Pastor Escarcega-Fujigaki1, Guillermo Hernandez-Peredo-Rezk2, Naomi J Wright3, Ahtziri Del Carmen Cardenas-Paniagua4, Haydee Velez-Blanco5, Celine Gutierrez-Canencia6, Lorenzo Saavedra-Velez5, Berenice Venegas-Espinoza7, Jose Luis Diaz-Luna4, Miguel Castro-Ramirez8. 1. Department of Pediatric Surgery, Centro de Alta Especialidad Dr. Rafael Lucio, Av Adolfo Ruiz Rortines 2903, col. Unidad Magisterial, Xalapa, Veracruz, Mexico. drpastor_ef@yahoo.com. 2. Department of Pediatric Surgery, Centro de Alta Especialidad Dr. Rafael Lucio, Av Adolfo Ruiz Rortines 2903, col. Unidad Magisterial, Xalapa, Veracruz, Mexico. 3. King's Centre for Global Health and Health Partnerships, School of Population Health and Environmental Sciences, King's College London, London, UK. 4. Department of Medical Pediatrics, Centro de Alta Especialidad Dr. Rafael Lucio, Xalapa, Veracruz, Mexico. 5. Department of Neonatology, Centro de Alta Especialidad Dr. Rafael Lucio, Xalapa, Veracruz, Mexico. 6. Department of Radiology, Centro de Alta Especialidad Dr. Rafael Lucio, Xalapa, Veracruz, Mexico. 7. Department of Gynecology, Centro de Alta Especialidad Dr. Rafael Lucio, Xalapa, Veracruz, Mexico. 8. Department of Anesthesiology, Centro de Alta Especialidad Dr. Rafael Lucio, Xalapa, Veracruz, Mexico.
Abstract
BACKGROUND: This research adopted a care protocol from high-income countries in a level II/III hospital in a middle-income country to decrease morbidity and mortality associated with gastroschisis. METHODS: We established a multidisciplinary protocol to treat patients with gastroschisis prospectively from November 2012 to November 2018. This included prenatal diagnosis, presence of a neonatologist and pediatric surgeon at birth, and either performing primary closure on the patients with an Apgar score of 8/9, mild serositis, and no breathing difficulty or placing a preformed silo, when unable to fulfill these criteria, under sedation and analgesia (no intubation) in the operating room or at the patients' bedside. The subsequent management took place in the neonatal intensive care unit. The data were analyzed through the Mann-Whitney and Student's t-distribution for the two independent samples; the categorical variables were analyzed through a chi-square distribution or Fisher's exact test. RESULTS: In total, 55 patients were included in the study: 33 patients (60%) were managed with a preformed silo, whereas 22 patients (40%) underwent primary closure. Prenatal diagnosis (P = 0.02), birth at the main hospital (P = 0.02), and the presence of a pediatric surgeon at birth (P = 0.04) were associated with successful primary closure. The primary closure group had fewer fasting days (P < 0.001) and a shorter neonatal intensive care unit length of stay (P = 0.025). The survival rate was 92.7% (51 patients). CONCLUSION: The treatment model modified to fit the means of our hospital proved successful.
BACKGROUND: This research adopted a care protocol from high-income countries in a level II/III hospital in a middle-income country to decrease morbidity and mortality associated with gastroschisis. METHODS: We established a multidisciplinary protocol to treat patients with gastroschisis prospectively from November 2012 to November 2018. This included prenatal diagnosis, presence of a neonatologist and pediatric surgeon at birth, and either performing primary closure on the patients with an Apgar score of 8/9, mild serositis, and no breathing difficulty or placing a preformed silo, when unable to fulfill these criteria, under sedation and analgesia (no intubation) in the operating room or at the patients' bedside. The subsequent management took place in the neonatal intensive care unit. The data were analyzed through the Mann-Whitney and Student's t-distribution for the two independent samples; the categorical variables were analyzed through a chi-square distribution or Fisher's exact test. RESULTS: In total, 55 patients were included in the study: 33 patients (60%) were managed with a preformed silo, whereas 22 patients (40%) underwent primary closure. Prenatal diagnosis (P = 0.02), birth at the main hospital (P = 0.02), and the presence of a pediatric surgeon at birth (P = 0.04) were associated with successful primary closure. The primary closure group had fewer fasting days (P < 0.001) and a shorter neonatal intensive care unit length of stay (P = 0.025). The survival rate was 92.7% (51 patients). CONCLUSION: The treatment model modified to fit the means of our hospital proved successful.
Authors: Victor M Salinas-Torres; Rafael A Salinas-Torres; Ricardo M Cerda-Flores; Laura E Martínez-de-Villarreal Journal: J Pediatr Adolesc Gynecol Date: 2018-01-06 Impact factor: 1.814
Authors: Kyle N Cowan; Pramod S Puligandla; Jean-Martin Laberge; Erik D Skarsgard; Sarah Bouchard; Natalie Yanchar; Peter Kim; Shoo Lee; Douglas McMillan; Peter von Dadelszen Journal: J Pediatr Surg Date: 2012-06 Impact factor: 2.545