Literature DB >> 293665

Purification and partial characterization of human lymphoblast interferon.

K C Zoon, M E Smith, P J Bridgen, D zur Nedden, C B Anfinsen.   

Abstract

One component of human lymphoblastoid interferon obtained from Namalwa cultures induced by Newcastle disease virus has been purified to a specific activity of 2.5 x 10(8) interferon units per mg of protein (protein content based on amino acid analysis). A single polypeptide species with an apparent molecular weight of 18,500 comigrating with the antiviral activity was observed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. Preliminary amino-terminal sequencing results support the conclusion that the interferon species is essentially homogeneous.

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Year:  1979        PMID: 293665      PMCID: PMC411697          DOI: 10.1073/pnas.76.11.5601

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  28 in total

1.  The thiobarbituric acid assay of sialic acids.

Authors:  L WARREN
Journal:  J Biol Chem       Date:  1959-08       Impact factor: 5.157

2.  THE EXTRACELLULAR GLYCOSIDASES OF DIPLOCOCCUS PNEUMONIAE. I. PURIFICATION AND PROPERTIES OF A NEURAMINIDASE AND A BETA-GALACTOSIDASE. ACTION ON THE ALPHA-1-ACID GLYCOPROTEIN OF HUMAN PLASMA.

Authors:  R C HUGHES; R W JEANLOZ
Journal:  Biochemistry       Date:  1964-10       Impact factor: 3.162

3.  THE EXTRACELLULAR GLYCOSIDASES OF DIPLOCOCCUS PNEUMONIAE. II. PURIFICATION AND PROPERTIES OF A BETA-N-ACETYLGLUCOSAMINIDASE. ACTION ON A DERIVATIVE ON THE ALPHA-1-ACID GLYCOPROTEIN OF HUMAN PLASMA.

Authors:  R C HUGHES; R W JEANLOZ
Journal:  Biochemistry       Date:  1964-10       Impact factor: 3.162

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Production of human lymphoblastoid interferon by Namalva cells.

Authors:  K C Zoon; C E Buckler; P J Bridgen; D Gurari-Rotman
Journal:  J Clin Microbiol       Date:  1978-01       Impact factor: 5.948

6.  Large-scale production and concentration of human lymphoid interferon.

Authors:  F Klein; R T Ricketts; W I Jones; I A DeArmon; M J Temple; K C Zoon; P J Bridgen
Journal:  Antimicrob Agents Chemother       Date:  1979-03       Impact factor: 5.191

7.  Purification of interferon from mouse Ehrlich ascites tumor cells.

Authors:  M Kawakita; B Cabrer; H Taira; M Rebello; E Slattery; H Weideli; P Lengyel
Journal:  J Biol Chem       Date:  1978-01-25       Impact factor: 5.157

8.  Human leukocyte interferon: production, purification to homogeneity, and initial characterization.

Authors:  M Rubinstein; S Rubinstein; P C Familletti; R S Miller; A A Waldman; S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

9.  Purification of mouse L cell interferon. Essentially pure preparations with associated cell growth inhibitory activity.

Authors:  Y Iwakura; S Yonehara; Y Kawade
Journal:  J Biol Chem       Date:  1978-07-25       Impact factor: 5.157

10.  The isolation and amino acid/sugar composition of human fibroblastoid interferon.

Authors:  Y H Tan; F Barakat; W Berthold; H Smith-Johannsen; C Tan
Journal:  J Biol Chem       Date:  1979-08-25       Impact factor: 5.157

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  16 in total

1.  Spontaneous production of human interferon.

Authors:  L A Pickering; L H Kronenberg; W E Stewart
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

Review 2.  The interferon renaissance: molecular aspects of induction and action.

Authors:  J Gordon; M A Minks
Journal:  Microbiol Rev       Date:  1981-06

3.  Biologic activity in a fragment of recombinant human interferon alpha.

Authors:  S K Ackerman; D Zur Nedden; M Heintzelman; M Hunkapiller; K Zoon
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

4.  Elevated levels of (2'-5')oligoadenylic acid polymerase activity in growth-arrested human lymphoblastoid Namalva cells.

Authors:  I Krishnan; C Baglioni
Journal:  Mol Cell Biol       Date:  1981-10       Impact factor: 4.272

5.  Multiple biological activities of homogeneous human alpha interferon.

Authors:  A M Attallah; K Zoon; T Folks; J Huntington; T J Yeatman
Journal:  Infect Immun       Date:  1981-12       Impact factor: 3.441

6.  Membrane ultrafiltration: concentration of interleukin-3.

Authors:  F Klein; R T Ricketts; T R Rohrer; W I Jones; P M Clark; M C Flickinger
Journal:  Appl Environ Microbiol       Date:  1984-05       Impact factor: 4.792

Review 7.  Induction of type I interferon by RNA viruses: cellular receptors and their substrates.

Authors:  Alina Baum; Adolfo García-Sastre
Journal:  Amino Acids       Date:  2009-11-01       Impact factor: 3.520

8.  Sepharose-immobilized triazine dyes as adsorbants for human lymphoblastoid interferon purification.

Authors:  P J Neame; I Parikh
Journal:  Appl Biochem Biotechnol       Date:  1982-07       Impact factor: 2.926

9.  Unusual apparently constitutive interferons and antagonists in human placental blood.

Authors:  P Duc-Goiran; B Robert-Galliot; J Lopez; C Chany
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

10.  Selective production of interferon-alpha subtypes by cultured peripheral blood mononuclear cells and lymphoblastoid cell lines.

Authors:  A L Greenway; M L Overall; N Sattayasai; M J Rowley; P J Hertzog; G L McMullen; B F Cheetham; S Marzuki
Journal:  Immunology       Date:  1992-01       Impact factor: 7.397

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