| Literature DB >> 29207473 |
Boshen Jiao1, Zafar Zafari2, Brian Will3, Kai Ruggeri4, Shukai Li5, Peter Muennig6.
Abstract
Aircraft noise increases the risk of cardiovascular diseases and mental illness. The allowable limit for sound in the vicinity of an airport is 65 decibels (dB) averaged over a 24-h 'day and night' period (DNL) in the United States. We evaluate the trade-off between the cost and the health benefits of changing the regulatory DNL level from 65 dB to 55 dB using a Markov model. The study used LaGuardia Airport (LGA) as a case study. In compliance with 55 dB allowable limit of aircraft noise, sound insulation would be required for residential homes within the 55 dB to 65 dB DNL. A Markov model was built to assess the cost-effectiveness of installing sound insulation. One-way sensitivity analyses and Monte Carlo simulation were conducted to test uncertainty of the model. The incremental cost-effectiveness ratio of installing sound insulation for residents exposed to airplane noise from LGA was $11,163/QALY gained (95% credible interval: cost-saving and life-saving to $93,054/QALY gained). Changing the regulatory standard for noise exposure around airports from 65 dB to 55 dB comes at a very good value.Entities:
Keywords: aircraft noise; cost-effectiveness; regulatory change; sound insulation
Mesh:
Year: 2017 PMID: 29207473 PMCID: PMC5750915 DOI: 10.3390/ijerph14121497
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Figure 1Noise levels around La Guardia Airport. Source: MSP FairSkies Coalition and University of Minnesota Center for Urban and Regional Affairs, 2010 [23].
Values used in the Markov model evaluating changing the regulatory day–night average sound level (DNL) from 65 decibels (dB) to 55 dB versus the status quo.
| Parameter | Base | Standard Error/Range | Distribution * | Source |
|---|---|---|---|---|
| Direct Cost | ||||
| Medical cost of cardiovascular disease (CVD) | 23,229 | 5807 | Gamma | Nichols et al., 2010 |
| Medical cost of anxiety | 2814 | 704 | Gamma | Greenberg et al., 1999 |
| Cost of sound insulation | 18,959 | 4740 | Gamma | Wolfe et al., 2016 |
| Indirect Cost | ||||
| Productivity loss of CVD | 12,837 | 3209 | Gamma | Lloyd-Jones et al., 2010; Nichols et al., 2010 |
| Productivity loss of Anxiety | 313 | 78 | Gamma | Greenberg et al., 1999 |
| Health utility decrement due to CVD | 0.283 | 0.0130 | Beta | Ara et al., 2010; Ara et al., 2009 |
| Health utility decrement due to anxiety | 0.156 | 0.0391 | Beta | EQ5D |
| Health utility of CVD history | 0.844 | 0.0096 | Beta | Ara et al., 2010; Ara et al., 2009 |
| Probability of developing a CVD (by age) | Mozaffarian et al., 2016 | |||
| 35–44 | 0.15% | 0.04% | Beta | |
| 45–54 | 0.71% | 0.18% | Beta | |
| 55–64 | 1.49% | 0.37% | Beta | |
| 65–74 | 2.66% | 0.67% | Beta | |
| 75–84 | 4.78% | 1.20% | Beta | |
| 85 and above | 6.81% | 1.70% | Beta | |
| Probability of developing an anxiety disorder | 18.10% | 0.70% | Beta | Kessler et al., 2005 |
| RR of CVD for aircraft noise exposure | 1.12 | low: 1.07; high: 1.18 | Triangular | Hansell et al., 2013 |
| RR of anxiety for aircraft noise exposure | 1.69 | low: 1.00; high: 2.66 | Triangular | Hardoy et al., 2005 |
| RR of anxiety for CVD patients | 1.66 | low: 1.49; high: 1.82 | Triangular | Fan et al., 2008 |
| RR of CVD among those with prior CVD history | 1.97 | low: 1.67; high: 2.30 | Triangular | Nichols et al., 2010 |
* For use in the Monte Carlo simulation.
Figure 2Markov model diagram.
Costs (2016 U.S.$), incremental cost, quality-adjusted life years (QALYs) gained, incremental QALYs gained, and incremental cost-effectiveness (ICER) of changing the regulatory day–night average sound level (DNL) from 65 decibels (dB) to 55 dB versus the status quo.
| Strategy | Cost | Incremental Cost | QALY | Incremental QALY | ICER * |
|---|---|---|---|---|---|
| Status quo | 635,369 | 19.61 | |||
| Changing the regulatory DNL level from 65 dB to 55 dB | 642,162 | 6793 | 20.22 | 0.61 | 11,163 |
* Incremental cost-effectiveness ratio was determined by cost (2016 U.S.$) per quality-adjusted life years (QALY) gained.
One-way sensitivity analyses of the cost-effectiveness of changing the regulatory day–night average sound level (DNL) from 65 decibels (dB) to 55 dB versus the status quo.
| Variable | Incremental Cost-Effectiveness Ratio * | |
|---|---|---|
| Low | High | |
| Relative risk (RR) of anxiety for aircraft noise exposure (Low: 1.00; High: 2.66) | 195,717 | Cost-saving |
| Cost of sound insulation (Low: −25%; High: +25%) † | Cost-saving | 24,448 |
| RR of cardiovascular disease (CVD) for aircraft noise exposure (Low: 1.07; High: 1.18) | 20,539 | 2822 |
| Medical cost of anxiety (Low: −25%; High: +25%) † | 16,316 | 6010 |
| Medical cost of CVD (Low: −25%; High: +25%) † | 15,931 | 6394 |
| Probability of developing a CVD (Low: −25%; High: +25%) | 13,830 | 7064 |
| RR of anxiety for CVD patients (Low: 1.49; High: 1.82) | 13,838 | 8912 |
| Health utility decrement due to anxiety (Low: 0.117; High: 0.195) | 13,914 | 9320 |
| Productivity loss of CVD (Low: −25%; High: +25%) † | 12,860 | 9466 |
* Incremental cost-effectiveness ratio was determined by cost (2016 U.S.$) per quality-adjusted life years (QALY) gained; † We used ±25% for estimates with no random error, but that likely have geographic variation in costs. These high and low values roughly reflect the variation in the cost of living across localities in the United States.
Figure 3Incremental cost-effectiveness scatter-plot, changing the regulatory DNL level from 65 dB to 55 dB versus the status quo.