Literature DB >> 2952212

Vasocortin: a novel glucocorticoid-induced anti-inflammatory protein.

R Carnuccio, M Di Rosa, B Guerrasio, T Iuvone, L Sautebin.   

Abstract

The preliminary characterization of ;vasocortin' a novel glucocorticoid-induced anti-inflammatory protein, is described. Vasocortin is released into the rat peritoneal cavity following systemic dexamethasone administration, has an apparent mol. wt. of 100 kD and inhibits rat dextran oedema. Vasocortin is distinct from lipocortin and is likely to be associated with the anti-inflammatory effect of glucocorticoids.

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Year:  1987        PMID: 2952212      PMCID: PMC1917188          DOI: 10.1111/j.1476-5381.1987.tb11193.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  11 in total

1.  Multiple control of inflammation by glucocorticoids.

Authors:  M Di Rosa; A Calignano; R Carnuccio; A Ialenti; L Sautebin
Journal:  Agents Actions       Date:  1986-01

2.  Screens for anti-inflammatory drugs.

Authors:  M Di Rosa; D A Willoughby
Journal:  J Pharm Pharmacol       Date:  1971-04       Impact factor: 3.765

3.  Anti-phospholipase proteins.

Authors:  M Di Rosa; R J Flower; F Hirata; L Parente; F Russo-Marie
Journal:  Prostaglandins       Date:  1984-10

4.  Vasoregulin, a glucocorticoid-inducible vascular permeability inhibitory protein.

Authors:  Y Oyanagui; S Suzuki
Journal:  Agents Actions       Date:  1986-01

5.  Characterization and partial purification of 'renocortins': two polypeptides formed in renal cells causing the anti-phospholipase-like action of glucocorticoids.

Authors:  J F Cloix; O Colard; B Rothhut; F Russo-Marie
Journal:  Br J Pharmacol       Date:  1983-05       Impact factor: 8.739

6.  Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat.

Authors:  G J Blackwell; R Carnuccio; M Di Rosa; R J Flower; C S Langham; L Parente; P Persico; N C Russel-Smith; D Stone
Journal:  Br J Pharmacol       Date:  1982-05       Impact factor: 8.739

7.  The anti-inflammatory effect of glucocorticoid-induced phospholipase inhibitory proteins.

Authors:  A Calignano; R Carnuccio; M Di Rosa; A Ialenti; S Moncada
Journal:  Agents Actions       Date:  1985-03

8.  Hydrocortisone-induced inhibitor of prostaglandin biosynthesis in rat leucocytes.

Authors:  R Carnuccio; M Di Rosa; P Persico
Journal:  Br J Pharmacol       Date:  1980-01       Impact factor: 8.739

9.  A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids.

Authors:  F Hirata; E Schiffmann; K Venkatasubramanian; D Salomon; J Axelrod
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

10.  Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids.

Authors:  G J Blackwell; R Carnuccio; M Di Rosa; R J Flower; L Parente; P Persico
Journal:  Nature       Date:  1980-09-11       Impact factor: 49.962

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  8 in total

1.  Trans-Tenon's retrobulbar triamcinolone infusion for small choroidal neovascularisation.

Authors:  A A Okada; T Wakabayashi; E Kojima; Y Asano; T Hida
Journal:  Br J Ophthalmol       Date:  2004-08       Impact factor: 4.638

2.  Anti-inflammatory effects of vasocortin and nonapeptide fragments of uteroglobin and lipocortin I (antiflammins).

Authors:  A Ialenti; P M Doyle; G N Hardy; D S Simpkin; M Di Rosa
Journal:  Agents Actions       Date:  1990-01

3.  Characterization of a novel anti-inflammatory factor produced by RM3/1 macrophages derived from glucocorticoid treated human monocytes.

Authors:  W Hamann; A Flöter; W Schmutzler; G Zwadlo-Klarwasser
Journal:  Inflamm Res       Date:  1995-12       Impact factor: 4.575

4.  Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

Authors:  G Cirino; S H Peers; R J Flower; J L Browning; R B Pepinsky
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

5.  Selective inhibition by vasocortin of histamine release induced by dextran and concanavalin-A from rat peritoneal cells.

Authors:  R Carnuccio; M Di Rosa; A Ialenti; T Iuvone; L Sautebin
Journal:  Br J Pharmacol       Date:  1989-09       Impact factor: 8.739

6.  Neutral endopeptidase and kininase II mediate glucocorticoid inhibition of neurogenic inflammation in the rat trachea.

Authors:  G Piedimonte; D M McDonald; J A Nadel
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

Review 7.  Physiological perspectives of therapy in bronchial hyperreactivity.

Authors:  L M Pinto Pereira; F A Orrett; M Balbirsingh
Journal:  Can J Anaesth       Date:  1996-07       Impact factor: 5.063

8.  Effect of dexamethasone on neutrophil accumulation and oedema formation in rabbit skin: an investigation of site of action.

Authors:  H Yarwood; S Nourshargh; S Brain; T J Williams
Journal:  Br J Pharmacol       Date:  1993-04       Impact factor: 8.739

  8 in total

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