Literature DB >> 26748754

Engineering Stem Cell Organoids.

Xiaolei Yin1, Benjamin E Mead1, Helia Safaee2, Robert Langer3, Jeffrey M Karp4, Oren Levy5.   

Abstract

Organoid systems leverage the self-organizing properties of stem cells to create diverse multi-cellular tissue proxies. Most organoid models only represent single or partial components of a tissue, and it is often difficult to control the cell type, organization, and cell-cell/cell-matrix interactions within these systems. Herein, we discuss basic approaches to generate stem cell-based organoids, their advantages and limitations, and how bioengineering strategies can be used to steer the cell composition and their 3D organization within organoids to further enhance their utility in research and therapies.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 26748754      PMCID： PMC4728053          DOI： 10.1016/j.stem.2015.12.005

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  82 in total

1.  Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

Authors:  S H Lee; N Lumelsky; L Studer; J M Auerbach; R D McKay
Journal:  Nat Biotechnol       Date:  2000-06       Impact factor: 54.908

2.  Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.

Authors:  Shiro Yui; Tetsuya Nakamura; Toshiro Sato; Yasuhiro Nemoto; Tomohiro Mizutani; Xiu Zheng; Shizuko Ichinose; Takashi Nagaishi; Ryuichi Okamoto; Kiichiro Tsuchiya; Hans Clevers; Mamoru Watanabe
Journal:  Nat Med       Date:  2012-03-11       Impact factor: 53.440

3.  Directed differentiation of embryonic stem cells into motor neurons.

Authors:  Hynek Wichterle; Ivo Lieberam; Jeffery A Porter; Thomas M Jessell
Journal:  Cell       Date:  2002-08-09       Impact factor: 41.582

4.  Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney.

Authors:  M Takasato; P X Er; M Becroft; J M Vanslambrouck; E G Stanley; A G Elefanty; M H Little
Journal:  Nat Cell Biol       Date:  2013-12-15       Impact factor: 28.824

5.  A synthetic genetic edge detection program.

Authors:  Jeffrey J Tabor; Howard M Salis; Zachary Booth Simpson; Aaron A Chevalier; Anselm Levskaya; Edward M Marcotte; Christopher A Voigt; Andrew D Ellington
Journal:  Cell       Date:  2009-06-26       Impact factor: 41.582

6.  3D bioprinting of tissues and organs.

Authors:  Sean V Murphy; Anthony Atala
Journal:  Nat Biotechnol       Date:  2014-08       Impact factor: 54.908

7.  Specification of motoneurons from human embryonic stem cells.

Authors:  Xue-Jun Li; Zhong-Wei Du; Ewa D Zarnowska; Matthew Pankratz; Lauren O Hansen; Robert A Pearce; Su-Chun Zhang
Journal:  Nat Biotechnol       Date:  2005-01-30       Impact factor: 54.908

8.  Identification of stem cells in small intestine and colon by marker gene Lgr5.

Authors:  Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2007-10-14       Impact factor: 49.962

9.  Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.

Authors:  Jason R Spence; Christopher N Mayhew; Scott A Rankin; Matthew F Kuhar; Jefferson E Vallance; Kathryn Tolle; Elizabeth E Hoskins; Vladimir V Kalinichenko; Susanne I Wells; Aaron M Zorn; Noah F Shroyer; James M Wells
Journal:  Nature       Date:  2010-12-12       Impact factor: 49.962

10.  Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures.

Authors:  David A Fluri; Peter D Tonge; Hannah Song; Ricardo P Baptista; Nika Shakiba; Shreya Shukla; Geoffrey Clarke; Andras Nagy; Peter W Zandstra
Journal:  Nat Methods       Date:  2012-03-25       Impact factor: 28.547
View more
  219 in total

Review 1.  Human Colon Organoids and Other Laboratory Strategies to Enhance Patient Treatment Selection.

Authors:  Katherine A Johnson; Rebecca A DeStefanis; Philip B Emmerich; Patrick T Grogan; Jeremy D Kratz; Sarbjeet K Makkar; Linda Clipson; Dustin A Deming
Journal:  Curr Treat Options Oncol       Date:  2020-04-23

Review 2.  Manufacturing Cell Therapies Using Engineered Biomaterials.

Authors:  Amr A Abdeen; Krishanu Saha
Journal:  Trends Biotechnol       Date:  2017-07-12       Impact factor: 19.536

Review 3.  Type III Interferons in Antiviral Defenses at Barrier Surfaces.

Authors:  Alexandra I Wells; Carolyn B Coyne
Journal:  Trends Immunol       Date:  2018-09-12       Impact factor: 16.687

4.  Long-term flow through human intestinal organoids with the gut organoid flow chip (GOFlowChip).

Authors:  Barkan Sidar; Brittany R Jenkins; Sha Huang; Jason R Spence; Seth T Walk; James N Wilking
Journal:  Lab Chip       Date:  2019-10-09       Impact factor: 6.799

5.  An in vivo model of functional and vascularized human brain organoids.

Authors:  Abed AlFatah Mansour; J Tiago Gonçalves; Cooper W Bloyd; Hao Li; Sarah Fernandes; Daphne Quang; Stephen Johnston; Sarah L Parylak; Xin Jin; Fred H Gage
Journal:  Nat Biotechnol       Date:  2018-04-16       Impact factor: 54.908

6.  Engineering multicellular systems: using synthetic biology to control tissue self-organization.

Authors:  Marion B Johnson; Alexander R March; Leonardo Morsut
Journal:  Curr Opin Biomed Eng       Date:  2017-12

7.  Wnt/Yes-Associated Protein Interactions During Neural Tissue Patterning of Human Induced Pluripotent Stem Cells.

Authors:  Julie Bejoy; Liqing Song; Yi Zhou; Yan Li
Journal:  Tissue Eng Part A       Date:  2017-08-31       Impact factor: 3.845

Review 8.  Biomaterials and Culture Systems for Development of Organoid and Organ-on-a-Chip Models.

Authors:  Katya D'Costa; Milena Kosic; Angus Lam; Azeen Moradipour; Yimu Zhao; Milica Radisic
Journal:  Ann Biomed Eng       Date:  2020-04-13       Impact factor: 3.934

9.  Guided self-organization and cortical plate formation in human brain organoids.

Authors:  Madeline A Lancaster; Nina S Corsini; Simone Wolfinger; E Hilary Gustafson; Alex W Phillips; Thomas R Burkard; Tomoki Otani; Frederick J Livesey; Juergen A Knoblich
Journal:  Nat Biotechnol       Date:  2017-05-31       Impact factor: 54.908

10.  Microphysiological Systems: Design, Fabrication, and Applications.

Authors:  Kai Wang; Kun Man; Jiafeng Liu; Yang Liu; Qi Chen; Yong Zhou; Yong Yang
Journal:  ACS Biomater Sci Eng       Date:  2020-05-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.