Literature DB >> 29463958

Interfractional diaphragm changes during breath-holding in stereotactic body radiotherapy for liver cancer.

Daisuke Kawahara1,2, Shuichi Ozawa3, Takeo Nakashima1, Shintaro Tsuda1, Yusuke Ochi1, Takuro Okumura1, Hirokazu Masuda1, Kazunari Hioki1, Tathsuhiko Suzuki2, Yoshimi Ohno1, Tomoki Kimura3, Yuji Murakami3, Yasushi Nagata3.   

Abstract

AIM AND
BACKGROUND: IGRT based on bone matching may produce a large target positioning error in terms of the reproducibility of expiration breath-holding on SBRT for liver cancer. We evaluated the intrafractional and interfractional errors using the diaphragm position at the end of expiration by utilising Abches and analysed the factor of the interfractional error.
MATERIALS AND METHODS: Intrafractional and interfractional errors were measured using a couple of frontal kV images, planning computed tomography (pCT) and daily cone-beam computed tomography (CBCT). Moreover, max-min diaphragm position within daily CBCT image sets with respect to pCT and the maximum value of diaphragm position difference between CBCT and pCT were calculated.
RESULTS: The mean ± SD (standard deviation) of the intra-fraction diaphragm position variation in the frontal kV images was 1.0 ± 0.7 mm in the C-C direction. The inter-fractional diaphragm changes were 0.4 ± 4.6 mm in the C-C direction, 1.4 ± 2.2 mm in the A-P direction, and -0.6 ± 1.8 mm in the L-R direction. There were no significant differences between the maximum value of the max-min diaphragm position within daily CBCT image sets with respect to pCT and the maximum value of diaphragm position difference between CBCT and pCT.
CONCLUSIONS: Residual intrafractional variability of diaphragm position is minimal, but large interfractional diaphragm changes were observed. There was a small effect in the patient condition difference between pCT and CBCT. The impact of the difference in daily breath-holds on the interfractional diaphragm position was large or the difference in daily breath-holding heavily influenced the interfractional diaphragm change.

Entities:  

Keywords:  Breath-hold; IGRT; Interfractional diaphragm changes; SBRT

Year:  2018        PMID: 29463958      PMCID: PMC5814385          DOI: 10.1016/j.rpor.2018.01.007

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  22 in total

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8.  Changes in the respiratory pattern during radiotherapy for cancer in the lung.

Authors:  Geoffrey Hugo; Carlos Vargas; Jian Liang; Larry Kestin; John W Wong; Di Yan
Journal:  Radiother Oncol       Date:  2006-03-27       Impact factor: 6.280

9.  Geometric uncertainties in voluntary deep inspiration breath hold radiotherapy for locally advanced lung cancer.

Authors:  Mirjana Josipovic; Gitte F Persson; Jenny Dueck; Jens Peter Bangsgaard; Gunnar Westman; Lena Specht; Marianne C Aznar
Journal:  Radiother Oncol       Date:  2015-11-26       Impact factor: 6.280

10.  Breathing adapted radiotherapy: a 4D gating software for lung cancer.

Authors:  Nicolas Peguret; Jacqueline Vock; Vincent Vinh-Hung; Pascal Fenoglietto; David Azria; Habib Zaidi; Michael Wissmeyer; Osman Ratib; Raymond Miralbell
Journal:  Radiat Oncol       Date:  2011-06-24       Impact factor: 3.481

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2.  Determination of reproducibility of end-exhaled breath-holding in stereotactic body radiation therapy.

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4.  Impact on liver position under breath-hold by computed tomography contrast agents in stereotactic body radiotherapy of liver cancer.

Authors:  Hideharu Miura; Shuichi Ozawa; Minoru Nakao; Yoshiko Doi; Katsumaro Kubo; Masahiro Kenjo; Yasushi Nagata
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5.  Target coverage of daily cone-beam computed tomography in breath-hold image-guided radiotherapy for gastric lymphoma.

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