Literature DB >> 6430227

Membrane ultrafiltration: concentration of interleukin-3.

F Klein, R T Ricketts, T R Rohrer, W I Jones, P M Clark, M C Flickinger.   

Abstract

A pilot-plant-scale operation was used for studying membrane ultrafiltration and concentration of kiloliter quantities of the lymphokine interleukin-3 with a single set of membranes. Initial use of ammonium sulfate precipitation of interleukin-3 proved erratic in the recovery of biological activity and resulted in corrosion of the processing equipment. Membrane ultrafiltration proved to be effective in enabling control of the degree of concentration and predicting recovery of the biologically active protein.

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Year:  1984        PMID： 6430227      PMCID： PMC240045          DOI： 10.1128/aem.47.5.1023-1026.1984

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  14 in total

1.  Arenavirus concentration by molecular filtration.

Authors:  J D Gangemi; E V Connell; B G Mahlandt; G A Eddy
Journal:  Appl Environ Microbiol       Date:  1977-09       Impact factor: 4.792

2.  In vitro synthesis of messenger RNA by a defective interfering particle of vesicular stomatitis virus.

Authors:  R J Colonno; R A Lazzarini; J D Keene; A K Banerjee
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

3.  Enteric viruses in renovated water in Manitoba.

Authors:  L Sekla; W Stackiw; C Kay; L VanBuckenhout
Journal:  Can J Microbiol       Date:  1980-04       Impact factor: 2.419

4.  Purification and partial characterization of human lymphoblast interferon.

Authors:  K C Zoon; M E Smith; P J Bridgen; D zur Nedden; C B Anfinsen
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

5.  Large-scale production and concentration of human lymphoid interferon.

Authors:  F Klein; R T Ricketts; W I Jones; I A DeArmon; M J Temple; K C Zoon; P J Bridgen
Journal:  Antimicrob Agents Chemother       Date:  1979-03       Impact factor: 5.191

6.  Procedures fo large-scale production and concentration of lymphoblastoid interferon.

Authors:  F Klein; R T Ricketts
Journal:  Methods Enzymol       Date:  1981       Impact factor: 1.600

7.  Concentration of poliovirus in water by molecular filtration.

Authors:  D Berman; M E Rohr; R S Safferman
Journal:  Appl Environ Microbiol       Date:  1980-08       Impact factor: 4.792

8.  Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from athymic mice by a unique lymphokine.

Authors:  J N Ihle; L Pepersack; L Rebar
Journal:  J Immunol       Date:  1981-06       Impact factor: 5.422

9.  Large scale isolation of human erythrocyte membranes by high volume molecular filtration.

Authors:  T L Rosenberry; J F Chen; M M Lee; T A Moulton; P Onigman
Journal:  J Biochem Biophys Methods       Date:  1981-01

10.  Purification of infectious feline leukemia virus from large volumes of tissue culture fluids.

Authors:  L E Mathes; D S Yohn; R G Olsen
Journal:  J Clin Microbiol       Date:  1977-03       Impact factor: 5.948
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