Ali Nozari1, Shabnam Ajami2, Azade Rafiei3, Elmira Niazi4. 1. Assistant Professor, Department of Paediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Fars, Iran. 2. Assistant Professor, Department of Orthodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Fars, Iran. 3. Assistant Professor, Oral and Dental Disease Research Center, Department of Paediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. 4. Postgraduate Student, Oral and Dental Disease Research Center, Department of Paediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract
INTRODUCTION: Dental caries is still prevailing worldwide, although different anti caries products have been introduced. Each remineralizing agent has its own shortcomings. Therefore, looking for new agents to have benefits of previous ones with lesser side effects is worthwhile. AIM: To determine the remineralization ability of NaF varnish, nano-Hydroxyapatite Serum (n-HAP) and Nano Silver Fluoride (NSF) on enamel of primary anterior teeth. MATERIALS AND METHODS: Incipient caries were induced in primary sound anterior teeth by storing each specimen in demineralization solution for 72 hours. Then they were randomly divided into four groups of 15 samples each: (1) NaF varnish; (2) n-HAP repairing serum; (3) NSF and (4) no treatment (control). Surface Microhardness (SMH) was assessed with Vickers micro hardness tester before and after demineralization and after 10 days of pH-cycling. A total of 12 random specimens from groups 1 to 4 (3 random samples of each group) were examined by Atomic Force Microscopy (AFM). The SMH values were analysed with one-way and repeated measures ANOVA. Level of significance was set at p=0.05. RESULTS: Post lesion SMH values significantly decreased in all groups (p<0.001). Post treatment SMH values significantly increased in comparison to post lesion ones (p<0.001) except for control group which was not different statistically (p=0.86). The highest SMH values were observed in NSF group (mean 222.90 ± 28.79). Statistically significant differences were shown between all groups (p<0.05). However, NaF varnish and n-HAP groups were not statistically different (p=0.165). AFM images demonstrated protective layers in all treated groups. CONCLUSION: The results of this in vitro study suggest that NSF could have the greatest remineralization efficacy. NaF varnish and n-HAP serum were similar in remineralizing initial caries. Future clinical studies are recommended for selection of the most appropriate remineralizing agent in primary teeth.
INTRODUCTION: Dental caries is still prevailing worldwide, although different anti caries products have been introduced. Each remineralizing agent has its own shortcomings. Therefore, looking for new agents to have benefits of previous ones with lesser side effects is worthwhile. AIM: To determine the remineralization ability of NaF varnish, nano-Hydroxyapatite Serum (n-HAP) and Nano Silver Fluoride (NSF) on enamel of primary anterior teeth. MATERIALS AND METHODS: Incipient caries were induced in primary sound anterior teeth by storing each specimen in demineralization solution for 72 hours. Then they were randomly divided into four groups of 15 samples each: (1) NaF varnish; (2) n-HAP repairing serum; (3) NSF and (4) no treatment (control). Surface Microhardness (SMH) was assessed with Vickers micro hardness tester before and after demineralization and after 10 days of pH-cycling. A total of 12 random specimens from groups 1 to 4 (3 random samples of each group) were examined by Atomic Force Microscopy (AFM). The SMH values were analysed with one-way and repeated measures ANOVA. Level of significance was set at p=0.05. RESULTS: Post lesion SMH values significantly decreased in all groups (p<0.001). Post treatment SMH values significantly increased in comparison to post lesion ones (p<0.001) except for control group which was not different statistically (p=0.86). The highest SMH values were observed in NSF group (mean 222.90 ± 28.79). Statistically significant differences were shown between all groups (p<0.05). However, NaF varnish and n-HAP groups were not statistically different (p=0.165). AFM images demonstrated protective layers in all treated groups. CONCLUSION: The results of this in vitro study suggest that NSF could have the greatest remineralization efficacy. NaF varnish and n-HAP serum were similar in remineralizing initial caries. Future clinical studies are recommended for selection of the most appropriate remineralizing agent in primary teeth.
Authors: Fabíola Galbiatti de Carvalho; Basílio Rodrigues Vieira; Rogério Lacerda Dos Santos; Hugo Lemes Carlo; Pablo Queiroz Lopes; Bruno Alessandro Silva Guedes de Lima Journal: Pediatr Dent Date: 2014 May-Jun Impact factor: 1.874
Authors: Dina I El-Desouky; Azza Hanno; Yasmine Elhamouly; Sara A Hamza; Lubna M El-Desouky; Karin M L Dowidar Journal: BMC Oral Health Date: 2022-06-20 Impact factor: 3.747
Authors: C Pushpalatha; K V Bharkhavy; Arshiya Shakir; Dominic Augustine; S V Sowmya; Hammam Ahmed Bahammam; Sarah Ahmed Bahammam; Nassreen Hassan Mohammad Albar; Bassam Zidane; Shankargouda Patil Journal: Front Bioeng Biotechnol Date: 2022-07-01