Literature DB >> 29443044

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts.

Amanda R Hale1, Ann H Ross2.   

Abstract

The purpose of this paper is to introduce a promising, novel method to aid in the assessment of bone quality in forensically relevant skeletal remains. BMD is an important component of bone's nutritional status and in skeletal remains of both juveniles and adults, and it can provide information about bone quality. For adults remains, it can provide information on pathological conditions or when bone insufficiency may have occurred. In juveniles, it provides a useful metric to elucidate cases of fatal starvation or neglect, which are generally difficult to identify. This paper provides a protocol for the anatomical orientation and analysis of skeletal remains for scanning via dual-energy X-ray absorptiometry (DXA). Three case studies are presented to illustrate when DXA scans can be informative to the forensic practitioner. The first case study presents an individual with observed longitudinal fractures in the weight bearing bones and DXA is used to assess bone insufficiency. BMD is found to be normal suggesting another etiology for the fracture pattern present. The second case study employed DXA to investigate suspected chronic malnutrition. The BMD results are consistent with results from long bone lengths and suggest the juvenile had suffered from chronic malnutrition. The final case study provides an example where fatal starvation in a fourteen-month infant is suspected, which supports autopsy findings of fatal starvation. DXA scans showed low bone mineral density for chronological age and is substantiated by traditional assessments of infant health. However, when dealing with skeletal remains taphonomic alterations should be considered before applying this method.

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Year:  2018        PMID: 29443044      PMCID: PMC5912234          DOI: 10.3791/56713

Source DB:  PubMed          Journal:  J Vis Exp        ISSN: 1940-087X            Impact factor:   1.355


  52 in total

1.  Bone mineral density in malnourished children without rachitic manifestations.

Authors:  Handan Alp; Zerrin Orbak; Tahir Kermen; Hatice Uslu
Journal:  Pediatr Int       Date:  2006-04       Impact factor: 1.524

2.  Association between bone indices assessed by DXA, HR-pQCT and QCT scans in post-menopausal women.

Authors:  Anne Kristine Amstrup; Niels Frederik Breum Jakobsen; Emil Moser; Tanja Sikjaer; Leif Mosekilde; Lars Rejnmark
Journal:  J Bone Miner Metab       Date:  2015-08-21       Impact factor: 2.626

3.  Femur/stature ratio and estimates of stature in children.

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Journal:  Am J Phys Anthropol       Date:  1992-04       Impact factor: 2.868

4.  Technologies for assessment of bone reflecting bone strength and bone mineral density in elderly women: an update.

Authors:  Alvilde Dhainaut; Mari Hoff; Unni Syversen; Glenn Haugeberg
Journal:  Womens Health (Lond)       Date:  2016-02-22

Review 5.  Differences in bone mineral density between normal-weight children and children with overweight and obesity: a systematic review and meta-analysis.

Authors:  J van Leeuwen; B W Koes; W D Paulis; M van Middelkoop
Journal:  Obes Rev       Date:  2017-03-08       Impact factor: 9.213

6.  Age- and sex-dependent cancellous bone changes in a 4000y BP population.

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Journal:  Bone       Date:  1994 Sep-Oct       Impact factor: 4.398

Review 7.  Skeletal and radiological manifestations of child abuse: Implications for study in past populations.

Authors:  Ann H Ross; Chelsey A Juarez
Journal:  Clin Anat       Date:  2016-01-25       Impact factor: 2.414

8.  Long-term precision of DXA scanning assessed over seven years in forty postmenopausal women.

Authors:  R Patel; G M Blake; J Rymer; I Fogelman
Journal:  Osteoporos Int       Date:  2000       Impact factor: 4.507

Review 9.  Imaging methods for bone mass evaluation during childhood and adolescence: an update.

Authors:  Isabela Leite Pezzuti; Adriana Maria Kakehasi; Maria Tereza Filgueiras; Juliana Albano de Guimarães; Isabela Alves Campos de Lacerda; Ivani Novato Silva
Journal:  J Pediatr Endocrinol Metab       Date:  2017-05-01       Impact factor: 1.634

10.  Differences in proximal femur bone density over two centuries.

Authors:  B Lees; T Molleson; T R Arnett; J C Stevenson
Journal:  Lancet       Date:  1993-03-13       Impact factor: 79.321

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  1 in total

1.  Human Bone Proteomes before and after Decomposition: Investigating the Effects of Biological Variation and Taphonomic Alteration on Bone Protein Profiles and the Implications for Forensic Proteomics.

Authors:  Hayley L Mickleburgh; Edward C Schwalbe; Andrea Bonicelli; Haruka Mizukami; Federica Sellitto; Sefora Starace; Daniel J Wescott; David O Carter; Noemi Procopio
Journal:  J Proteome Res       Date:  2021-03-08       Impact factor: 4.466

  1 in total

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