Victor M Salinas-Torres1, Rafael A Salinas-Torres2, Ricardo M Cerda-Flores3, Laura E Martínez-de-Villarreal4. 1. Universidad Autónoma de Nuevo León, Departamento de Genética, Facultad de Medicina y Hospital Universitario José Eleuterio González, Monterrey, Nuevo León, México; Instituto de Servicios de Salud Pública en el Estado de Baja California, Departamento de Genética, Hospital General Tijuana, Tijuana, Baja California, México. Electronic address: vm_salinas7@hotmail.com. 2. Instituto de Servicios de Salud Pública en el Estado de Baja California, Departamento de Genética, Hospital General Tijuana, Tijuana, Baja California, México; Instituto Tecnológico de Tijuana, Departamento de Sistemas y Computación, Tijuana, Baja California, México. 3. Universidad Autónoma de Nuevo León, Facultad de Enfermería, Monterrey, Nuevo León, México. 4. Universidad Autónoma de Nuevo León, Departamento de Genética, Facultad de Medicina y Hospital Universitario José Eleuterio González, Monterrey, Nuevo León, México.
Abstract
STUDY OBJECTIVE: To explore the prevalence, mortality, and spatial distribution of gastroschisis using a large population-based sample with cases identified according to birth and death certificates (ICD-10 diagnosis code Q79.3, gastroschisis) through the General Directorate of Health Information of the Secretary Health of Mexico, over the course of a 15-year period. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: A descriptive study examining 10,287 cases of gastroschisis was performed from 2000-2014 using public natality data for denominators (more than 25 million live births). Gastroschisis prevalence and mortality was calculated for each of year, state, maternal, and newborn characteristics. Spatial distribution was analyzed according to gastroschisis prevalence in the 32 states of Mexico. RESULTS: Gastroschisis prevalence was 4.01 per 10,000 live births (annual trend 2.09-6.85). Mortality associated with gastroschisis was 1.28 per 10,000 live births. Women younger than 20 years old, primiparae, and preterm infants had the highest gastroschisis-related prevalence (13.12, 5.83, and 7.51 per 10,000 live births, respectively). Gastroschisis prevalence and mortality did not differ according to newborn sex. A negative binomial distribution, variance (82,391.87) greater than the mean (321.47) was identified. CONCLUSION: Our findings show an increasing temporal trend for gastroschisis since 2000 in Mexico. Additionally, gastroschisis might follow in future instances a positive binomial or Poisson distribution. Therefore, improving surveillance of risk factors and supporting research for gastroschisis is warranted among maternal age younger than 25, particularly, younger than 20 years of age.
STUDY OBJECTIVE: To explore the prevalence, mortality, and spatial distribution of gastroschisis using a large population-based sample with cases identified according to birth and death certificates (ICD-10 diagnosis code Q79.3, gastroschisis) through the General Directorate of Health Information of the Secretary Health of Mexico, over the course of a 15-year period. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: A descriptive study examining 10,287 cases of gastroschisis was performed from 2000-2014 using public natality data for denominators (more than 25 million live births). Gastroschisis prevalence and mortality was calculated for each of year, state, maternal, and newborn characteristics. Spatial distribution was analyzed according to gastroschisis prevalence in the 32 states of Mexico. RESULTS: Gastroschisis prevalence was 4.01 per 10,000 live births (annual trend 2.09-6.85). Mortality associated with gastroschisis was 1.28 per 10,000 live births. Women younger than 20 years old, primiparae, and preterm infants had the highest gastroschisis-related prevalence (13.12, 5.83, and 7.51 per 10,000 live births, respectively). Gastroschisis prevalence and mortality did not differ according to newborn sex. A negative binomial distribution, variance (82,391.87) greater than the mean (321.47) was identified. CONCLUSION: Our findings show an increasing temporal trend for gastroschisis since 2000 in Mexico. Additionally, gastroschisis might follow in future instances a positive binomial or Poisson distribution. Therefore, improving surveillance of risk factors and supporting research for gastroschisis is warranted among maternal age younger than 25, particularly, younger than 20 years of age.
Authors: Victor M Salinas-Torres; Rafael A Salinas-Torres; Ricardo M Cerda-Flores; Hugo L Gallardo-Blanco; Laura E Martínez-de-Villarreal Journal: Pediatr Surg Int Date: 2018-08-09 Impact factor: 1.827
Authors: Pastor Escarcega-Fujigaki; Guillermo Hernandez-Peredo-Rezk; Naomi J Wright; Ahtziri Del Carmen Cardenas-Paniagua; Haydee Velez-Blanco; Celine Gutierrez-Canencia; Lorenzo Saavedra-Velez; Berenice Venegas-Espinoza; Jose Luis Diaz-Luna; Miguel Castro-Ramirez Journal: World J Surg Date: 2021-10-21 Impact factor: 3.352
Authors: Víctor M Salinas-Torres; Hugo L Gallardo-Blanco; Rafael A Salinas-Torres; Ricardo M Cerda-Flores; José J Lugo-Trampe; Daniel Z Villarreal-Martínez; Laura E Martínez de Villarreal Journal: Int J Mol Sci Date: 2019-05-09 Impact factor: 5.923
Authors: Víctor M Salinas-Torres; Hugo L Gallardo-Blanco; Rafael A Salinas-Torres; Ricardo M Cerda-Flores; José J Lugo-Trampe; Daniel Z Villarreal-Martínez; Marisol Ibarra-Ramírez; Laura E Martínez de Villarreal Journal: Mol Genet Genomic Med Date: 2020-03-12 Impact factor: 2.183