| Literature DB >> 30111739 |
Zafar Zafari1,2, Boshen Jiao3, Brian Will4, Shukai Li5, Peter Alexander Muennig6.
Abstract
Objectives: Airports in the U.S. have gradually been transitioning to automated flight systems. These systems generate new flight paths over populated areas. While they can improve flight efficiency, the increased noise associated with these novel flight patterns potentially pose serious health threats to the overflown communities. In this case study, we estimated the monetary benefits relative to health losses associated with one significant change in flight patterns at LaGuardia Airport, year-round use of "TNNIS Climb", which happened in 2012 as a result of flight automation in New York City. Prior to that, the use of the TNNIS Climb was limited to the U.S. Open tennis matches.Entities:
Keywords: Markov model; aircraft noise; cardiovascular disease; cost-effectiveness
Mesh:
Year: 2018 PMID: 30111739 PMCID: PMC6121545 DOI: 10.3390/ijerph15081753
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Parameters used for the Markov model to evaluate the cost-effectiveness of the limited vs. the year-round use of TNNIS Climb at La Guardia Airport in New York City.
| Parameters | Mean (Standard Error/Range) | Distribution | References |
|---|---|---|---|
|
| |||
| Population of Queens affected by TNNIS noise | 83,807 | - | [ |
| Background mortality rates | U.S. Life Tables | [ | |
| Risk of developing a CVD event (by age) | [ | ||
| 35–44 | 0.0015 (0.0004) | Beta | |
| 45–54 | 0.0071 (0.0018) | Beta | |
| 55–64 | 0.0149 (0.0037) | Beta | |
| 65–74 | 0.0266 (0.0067) | Beta | |
| 75–84 | 0.0478 (0.0120) | Beta | |
| 85+ | 0.0681 (0.0170) | Beta | |
| Relative risk of CVD among those with prior history of CVD | 1.965 (1.67–2.30) | Log-normal | [ |
| Risk of an anxiety disorder | 0.18 (0.0070) | Beta | [ |
| Relative risk of anxiety for CVD patients | 1.66 (1.49–1.82) | Log-normal | [ |
| Relative risk of CVD for aircraft noise exposure | 1.14 (1.08–1.20) | Log-normal | [ |
| Relative risk of anxiety for aircraft noise exposure | 1.79 (1.00–3.06) | Log-normal | [ |
|
| |||
| Direct medical costs of CVD | 23,229 (5807) | Gamma | [ |
| Direct medical costs of anxiety | 2814 (704) | Gamma | [ |
| Indirect medical costs of CVD | 12,837 (3209) | Gamma | [ |
| Indirect medical costs of anxiety | 313 (78) | Gamma | [ |
| Total incremental operating costs (limited vs. year-round use of TNNIS) | 127,040,655 (31,760,164) | Author estimation | |
| Incremental operating costs per person exposed to noise (limited vs. year-round use of TNNIS) (Total divided by 83,807) | 1516 (379) | Gamma | |
| Total incremental productivity loss (limited vs. year-round use of TNNIS) | $19,956,042 ($4,989,010) | Author estimation | |
| Incremental productivity loss per person exposed to noise (limited vs. year-round use of TNNIS) (Total divided by 83,807) | 238 (59) | Gamma | |
|
| |||
| Disutility associated with a CVD event | 0.283 (0.0130) | Beta | [ |
| Disutility associated with anxiety | 0.16 (0.04 *) | Beta | [ |
| Utility of prior history of CVD event health state | 0.844 (0.0096) | Beta | [ |
All costs are adjusted to 2016 U.S. dollars using U.S. Consumer Price Index [41]. CVD: cardiovascular diseases. * For the standard error we assumed a 25% coefficient of variation.
Expected lifetime costs and QALYs for an average person exposed to noise associated with the limited use as well as the year-round use of the TNNIS Climb at La Guardia Airport (LGA) in New York.
| Scenario | Costs | Incremental Costs | QALYs | Incremental QALYs | ICER ($/QALY) |
|---|---|---|---|---|---|
| Limited use of TNNIS | 656,173 | 11,288 | 18.72 | 1.13 | 10,006 |
| Year-round use of TNNIS | 644,885 | 17.6 | Reference |
QALYs: quality-adjusted life year, ICER: Incremental cost-effectiveness ratio.
Figure 1Cost-effectiveness plane for the limited vs. the year-round use of TNNIS Climb at La Guardia Airport (LGA) in New York City.
Figure 2Cost-effectiveness (CE) acceptability curve for the limited vs. the year-round use of TNNIS Climb at La Guardia Airport (LGA) in New York City.
One-way sensitivity analyses for cost-effectiveness of the limited versus the year-round use of TNNIS Climb at La Guardia Airport (LGA) in New York City.
| Input Parameters | Low | High |
|---|---|---|
| RR of anxiety for aircraft noise exposure (1.00–3.06) | −3574 | 208,108 |
| Probability of anxiety for people without CVD (0.08 to 0.28) | 1694 | 33,826 |
| Incremental operating costs per person exposed to noise (limited vs. year-round use of TNNIS) (1137 to 1895) | 2345 | 17,668 |
| Health utility decrement for anxiety (−0.26 to −0.06) | 6508 | 21,641 |
| RR of CVD for aircraft noise exposure (1.0–1.18) | 5065 | 15,876 |
| Direct costs of anxiety (2111 to 3518) | 6947 | 13,062 |
| Direct costs of CVD (17,422 to 29,036) | 7041 | 12,972 |
| RR of anxiety for CVD patients (1.49–1.82) | 8303 | 12,109 |
| Prevalence of CVD in general population (0.25 to 0.45) | 8431 | 11,566 |
| Age at baseline (31 to 51) | 8625 | 11,655 |
| Incremental productivity loss per person exposed to noise (limited vs. year-round use of TNNIS) (178.5, 297.5) | 8804 | 11,209 |
| Indirect costs of CVD (9628 to 16,046) | 8951 | 11,062 |
| Health utility decrement for CVD (−0.38 to −0.18) | 9374 | 10,771 |
| Health utility of people with a prior history of CVD (0.74 to 0.94) | 9669 | 10,401 |
| Indirect costs of anxiety (235 to 391) | 9668 | 10,346 |
| RR of CVD for people with a prior history of CVD (1.7 to 2.3) | 9764 | 10,238 |
| Discount rate (0.00 to 0.05) | 9978 | 10,365 |
CVD: cardiovascular diseases; RR: relative rate; QALYs: quality-adjusted life year, ICER: Incremental cost-effectiveness ratio.