| Literature DB >> 29097400 |
John J McGrath1, Sukanta Saha2, Carmen C W Lim2, Sergio Aguilar-Gaxiola2, Jordi Alonso2, Laura H Andrade2, Evelyn J Bromet2, Ronny Bruffaerts2, José M Caldas de Almeida2, Graça Cardoso2, Giovanni de Girolamo2, John Fayyad2, Silvia Florescu2, Oye Gureje2, Josep M Haro2, Norito Kawakami2, Karestan C Koenen2, Viviane Kovess-Masfety2, Sing Lee2, Jean-Pierre Lepine2, Katie A McLaughlin2, Maria E Medina-Mora2, Fernando Navarro-Mateu2, Akin Ojagbemi2, Jose Posada-Villa2, Nancy Sampson2, Kate M Scott2, Hisateru Tachimori2, Margreet Ten Have2, Kenneth S Kendler2, Ronald C Kessler2.
Abstract
BackgroundTraumatic events are associated with increased risk of psychotic experiences, but it is unclear whether this association is explained by mental disorders prior to psychotic experience onset.AimsTo investigate the associations between traumatic events and subsequent psychotic experience onset after adjusting for post-traumatic stress disorder and other mental disorders.MethodWe assessed 29 traumatic event types and psychotic experiences from the World Mental Health surveys and examined the associations of traumatic events with subsequent psychotic experience onset with and without adjustments for mental disorders.ResultsRespondents with any traumatic events had three times the odds of other respondents of subsequently developing psychotic experiences (OR = 3.1, 95% CI 2.7-3.7), with variability in strength of association across traumatic event types. These associations persisted after adjustment for mental disorders.ConclusionsExposure to traumatic events predicts subsequent onset of psychotic experiences even after adjusting for comorbid mental disorders. © The Royal College of Psychiatrists 2017.Entities:
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Year: 2017 PMID： 29097400 PMCID： PMC5709675 DOI： 10.1192/bjp.bp.117.205955
Source DB: PubMed Journal: Br J Psychiatry ISSN： 0007-1250 Impact factor: 9.319