Literature DB >> 29298289

Organoids required! A new path to understanding human brain development and disease.

Paola Arlotta1.   

Abstract

Our ability to study the developing human brain has recently been dramatically advanced by the development of human 'brain organoids', three-dimensional culture systems that recapitulate selected aspects of human brain development in reductionist, yet complex, tissues in vitro. Here I discuss the promises and challenges this new model system presents.

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Year:  2018        PMID： 29298289     DOI： 10.1038/nmeth.4557

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  25 in total

1.  Cell diversity and network dynamics in photosensitive human brain organoids.

Authors:  Giorgia Quadrato; Tuan Nguyen; Evan Z Macosko; John L Sherwood; Sung Min Yang; Daniel R Berger; Natalie Maria; Jorg Scholvin; Melissa Goldman; Justin P Kinney; Edward S Boyden; Jeff W Lichtman; Ziv M Williams; Steven A McCarroll; Paola Arlotta
Journal:  Nature       Date:  2017-04-26       Impact factor: 49.962

2.  Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration.

Authors:  Yangfei Xiang; Yoshiaki Tanaka; Benjamin Patterson; Young-Jin Kang; Gubbi Govindaiah; Naomi Roselaar; Bilal Cakir; Kun-Yong Kim; Adam P Lombroso; Sung-Min Hwang; Mei Zhong; Edouard G Stanley; Andrew G Elefanty; Janice R Naegele; Sang-Hun Lee; Sherman M Weissman; In-Hyun Park
Journal:  Cell Stem Cell       Date:  2017-07-27       Impact factor: 24.633

Review 3.  Genome-scale neurogenetics: methodology and meaning.

Authors:  Steven A McCarroll; Guoping Feng; Steven E Hyman
Journal:  Nat Neurosci       Date:  2014-05-27       Impact factor: 24.884

Review 4.  The use of brain organoids to investigate neural development and disease.

Authors:  Elizabeth Di Lullo; Arnold R Kriegstein
Journal:  Nat Rev Neurosci       Date:  2017-09-07       Impact factor: 34.870

5.  CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit.

Authors:  Chun-Ting Lee; Jia Chen; Abigail A Kindberg; Raphael M Bendriem; Charles E Spivak; Melanie P Williams; Christopher T Richie; Annelie Handreck; Barbara S Mallon; Carl R Lupica; Da-Ting Lin; Brandon K Harvey; Deborah C Mash; William J Freed
Journal:  Neuropsychopharmacology       Date:  2016-08-18       Impact factor: 7.853

Review 6.  Engineering Stem Cell Organoids.

Authors:  Xiaolei Yin; Benjamin E Mead; Helia Safaee; Robert Langer; Jeffrey M Karp; Oren Levy
Journal:  Cell Stem Cell       Date:  2016-01-07       Impact factor: 24.633

7.  Whole-organism lineage tracing by combinatorial and cumulative genome editing.

Authors:  Aaron McKenna; Gregory M Findlay; James A Gagnon; Marshall S Horwitz; Alexander F Schier; Jay Shendure
Journal:  Science       Date:  2016-05-26       Impact factor: 47.728

8.  Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex.

Authors:  Lei Wang; Shirui Hou; Young-Goo Han
Journal:  Nat Neurosci       Date:  2016-05-23       Impact factor: 24.884

9.  Induction of Expansion and Folding in Human Cerebral Organoids.

Authors:  Yun Li; Julien Muffat; Attya Omer; Irene Bosch; Madeline A Lancaster; Mriganka Sur; Lee Gehrke; Juergen A Knoblich; Rudolf Jaenisch
Journal:  Cell Stem Cell       Date:  2016-12-29       Impact factor: 24.633

10.  Assembly of functionally integrated human forebrain spheroids.

Authors:  Fikri Birey; Jimena Andersen; Christopher D Makinson; Saiful Islam; Wu Wei; Nina Huber; H Christina Fan; Kimberly R Cordes Metzler; Georgia Panagiotakos; Nicholas Thom; Nancy A O'Rourke; Lars M Steinmetz; Jonathan A Bernstein; Joachim Hallmayer; John R Huguenard; Sergiu P Paşca
Journal:  Nature       Date:  2017-04-26       Impact factor: 49.962
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  15 in total

Review 1.  Applications of Human Brain Organoids to Clinical Problems.

Authors:  H Isaac Chen; Hongjun Song; Guo-Li Ming
Journal:  Dev Dyn       Date:  2018-10-02       Impact factor: 3.780

2.  High-Definition Single-Cell Printing: Cell-by-Cell Fabrication of Biological Structures.

Authors:  Pengfei Zhang; Adam R Abate
Journal:  Adv Mater       Date:  2020-11-18       Impact factor: 30.849

3.  Humanized cerebral organoids-based ischemic stroke model for discovering of potential anti-stroke agents.

Authors:  Shu-Na Wang; Zhi Wang; Xi-Yuan Wang; Xiu-Ping Zhang; Tian-Ying Xu; Chao-Yu Miao
Journal:  Acta Pharmacol Sin       Date:  2022-09-13       Impact factor: 7.169

4.  The ethics of experimenting with human brain tissue.

Authors:  Nita A Farahany; Henry T Greely; Steven Hyman; Christof Koch; Christine Grady; Sergiu P Pașca; Nenad Sestan; Paola Arlotta; James L Bernat; Jonathan Ting; Jeantine E Lunshof; Eswar P R Iyer; Insoo Hyun; Beatrice H Capestany; George M Church; Hao Huang; Hongjun Song
Journal:  Nature       Date:  2018-04       Impact factor: 49.962

Review 5.  Development of the Thalamocortical Interactions: Past, Present and Future.

Authors:  Guillermina López-Bendito
Journal:  Neuroscience       Date:  2018-06-20       Impact factor: 3.590

Review 6.  Somatic mutations in neurons during aging and neurodegeneration.

Authors:  Bert M Verheijen; Marc Vermulst; Fred W van Leeuwen
Journal:  Acta Neuropathol       Date:  2018-04-28       Impact factor: 17.088

Review 7.  Negative Symptoms of Schizophrenia and Dopaminergic Transmission: Translational Models and Perspectives Opened by iPSC Techniques.

Authors:  Ginetta Collo; Armida Mucci; Giulia M Giordano; Emilio Merlo Pich; Silvana Galderisi
Journal:  Front Neurosci       Date:  2020-06-18       Impact factor: 4.677

Review 8.  Childhood-Onset Schizophrenia: Insights from Induced Pluripotent Stem Cells.

Authors:  Anke Hoffmann; Michael Ziller; Dietmar Spengler
Journal:  Int J Mol Sci       Date:  2018-11-30       Impact factor: 5.923

9.  Cerebral organoids transplantation improves neurological motor function in rat brain injury.

Authors:  Zhi Wang; Shu-Na Wang; Tian-Ying Xu; Chen Hong; Ming-He Cheng; Peng-Xi Zhu; Jian-Sheng Lin; Ding-Feng Su; Chao-Yu Miao
Journal:  CNS Neurosci Ther       Date:  2020-02-22       Impact factor: 5.243

10.  Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism.

Authors:  Wendy Wenderski; Lu Wang; Andrey Krokhotin; Jessica J Walsh; Hongjie Li; Hirotaka Shoji; Shereen Ghosh; Renee D George; Erik L Miller; Laura Elias; Mark A Gillespie; Esther Y Son; Brett T Staahl; Seung Tae Baek; Valentina Stanley; Cynthia Moncada; Zohar Shipony; Sara B Linker; Maria C N Marchetto; Fred H Gage; Dillon Chen; Tipu Sultan; Maha S Zaki; Jeffrey A Ranish; Tsuyoshi Miyakawa; Liqun Luo; Robert C Malenka; Gerald R Crabtree; Joseph G Gleeson
Journal:  Proc Natl Acad Sci U S A       Date:  2020-04-20       Impact factor: 12.779
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