Ai-Ru Chia1, Mya-Thway Tint1, Chad Yixian Han2, Ling-Wei Chen3, Marjorelee Colega4, Izzuddin M Aris4, Mei-Chien Chua5, Kok-Hian Tan6,7, Fabian Yap8,7,9, Lynette Pei-Chi Shek3,10, Yap-Seng Chong1,4, Keith M Godfrey11, Marielle V Fortier12, Yung Seng Lee3,4,13, Mary Foong-Fong Chong4,14. 1. Departments of Obstetrics and Gynecology and Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 2. Department of Dietetics and Nutrition, Ng Teng Fong General Hospital, National University Health System, Singapore. 3. Departments of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 4. Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore. 5. Departments of Neonatology, Maternal Fetal Medicine, Pediatrics, and Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore. 6. Departments of Maternal Fetal Medicine, Pediatrics, and Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore. 7. Duke-National University of Singapore Graduate Medical School, Singapore. 8. Departments of Pediatrics, and Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore. 9. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. 10. Divisions of Pediatric Allergy, Immunology, and Rheumatology and Pediatric Endocrinology and Diabetes, Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore. 11. Medical Research Council Lifecourse Epidemiology Unit and National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom. 12. Departments of Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore. 13. Divisions of Pediatric Endocrinology and Diabetes, Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore. 14. Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Abstract
Background: Evidence linking maternal diet quality during pregnancy with infant birth outcomes is limited in Asia. Objective: We investigated the association of maternal diet quality with the risk of preterm birth, offspring birth size, and adiposity in a multiethnic Asian birth cohort. Design: Dietary intakes of 1051 pregnant women were ascertained at 26-28 wk of gestation with the use of 24-h recalls and 3-d food diaries, from which diet quality (score range: 0-100) was measured by the Healthy Eating Index for pregnant women in Singapore (HEI-SGP). Gestational age was established by first-trimester ultrasound dating scan. Neonatal weight and length were measured at birth. Body composition was assessed by air displacement plethysmography in a subset of infants (n = 313) within 72 h after birth, and abdominal adiposity was assessed by MRI (n = 316) within the first 2 wk of life. Associations were assessed by multivariable linear regression for continuous outcomes and logistic regression for preterm birth. Results: The mean ± SD maternal HEI-SGP score was 52.1 ± 13.6. Maternal diet quality during pregnancy was not associated with preterm birth or birth weight. Greater adherence to the HEI-SGP (per 10-point increment in HEI-SGP score) was associated with longer birth length [β (95% CI): 0.14 (0.03, 0.24 cm)], lower body mass index (in kg/m2) at birth [-0.07 (-0.13, -0.01)], lower sum of triceps and subscapular skinfold thickness [-0.15 (-0.26, -0.05 mm)], lower percentage body fat [-0.52% (-0.84%, -0.20%)], lower fat mass [-17.23 (-29.52, -4.94 g)], lower percentage abdominal superficial subcutaneous adipose tissue [-0.16% (-0.30%, -0.01%)], and lower percentage deep subcutaneous adipose tissue [-0.06% (-0.10%, -0.01%)]. Conclusions: Higher maternal diet quality during pregnancy was associated with longer birth length and lower neonatal adiposity but not with birth weight and preterm birth. These findings warrant further investigation in independent studies. This trial was registered at clinicaltrials.gov as NCT01174875.
Background: Evidence linking maternal diet quality during pregnancy with infant birth outcomes is limited in Asia. Objective: We investigated the association of maternal diet quality with the risk of preterm birth, offspring birth size, and adiposity in a multiethnic Asian birth cohort. Design: Dietary intakes of 1051 pregnant women were ascertained at 26-28 wk of gestation with the use of 24-h recalls and 3-d food diaries, from which diet quality (score range: 0-100) was measured by the Healthy Eating Index for pregnant women in Singapore (HEI-SGP). Gestational age was established by first-trimester ultrasound dating scan. Neonatal weight and length were measured at birth. Body composition was assessed by air displacement plethysmography in a subset of infants (n = 313) within 72 h after birth, and abdominal adiposity was assessed by MRI (n = 316) within the first 2 wk of life. Associations were assessed by multivariable linear regression for continuous outcomes and logistic regression for preterm birth. Results: The mean ± SD maternal HEI-SGP score was 52.1 ± 13.6. Maternal diet quality during pregnancy was not associated with preterm birth or birth weight. Greater adherence to the HEI-SGP (per 10-point increment in HEI-SGP score) was associated with longer birth length [β (95% CI): 0.14 (0.03, 0.24 cm)], lower body mass index (in kg/m2) at birth [-0.07 (-0.13, -0.01)], lower sum of triceps and subscapular skinfold thickness [-0.15 (-0.26, -0.05 mm)], lower percentage body fat [-0.52% (-0.84%, -0.20%)], lower fat mass [-17.23 (-29.52, -4.94 g)], lower percentage abdominal superficial subcutaneous adipose tissue [-0.16% (-0.30%, -0.01%)], and lower percentage deep subcutaneous adipose tissue [-0.06% (-0.10%, -0.01%)]. Conclusions: Higher maternal diet quality during pregnancy was associated with longer birth length and lower neonatal adiposity but not with birth weight and preterm birth. These findings warrant further investigation in independent studies. This trial was registered at clinicaltrials.gov as NCT01174875.
Authors: Neena Modi; E Louise Thomas; Sabita N Uthaya; Shalini Umranikar; Jimmy D Bell; Chittaranjan Yajnik Journal: Pediatr Res Date: 2009-05 Impact factor: 3.756
Authors: Izzuddin M Aris; Mihir Gandhi; Yin Bun Cheung; Shu E Soh; Mya Thway Tint; Peter D Gluckman; Yung Seng Lee; Fabian K P Yap; Yap Seng Chong Journal: Ann Acad Med Singapore Date: 2014-09 Impact factor: 2.473
Authors: Sheryl L Rifas-Shiman; Janet W Rich-Edwards; Walter C Willett; Ken P Kleinman; Emily Oken; Matthew W Gillman Journal: Paediatr Perinat Epidemiol Date: 2006-01 Impact factor: 3.980
Authors: Neena Modi; Dominika Murgasova; Rikke Ruager-Martin; E Louise Thomas; Matthew J Hyde; Christopher Gale; Shalini Santhakumaran; Caroline J Doré; Afshin Alavi; Jimmy D Bell Journal: Pediatr Res Date: 2011-09 Impact factor: 3.756
Authors: Mary Foong-Fong Chong; Ai-Ru Chia; Marjorelee Colega; Mya-Thway Tint; Izzuddin M Aris; Yap-Seng Chong; Peter Gluckman; Keith M Godfrey; Kenneth Kwek; Seang-Mei Saw; Fabian Yap; Rob M van Dam; Yung Seng Lee Journal: J Nutr Date: 2015-05-06 Impact factor: 4.798
Authors: I M Aris; S E Soh; M T Tint; S Liang; A Chinnadurai; S M Saw; K Kwek; K M Godfrey; P D Gluckman; Y S Chong; F K P Yap; Y S Lee Journal: Eur J Clin Nutr Date: 2013-04-03 Impact factor: 4.016
Authors: Ling-Wei Chen; Mya-Thway Tint; Marielle V Fortier; Izzuddin M Aris; Jonathan Y Bernard; Marjorelee Colega; Peter D Gluckman; Seang-Mei Saw; Yap-Seng Chong; Fabian Yap; Keith M Godfrey; Michael S Kramer; Rob M van Dam; Mary Foong-Fong Chong; Yung Seng Lee Journal: J Nutr Date: 2016-07-06 Impact factor: 4.798
Authors: Ling-Jun Li; Peng Guan Ong; Marjorelee T Colega; Chad Yixian Han; Ling Wei Chen; Ryan Man Eyn Kidd; Ecosse Lamoureux; Peter Gluckman; Kenneth Kwek; Yap Seng Chong; Seang Mei Saw; Keith M Godfrey; Tien Yin Wong; Mary Chong Foong-Fong Journal: PLoS One Date: 2016-08-10 Impact factor: 3.240
Authors: Meghana D Gadgil; Samantha F Ehrlich; Yeyi Zhu; Susan D Brown; Monique M Hedderson; Yvonne Crites; Assiamira Ferrara Journal: J Womens Health (Larchmt) Date: 2018-10-30 Impact factor: 2.681
Authors: Ai-Ru Chia; Ling-Wei Chen; Jun Shi Lai; Chun Hong Wong; Nithya Neelakantan; Rob Martinus van Dam; Mary Foong-Fong Chong Journal: Adv Nutr Date: 2019-07-01 Impact factor: 8.701
Authors: See Ling Loy; Yin Bun Cheung; Marjorelee T Colega; Airu Chia; Chad Yixian Han; Keith M Godfrey; Yap-Seng Chong; Lynette Pei-Chi Shek; Kok Hian Tan; Ngee Lek; Jerry Kok Yen Chan; Mary Foong-Fong Chong; Fabian Yap Journal: Nutrients Date: 2019-11-06 Impact factor: 5.717
Authors: Neda Mortaji; John E Krzeczkowski; Khrista Boylan; Linda Booij; Maude Perreault; Ryan J Van Lieshout Journal: Am J Clin Nutr Date: 2021-10-04 Impact factor: 8.472
Authors: Yu Ni; Adam Szpiro; Christine Loftus; Frances Tylavsky; Mario Kratz; Nicole R Bush; Kaja Z LeWinn; Sheela Sathyanarayana; Daniel A Enquobahrie; Robert Davis; Annette L Fitzpatrick; Jennifer Sonney; Qi Zhao; Catherine J Karr Journal: J Nutr Date: 2021-04-08 Impact factor: 4.687
Authors: Susanne Strohmaier; Leonie Helen Bogl; A Heather Eliassen; Jennifer Massa; Alison E Field; Jorge E Chavarro; Ming Ding; Rulla M Tamimi; Eva Schernhammer Journal: Eur J Epidemiol Date: 2020-03-17 Impact factor: 8.082