesorectum, definition of mesorectum boundary not achievable |
| Bladder definition | Bladder wall clearly defined | Bladder wall slightly blurred, not impairing definition of bladder boundary. | Considerable blurring of bladder wall impacting on accurate definition of bladder boundary. | Significant blurring of bladder wall, definition of bladder boundary not achievable |
| Prostate/uterus definition | Prostate/uterus edge clearly defined | Prostate/uterus edge slightly blurred, not impairing definition of prostate/uterus boundary. | Considerable blurring of prostate/uterus edge impacting on accurate definition of prostate/uterus boundary | Significant blurring of prostate/uterus edge, definition of prostate/uterus boundary not achievable |
| Small bowel definition | Small bowel edge clearly defined | Small bowel edge slightly blurred, not impairing definition of small bowel boundary. | Considerable blurring of small bowel edge impacting on accurate definition of Small Bowel boundary | Significant blurring of small bowel edge, small bowel boundary not achievable |
| Artefacts | No artefacts | Little artefact not impairing image quality | Considerable artefact impacting evaluation of anatomical structures | Extreme artefacts obscuring delineation of anatomical structures |
| Image noise | Minimal noise | Little noise not impairing diagnostic image quality | Considerable noise impacts the evaluation of anatomical structures. | Extreme noise obscuring delineation of anatomical structures. |
| Overall image quality | Very good image quality | Fair image quality not impairing the delineation of structures | Impaired image quality that may lead to incorrect delineation | Structures not definable |
Figure 2Average maximum recorded temperature at each of the measurement positions for the different set up positions.
Comparison of image signal to noise ratio (SNR) between positions by section
| Comparison | Difference | 95% confidence interval |
|
|---|---|---|---|
| Fatty anterior | |||
| BBB versus Prone | −120.7 | (−211.0, −30.5) | 0.009 |
| BBB versus WBB | −62.8 | (−153.0, 27.5) | 0.170 |
| BBB versus Supine | −339.2 | (−429.5, −249.0) | <0.001 |
| Prone versus WBB | 58.0 | (−32.3, 148.2) | 0.210 |
| Prone versus Supine | −218.5 | (−308.8, −128.2) | <0.001 |
| WBB versus Supine | −276.5 | (−366.7, −186.2) | <0.001 |
| Fatty posterior | |||
| BBB versus Prone | 90.2 | (−0.1, 180.5) | 0.050 |
| BBB versus WBB | −146.9 | (−237.2, −56.6) | 0.002 |
| BBB versus Supine | 57.1 | (−33.2, 147.4) | 0.210 |
| Prone versus WBB | −237.1 | (−327.4, −146.9) | <0.001 |
| Prone versus Supine | −33.1 | (−123.4, 57.1) | 0.470 |
| WBB versus Supine | 204.0 | (113.7, 294.3) | <0.001 |
| Muscle anterior | |||
| BBB versus Prone | −15.9 | (−106.2, 74.4) | 0.728 |
| BBB versus WBB | −4.0 | (−94.2, 86.3) | 0.931 |
| BBB versus Supine | −19.9 | (−110.1, 70.4) | 0.665 |
| Prone versus WBB | 12.0 | (−78.3, 102.2) | 0.794 |
| Prone versus Supine | −4.0 | (−94.2, 86.3) | 0.931 |
| WBB versus Supine | −15.9 | (−106.2, 74.4) | 0.728 |
| Muscle posterior | |||
| BBB versus Prone | 4.9 | (−85.4, 95.2) | 0.915 |
| BBB versus WBB | −18.4 | (−108.7, 71.8) | 0.687 |
| BBB versus Supine | 2.7 | (−87.6, 92.9) | 0.954 |
| Prone versus WBB | −23.3 | (−113.6, 66.9) | 0.611 |
| Prone versus Supine | −2.3 | (−92.5, 88.0) | 0.961 |
| WBB versus Supine | 21.1 | (−69.2, 111.4) | 0.645 |
| Organ mid | |||
| BBB versus Prone | −11.0 | (−101.2, 79.3) | 0.810 |
| BBB versus WBB | −24.1 | (−114.4, 66.2) | 0.599 |
| BBB versus Supine | −41.2 | (−131.5, 49.0) | 0.369 |
| Prone versus WBB | −13.1 | (−103.4, 77.2) | 0.775 |
| Prone versus Supine | −30.2 | (−120.5, 60.0) | 0.509 |
| WBB versus Supine | −17.1 | (−107.4, 73.2) | 0.709 |
Results are based on a random coefficient linear mixed model using volunteers as the random effect, with variables position, section and an interaction between position and section (Interaction P < 0.0001). BBB, Civco Contoura Bellyboard; WBB, MR Series Bellyboard.
Figure 3Mean overall observer scores for each organ considered and each imaging set up position, the error bars represent a single standard deviation.
Comparison of image scores between positions by organ
| Comparison | Difference | 95% confidence interval |
|
|---|---|---|---|
| Bladder | |||
| BBB versus Prone | 0.10 | (−0.21, 0.41) | 0.524 |
| BBB versus WBB | 0.08 | (−0.23, 0.38) | 0.633 |
| BBB versus Supine | 0.15 | (−0.16, 0.46) | 0.339 |
| Prone versus WBB | −0.03 | (−0.33, 0.28) | 0.873 |
| Prone versus Supine | 0.05 | (−0.26, 0.36) | 0.750 |
| WBB versus Supine | 0.08 | (−0.23, 0.38) | 0.633 |
| Mesorectum | |||
| BBB versus Prone | 0.10 | (−0.21, 0.41) | 0.524 |
| BBB versus WBB | 0.13 | (−0.18, 0.43) | 0.426 |
| BBB versus Supine | 0.58 | (0.27, 0.88) | <0.001 |
| Prone versus WBB | 0.03 | (−0.28, 0.33) | 0.873 |
| Prone versus Supine | 0.48 | (0.17, 0.78) | 0.003 |
| WBB versus Supine | 0.45 | (0.14, 0.76) | 0.004 |
| Prostate/uterus | |||
| BBB versus Prone | 0.35 | (0.04, 0.66) | 0.026 |
| BBB versus WBB | 0.35 | (0.04, 0.66) | 0.026 |
| BBB versus Supine | 0.58 | (0.27, 0.88) | <0.001 |
| Prone versus WBB | 0.00 | (−0.31, 0.31) | 1.000 |
| Prone versus Supine | 0.23 | (−0.09, 0.53) | 0.152 |
| WBB versus Supine | 0.23 | (−0.09, 0.53) | 0.152 |
| Rectal wall | |||
| BBB versus Prone | 0.20 | (−0.11, 0.51) | 0.203 |
| BBB versus WBB | 0.23 | (−0.09, 0.53) | 0.152 |
| BBB versus Supine | 0.50 | (0.19, 0.81) | 0.002 |
| Prone versus WBB | 0.03 | (−0.28, 0.33) | 0.873 |
| Prone versus Supine | 0.30 | (−0.01, 0.61) | 0.056 |
| WBB versus Supine | 0.28 | (−0.03, 0.58) | 0.080 |
| Small bowel | |||
| BBB versus Prone | 0.25 | (−0.06, 0.56) | 0.111 |
| BBB versus WBB | 0.25 | (−0.06, 0.56) | 0.111 |
| BBB versus Supine | 0.38 | (0.07, 0.68) | 0.017 |
| Prone versus WBB | 0.00 | (−0.31, 0.31) | 1.000 |
| Prone versus Supine | 0.13 | (−0.18, 0.43) | 0.426 |
| WBB versus Supine | 0.13 | (−0.18, 0.43) | 0.426 |
Results are based on a random coefficient linear mixed model using crossed random effects for volunteers and assessors, with variables position, organ and an interaction between position and organ (Organ by position P = 0.7491). BBB, Civco Contoura Bellyboard; WBB, MR Series Bellyboard.
Comparison of image scores between positions by measurement type
| Comparison | Difference | 95% confidence interval |
|
|---|---|---|---|
| Artefact | |||
| BBB versus Prone | 0.03 | (−0.27, 0.32) | 0.866 |
| BBB versus WBB | 0.10 | (−0.19, 0.39) | 0.498 |
| BBB versus Supine | 0.40 | (0.11, 0.69) | 0.007 |
| Prone versus WBB | 0.08 | (−0.22, 0.37) | 0.612 |
| Prone versus Supine | 0.38 | (0.08, 0.67) | 0.011 |
| WBB versus Supine | 0.30 | (0.01, 0.59) | 0.043 |
| Image noise | |||
| BBB versus Prone | 0.10 | (−0.19, 0.39) | 0.498 |
| BBB versus WBB | 0.20 | (−0.09, 0.49) | 0.176 |
| BBB versus Supine | 0.68 | (0.39, 0.97) | <0.001 |
| Prone versus WBB | 0.10 | (−0.19, 0.39) | 0.498 |
| Prone versus Supine | 0.58 | (0.29, 0.87) | <0.001 |
| WBB versus Supine | 0.48 | (0.19, 0.77) | 0.001 |
| Overall image quality | |||
| BBB versus Prone | 0.08 | (−0.22, 0.37) | 0.612 |
| BBB versus WBB | 0.05 | (−0.24, 0.34) | 0.735 |
| BBB versus Supine | 0.38 | (0.09, 0.67) | 0.011 |
| Prone versus WBB | −0.03 | (−0.32, 0.27) | 0.866 |
| Prone versus supine | 0.30 | (0.01, 0.59) | 0.043 |
| WBB versus supine | 0.33 | (0.04, 0.62) | 0.028 |
Results are based on a random coefficient linear mixed model using crossed random effects for volunteers and assessors, with variables position, measurement type and an interaction between position and measurement (Interaction P = 0.7898). BBB, Civco Contoura Bellyboard; WBB, MR Series Bellyboard.