| Literature DB >> 2478246 |
R Carnuccio1, M Di Rosa, A Ialenti, T Iuvone, L Sautebin.
Abstract
Vasocortin, a glucocorticoid-induced anti-inflammatory protein, has been purified from the peritoneal lavage fluid of dexamethasone-treated rats. Vasocortin inhibited the release of histamine from rat peritoneal cells stimulated by dextran or concanavalin A but did not alter the release induced by calcium ionophore A23187 or compound 48/80. This selective effect exhibited by vasocortin mimics the glucocorticoid inhibition of histamine release from rat mast cells.Entities:
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Year: 1989 PMID: 2478246 PMCID: PMC1854690 DOI: 10.1111/j.1476-5381.1989.tb16857.x
Source DB: PubMed Journal: Br J Pharmacol ISSN: 0007-1188 Impact factor: 8.739