Literature DB >> 29220651

Replication Fork Reversal: Players and Guardians.

Annabel Quinet1, Delphine Lemaçon1, Alessandro Vindigni2.   

Abstract

Replication fork reversal is a rapidly emerging and remarkably frequent mechanism of fork stabilization in response to genotoxic insults. Here, we summarize recent findings that uncover key molecular determinants for reversed fork formation and describe how the homologous recombination factors BRCA1, BRCA2, and RAD51 protect these structures from extended nucleolytic degradation.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  BRCA1; BRCA2; DNA repair; DNA replication; fork regression; genome instability; homologous recombination; replication fork restart; replication fork reversal; replication stress

Mesh：

Substances：

Year:  2017        PMID： 29220651      PMCID： PMC5895179          DOI： 10.1016/j.molcel.2017.11.022

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  29 in total

1.  Replication stress activates DNA repair synthesis in mitosis.

Authors:  Sheroy Minocherhomji; Songmin Ying; Victoria A Bjerregaard; Sara Bursomanno; Aiste Aleliunaite; Wei Wu; Hocine W Mankouri; Huahao Shen; Ying Liu; Ian D Hickson
Journal:  Nature       Date:  2015-12-02       Impact factor: 49.962

2.  Remodeling of DNA replication structures by the branch point translocase FANCM.

Authors:  Kerstin Gari; Chantal Décaillet; Mathieu Delannoy; Leonard Wu; Angelos Constantinou
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-08       Impact factor: 11.205

3.  Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

Authors:  Katharina Schlacher; Nicole Christ; Nicolas Siaud; Akinori Egashira; Hong Wu; Maria Jasin
Journal:  Cell       Date:  2011-05-13       Impact factor: 41.582

4.  Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage Tolerance.

Authors:  Asami Hishiki; Kodai Hara; Yuzu Ikegaya; Hideshi Yokoyama; Toshiyuki Shimizu; Mamoru Sato; Hiroshi Hashimoto
Journal:  J Biol Chem       Date:  2015-04-09       Impact factor: 5.157

5.  Substrate-selective repair and restart of replication forks by DNA translocases.

Authors:  Rémy Bétous; Frank B Couch; Aaron C Mason; Brandt F Eichman; Maria Manosas; David Cortez
Journal:  Cell Rep       Date:  2013-06-06       Impact factor: 9.423

6.  Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection.

Authors:  Karina Zadorozhny; Vincenzo Sannino; Ondrej Beláň; Jarmila Mlčoušková; Mário Špírek; Vincenzo Costanzo; Lumír Krejčí
Journal:  Cell Rep       Date:  2017-10-10       Impact factor: 9.423

7.  Cooperation of RAD51 and RAD54 in regression of a model replication fork.

Authors:  Dmitry V Bugreev; Matthew J Rossi; Alexander V Mazin
Journal:  Nucleic Acids Res       Date:  2010-11-21       Impact factor: 16.971

8.  Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination.

Authors:  Martin R G Taylor; Mário Špírek; Kathy R Chaurasiya; Jordan D Ward; Raffaella Carzaniga; Xiong Yu; Edward H Egelman; Lucy M Collinson; David Rueda; Lumir Krejci; Simon J Boulton
Journal:  Cell       Date:  2015-07-16       Impact factor: 41.582

9.  Replication fork reversal triggers fork degradation in BRCA2-defective cells.

Authors:  Sofija Mijic; Ralph Zellweger; Nagaraja Chappidi; Matteo Berti; Kurt Jacobs; Karun Mutreja; Sebastian Ursich; Arnab Ray Chaudhuri; Andre Nussenzweig; Pavel Janscak; Massimo Lopes
Journal:  Nat Commun       Date:  2017-10-16       Impact factor: 14.919

10.  Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

Authors:  Angelo Taglialatela; Silvia Alvarez; Giuseppe Leuzzi; Vincenzo Sannino; Lepakshi Ranjha; Jen-Wei Huang; Chioma Madubata; Roopesh Anand; Brynn Levy; Raul Rabadan; Petr Cejka; Vincenzo Costanzo; Alberto Ciccia
Journal:  Mol Cell       Date:  2017-10-19       Impact factor: 17.970
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  97 in total

Review 1.  A tough row to hoe: when replication forks encounter DNA damage.

Authors:  Darshil R Patel; Robert S Weiss
Journal:  Biochem Soc Trans       Date:  2018-12-04       Impact factor: 5.407

2.  Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse.

Authors:  Amaia Ercilla; Sonia Feu; Sergi Aranda; Alba Llopis; Sólveig Hlín Brynjólfsdóttir; Claus Storgaard Sørensen; Luis Ignacio Toledo; Neus Agell
Journal:  Cell Mol Life Sci       Date:  2019-07-11       Impact factor: 9.261

3.  Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase.

Authors:  Steffi Herold; Jacqueline Kalb; Gabriele Büchel; Carsten P Ade; Apoorva Baluapuri; Jiajia Xu; Jan Koster; Daniel Solvie; Anne Carstensen; Christina Klotz; Sabrina Rodewald; Christina Schülein-Völk; Matthias Dobbelstein; Elmar Wolf; Jan Molenaar; Rogier Versteeg; Susanne Walz; Martin Eilers
Journal:  Nature       Date:  2019-03-20       Impact factor: 49.962

4.  CARM1 regulates replication fork speed and stress response by stimulating PARP1.

Authors:  Marie-Michelle Genois; Jean-Philippe Gagné; Takaaki Yasuhara; Jessica Jackson; Sneha Saxena; Marie-France Langelier; Ivan Ahel; Mark T Bedford; John M Pascal; Alessandro Vindigni; Guy G Poirier; Lee Zou
Journal:  Mol Cell       Date:  2021-01-06       Impact factor: 17.970

5.  Loss of Cohesin Subunit Rec8 Switches Rad51 Mediator Dependence in Resistance to Formaldehyde Toxicity in Ustilago maydis.

Authors:  Jeanette H Sutherland; William K Holloman
Journal:  Genetics       Date:  2018-08-06       Impact factor: 4.562

6.  SUMOylation mediates CtIP's functions in DNA end resection and replication fork protection.

Authors:  Andrew J Locke; Lazina Hossain; Glynnis McCrostie; Daryl A Ronato; Amira Fitieh; Tanzeem Ahmed Rafique; Fatemeh Mashayekhi; Mobina Motamedi; Jean-Yves Masson; Ismail Hassan Ismail
Journal:  Nucleic Acids Res       Date:  2021-01-25       Impact factor: 16.971

Review 7.  Restored replication fork stabilization, a mechanism of PARP inhibitor resistance, can be overcome by cell cycle checkpoint inhibition.

Authors:  Brittany Haynes; Junko Murai; Jung-Min Lee
Journal:  Cancer Treat Rev       Date:  2018-09-11       Impact factor: 12.111

8.  SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.

Authors:  Yusuke Okamoto; Masako Abe; Anfeng Mu; Yasuko Tempaku; Colette B Rogers; Ayako L Mochizuki; Yoko Katsuki; Masato T Kanemaki; Akifumi Takaori-Kondo; Alexandra Sobeck; Anja-Katrin Bielinsky; Minoru Takata
Journal:  Blood       Date:  2021-01-21       Impact factor: 22.113

Review 9.  Impact of Replication Stress in Human Papillomavirus Pathogenesis.

Authors:  Cary A Moody
Journal:  J Virol       Date:  2019-01-04       Impact factor: 5.103

Review 10.  BRCA1 Mutations in Cancer: Coordinating Deficiencies in Homologous Recombination with Tumorigenesis.

Authors:  John J Krais; Neil Johnson
Journal:  Cancer Res       Date:  2020-08-03       Impact factor: 12.701
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