Literature DB >> 29374573

Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.

Parul H Kothari1, Weiliang Qiu2, Damien C Croteau-Chonka2, Fernando D Martinez3, Andrew H Liu4, Robert F Lemanske5, Carole Ober6, Jerry A Krishnan7, Dan L Nicolae8, Kathleen C Barnes9, Stephanie J London10, Albino Barraza-Villarreal11, Steven R White12, Edward T Naureckas12, Joshua Millstein13, W James Gauderman13, Frank D Gilliland14, Vincent J Carey2, Scott T Weiss15, Benjamin A Raby16.   

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Year:  2018        PMID: 29374573      PMCID: PMC5994185          DOI: 10.1016/j.jaci.2017.11.057

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


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  9 in total

1.  Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

Authors:  Michaela Schedel; Sven Michel; Vincent D Gaertner; Antoaneta A Toncheva; Martin Depner; Aristea Binia; Maximilian Schieck; Marie T Rieger; Norman Klopp; Andrea von Berg; Albrecht Bufe; Otto Laub; Ernst Rietschel; Andrea Heinzmann; Burkard Simma; Christian Vogelberg; Jon Genuneit; Thomas Illig; Michael Kabesch
Journal:  J Allergy Clin Immunol       Date:  2015-04-28       Impact factor: 10.793

2.  17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry.

Authors:  James H Flory; Patrick M Sleiman; Jason D Christie; Kiran Annaiah; Jonathan Bradfield; Cecilia E Kim; Joseph Glessner; Marcin Imielinski; Hongzhe Li; Edward C Frackelton; Hou Cuiping; George Otieno; Kelly Thomas; Ryan Smith; Wendy Glaberson; Maria Garris; Rosetta Chiavacci; Julian Allen; Jonathan Spergel; Robert Grundmeier; Michael Grunstein; Michael Magnusson; Struan F A Grant; Klaus Bønnelykke; Hans Bisgaard; Hakon Hakonarson
Journal:  J Allergy Clin Immunol       Date:  2009-08-05       Impact factor: 10.793

3.  Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.

Authors:  Dominique J Verlaan; Soizik Berlivet; Gary M Hunninghake; Anne-Marie Madore; Mathieu Larivière; Sanny Moussette; Elin Grundberg; Tony Kwan; Manon Ouimet; Bing Ge; Rose Hoberman; Marcin Swiatek; Joana Dias; Kevin C L Lam; Vonda Koka; Eef Harmsen; Manuel Soto-Quiros; Lydiana Avila; Juan C Celedón; Scott T Weiss; Ken Dewar; Daniel Sinnett; Catherine Laprise; Benjamin A Raby; Tomi Pastinen; Anna K Naumova
Journal:  Am J Hum Genet       Date:  2009-09       Impact factor: 11.025

4.  Disease variants alter transcription factor levels and methylation of their binding sites.

Authors:  Marc Jan Bonder; René Luijk; Daria V Zhernakova; Matthijs Moed; Patrick Deelen; Martijn Vermaat; Maarten van Iterson; Freerk van Dijk; Michiel van Galen; Jan Bot; Roderick C Slieker; P Mila Jhamai; Michael Verbiest; H Eka D Suchiman; Marijn Verkerk; Ruud van der Breggen; Jeroen van Rooij; Nico Lakenberg; Wibowo Arindrarto; Szymon M Kielbasa; Iris Jonkers; Peter van 't Hof; Irene Nooren; Marian Beekman; Joris Deelen; Diana van Heemst; Alexandra Zhernakova; Ettje F Tigchelaar; Morris A Swertz; Albert Hofman; André G Uitterlinden; René Pool; Jenny van Dongen; Jouke J Hottenga; Coen D A Stehouwer; Carla J H van der Kallen; Casper G Schalkwijk; Leonard H van den Berg; Erik W van Zwet; Hailiang Mei; Yang Li; Mathieu Lemire; Thomas J Hudson; P Eline Slagboom; Cisca Wijmenga; Jan H Veldink; Marleen M J van Greevenbroek; Cornelia M van Duijn; Dorret I Boomsma; Aaron Isaacs; Rick Jansen; Joyce B J van Meurs; Peter A C 't Hoen; Lude Franke; Bastiaan T Heijmans
Journal:  Nat Genet       Date:  2016-12-05       Impact factor: 38.330

5.  Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control.

Authors:  Damien C Croteau-Chonka; Weiliang Qiu; Fernando D Martinez; Robert C Strunk; Robert F Lemanske; Andrew H Liu; Frank D Gilliland; Joshua Millstein; W James Gauderman; Carole Ober; Jerry A Krishnan; Steven R White; Edward T Naureckas; Dan L Nicolae; Kathleen C Barnes; Stephanie J London; Albino Barraza-Villarreal; Vincent J Carey; Scott T Weiss; Benjamin A Raby
Journal:  Am J Respir Crit Care Med       Date:  2017-01-15       Impact factor: 21.405

6.  cit: hypothesis testing software for mediation analysis in genomic applications.

Authors:  Joshua Millstein; Gary K Chen; Carrie V Breton
Journal:  Bioinformatics       Date:  2016-03-09       Impact factor: 6.937

7.  Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.

Authors:  Minal Calışkan; Yury A Bochkov; Eskil Kreiner-Møller; Klaus Bønnelykke; Michelle M Stein; Gaixin Du; Hans Bisgaard; Daniel J Jackson; James E Gern; Robert F Lemanske; Dan L Nicolae; Carole Ober
Journal:  N Engl J Med       Date:  2013-03-27       Impact factor: 91.245

8.  A large-scale, consortium-based genomewide association study of asthma.

Authors:  Miriam F Moffatt; Ivo G Gut; Florence Demenais; David P Strachan; Emmanuelle Bouzigon; Simon Heath; Erika von Mutius; Martin Farrall; Mark Lathrop; William O C M Cookson
Journal:  N Engl J Med       Date:  2010-09-23       Impact factor: 91.245

9.  Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus.

Authors:  Nathalie Acevedo; Lovisa E Reinius; Dario Greco; Anna Gref; Christina Orsmark-Pietras; Helena Persson; Göran Pershagen; Gunilla Hedlin; Erik Melén; Annika Scheynius; Juha Kere; Cilla Söderhäll
Journal:  Hum Mol Genet       Date:  2014-09-25       Impact factor: 6.150

  9 in total
  9 in total

1.  Why Is ORMDL3 on Chromosome 17q21 Highly Linked to Asthma?

Authors:  Marina Miller; David H Broide
Journal:  Am J Respir Crit Care Med       Date:  2019-02-15       Impact factor: 21.405

Review 2.  Orm/ORMDL proteins: Gate guardians and master regulators.

Authors:  Deanna Davis; Muthukumar Kannan; Binks Wattenberg
Journal:  Adv Biol Regul       Date:  2018-08-31

3.  The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.

Authors:  Nincy Debeuf; Assem Zhakupova; Regula Steiner; Sofie Van Gassen; Kim Deswarte; Farzaneh Fayazpour; Justine Van Moorleghem; Karl Vergote; Benjamin Pavie; Kelly Lemeire; Hamida Hammad; Thorsten Hornemann; Sophie Janssens; Bart N Lambrecht
Journal:  J Allergy Clin Immunol       Date:  2019-07-20       Impact factor: 10.793

4.  Asthma Susceptibility Gene ORMDL3 Promotes Autophagy in Human Bronchial Epithelium.

Authors:  Feng Guo; Yuan Hao; Li Zhang; Damien C Croteau-Chonka; Derek Thibault; Parul Kothari; Lijia Li; Bruce D Levy; Xiaobo Zhou; Benjamin A Raby
Journal:  Am J Respir Cell Mol Biol       Date:  2022-06       Impact factor: 7.748

Review 5.  ORMDL3 and allergic asthma: From physiology to pathology.

Authors:  Briana James; Sheldon Milstien; Sarah Spiegel
Journal:  J Allergy Clin Immunol       Date:  2019-07-31       Impact factor: 10.793

Review 6.  Transgenerational and intergenerational epigenetic inheritance in allergic diseases.

Authors:  Toril Mørkve Knudsen; Faisal I Rezwan; Yu Jiang; Wilfried Karmaus; Cecilie Svanes; John W Holloway
Journal:  J Allergy Clin Immunol       Date:  2018-07-21       Impact factor: 10.793

7.  Epigenome-wide association study of asthma and wheeze characterizes loci within HK1.

Authors:  Todd M Everson; Hongmei Zhang; Gabrielle A Lockett; Akhilesh Kaushal; Melinda Forthofer; Susan L Ewart; Kimberley Burrows; Caroline L Relton; Gemma C Sharp; A John Henderson; Veeresh K Patil; Faisal I Rezwan; S Hasan Arshad; John W Holloway; Wilfried Karmaus
Journal:  Allergy Asthma Clin Immunol       Date:  2019-07-24       Impact factor: 3.406

8.  Diversity and the Splice of Life: Mapping the 17q12-21.1 Locus for Variants Associated with Early-Onset Asthma in African American Individuals.

Authors:  Benjamin A Raby; Scott T Weiss
Journal:  Am J Respir Crit Care Med       Date:  2021-02-15       Impact factor: 21.405

9.  Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci.

Authors:  Alexander D Clark; Nisha Nair; Amy E Anderson; Nishanthi Thalayasingam; Najib Naamane; Andrew J Skelton; Julie Diboll; Anne Barton; Stephen Eyre; John D Isaacs; Arthur G Pratt; Louise N Reynard
Journal:  J Allergy Clin Immunol       Date:  2020-01-13       Impact factor: 10.793

  9 in total

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