Literature DB >> 7357155

Hydrocortisone-induced inhibitor of prostaglandin biosynthesis in rat leucocytes.

R Carnuccio, M Di Rosa, P Persico.   

Abstract

Rat peritoneal luecocytes incubated with hydrocortisone (10 micrograms/ml) release a factor which inhibits prostaglandin generation. The steroid-induced inhibitor, which mediates the anti-phospholipase effect of antiinflammatory steroids, may be a protein or a polypeptide since its formation is blocked by cycloheximide, a known inhibitor of protein synthesis.

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Year:  1980        PMID： 7357155      PMCID： PMC2044121          DOI： 10.1111/j.1476-5381.1980.tb10691.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  6 in total

1.  A chemotactic role for prostaglandins released from polymorphonuclear leucocytes during phagocytosis.

Authors:  G A Higgs; E McCall; L J Youlten
Journal:  Br J Pharmacol       Date:  1975-04       Impact factor: 8.739

2.  Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation.

Authors:  R J Flower; G J Blackwell
Journal:  Nature       Date:  1979-03-29       Impact factor: 49.962

Review 3.  Mechanism of action of glucocorticoids.

Authors:  E B Thompson; M E Lippman
Journal:  Metabolism       Date:  1974-02       Impact factor: 8.694

4.  The importance of phospholipase-A2 in prostaglandin biosynthesis.

Authors:  R J Flower; G J Blackwell
Journal:  Biochem Pharmacol       Date:  1976-02-01       Impact factor: 5.858

5.  Inhibition of prostaglandin biosynthesis by corticosteroids requires RNA and protein synthesis.

Authors:  A Danon; G Assouline
Journal:  Nature       Date:  1978-06-15       Impact factor: 49.962

6.  Mechanism of inhibition of prostaglandin biosynthesis by hydrocortisone in rat leucocytes.

Authors:  M Di Rosa; P Persico
Journal:  Br J Pharmacol       Date:  1979-06       Impact factor: 8.739
  6 in total
  20 in total

1.  Inhibition of the release of a neutrophil chemotactic factor from macrophages partially explains the anti-inflammatory action of glucocorticoids.

Authors:  F Q Cunha; A T Cacini; S H Ferreira
Journal:  Agents Actions       Date:  1986-01

2.  Multiple control of inflammation by glucocorticoids.

Authors:  M Di Rosa; A Calignano; R Carnuccio; A Ialenti; L Sautebin
Journal:  Agents Actions       Date:  1986-01

3.  Background and discovery of lipocortins.

Authors:  R J Flower
Journal:  Agents Actions       Date:  1986-01

4.  Vasocortin: a novel glucocorticoid-induced anti-inflammatory protein.

Authors:  R Carnuccio; M Di Rosa; B Guerrasio; T Iuvone; L Sautebin
Journal:  Br J Pharmacol       Date:  1987-03       Impact factor: 8.739

Review 5.  Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids.

Authors:  R J Flower
Journal:  Br J Pharmacol       Date:  1988-08       Impact factor: 8.739

6.  Effect of dexamethasone on cyclo-oxygenase activity in reno-medullary cells in culture.

Authors:  F Russo-Marie; C Seillan; D Duval
Journal:  Agents Actions       Date:  1980-12

7.  Characterization and partial purification of 'renocortins': two polypeptides formed in renal cells causing the anti-phospholipase-like action of glucocorticoids.

Authors:  J F Cloix; O Colard; B Rothhut; F Russo-Marie
Journal:  Br J Pharmacol       Date:  1983-05       Impact factor: 8.739

8.  H-2 influences phenytoin binding and inhibition of prostaglandin synthesis.

Authors:  C Gupta; M Katsumata; A S Goldman
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

9.  Studies of glycogen-induced inflammation of mice. Dynamics of inflammatory responses and influence of antiinflammatory drugs and protease inhibitors.

Authors:  T Yamashita; Y Ishibashi; I Nagaoka; K Kasuya; K Masuda; H Warabi; Y Shiokawa
Journal:  Inflammation       Date:  1982-03       Impact factor: 4.092

10.  Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat.

Authors:  G J Blackwell; R Carnuccio; M Di Rosa; R J Flower; C S Langham; L Parente; P Persico; N C Russel-Smith; D Stone
Journal:  Br J Pharmacol       Date:  1982-05       Impact factor: 8.739
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