OBJECTIVE: This study examines the differences in bone mineral density between normal-weight children and children with overweight or obesity. METHODS: A systematic review and meta-analysis of observational studies (published up to 22 June 2016) on the differences in bone mineral density between normal-weight children and overweight and obese children was performed. Results were pooled when possible and mean differences (MDs) were calculated between normal-weight and overweight and normal-weight and obese children for bone content and density measures at different body sites. RESULTS: Twenty-seven studies, with a total of 5,958 children, were included. There was moderate and high quality of evidence that overweight (MD 213 g; 95% confidence interval [CI] 166, 261) and obese children (MD 329 g; 95%CI [229, 430]) have a significantly higher whole body bone mineral content than normal-weight children. Similar results were found for whole body bone mineral density. Sensitivity analysis showed that the association was stronger in girls. CONCLUSIONS: Overweight and obese children have a significantly higher bone mineral density compared with normal-weight children. Because there was only one study included with a longitudinal design, the long-term impact of childhood overweight and obesity on bone health at adulthood is not clear.
OBJECTIVE: This study examines the differences in bone mineral density between normal-weight children and children with overweight or obesity. METHODS: A systematic review and meta-analysis of observational studies (published up to 22 June 2016) on the differences in bone mineral density between normal-weight children and overweight and obesechildren was performed. Results were pooled when possible and mean differences (MDs) were calculated between normal-weight and overweight and normal-weight and obesechildren for bone content and density measures at different body sites. RESULTS: Twenty-seven studies, with a total of 5,958 children, were included. There was moderate and high quality of evidence that overweight (MD 213 g; 95% confidence interval [CI] 166, 261) and obesechildren (MD 329 g; 95%CI [229, 430]) have a significantly higher whole body bone mineral content than normal-weight children. Similar results were found for whole body bone mineral density. Sensitivity analysis showed that the association was stronger in girls. CONCLUSIONS: Overweight and obesechildren have a significantly higher bone mineral density compared with normal-weight children. Because there was only one study included with a longitudinal design, the long-term impact of childhood overweight and obesity on bone health at adulthood is not clear.
Authors: Elodie Chaplais; Geraldine Naughton; David Greene; Frederic Dutheil; Bruno Pereira; David Thivel; Daniel Courteix Journal: J Bone Miner Metab Date: 2017-08-04 Impact factor: 2.626
Authors: Lauren F Chun; Elizabeth L Yu; Mary Catherine Sawh; Craig Bross; Jeanne Nichols; Lynda Polgreen; Cynthia Knott; Alexandra Schlein; Claude B Sirlin; Michael S Middleton; Deborah M Kado; Jeffrey B Schwimmer Journal: J Pediatr Date: 2021-02-03 Impact factor: 6.314