Literature DB >> 29458701

Impact of Arterial Stiffness on WatchPAT Variables in Patients With Obstructive Sleep Apnea.

Taku Kinoshita1, Misuzu Yahaba1, Jiro Terada1, Takuma Matsumura1, Yoriko Sakurai1, Kengo Nagashima2, Seiichiro Sakao1, Koichiro Tatsumi1.   

Abstract

STUDY
OBJECTIVES: The WatchPAT is a wrist-worn portable device that creates integration data regarding peripheral arterial tone (PAT), oxyhemoglobin saturation, heart rate, and actigraphy to diagnose or screen for obstructive sleep apnea (OSA). Previous studies have demonstrated the efficacy and validity of respiratory variables measured by the WatchPAT compared to those using polysomnography (PSG). However, the effects of arterial stiffness or atherosclerosis on WatchPAT parameters remain to be elucidated.
METHODS: Sixty-one consecutive patients with suspected OSA who underwent home-based testing with the WatchPAT 200, standard in-laboratory overnight polysomnography (PSG), and pulse wave velocity (PWV) as an index of arterial stiffness were studied. All PSG recordings were scored manually using the American Academy of Sleep Medicine criteria, whereas WatchPAT data were analyzed by an automatic algorithm. We evaluated how arterial stiffness affected respiratory event index data in WatchPAT (WP-AHI), because WP-AHI could be partly influenced by PAT, comparing WP-AHI and the apneahypopnea index measured by PSG (PSG-AHI) in consideration of PWV result.
RESULTS: Overall, WP-AHI was moderately correlated to PSG-AHI, but WP-AHI was significantly lower than PSG-AHI (28.4 ± 19.2 versus 53.6 ± 30.2 events/h, P < .0001). For the lower PWV group, there was a significant correlation and good agreement between the WP-AHI and PSG-AHI, but as the PWV increased, there was low correlation between the WP-AHI and PSG-AHI.
CONCLUSIONS: Arterial stiffness may affect the respiratory variables measured by WatchPAT in patients with OSA. COMMENTARY: A commentary on this article appears in this issue on page 301.
© 2018 American Academy of Sleep Medicine.

Entities:  

Keywords:  WatchPAT; apnea-hypopnea index; arterial stiffness; obstructive sleep apnea; pulse wave velocity

Mesh:

Year:  2018        PMID: 29458701      PMCID: PMC5837833          DOI: 10.5664/jcsm.6970

Source DB:  PubMed          Journal:  J Clin Sleep Med        ISSN: 1550-9389            Impact factor:   4.062


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