Literature DB >> 29068823

Five Dimensions of Research Ethics: A Stakeholder Framework for Creating a Climate of Research Integrity.

James M DuBois1, Alison L Antes.   

Abstract

The authors explore five dimensions of research ethics: (1) normative ethics, which includes meta-ethical questions; (2) compliance with regulations, statutes, and institutional policies; (3) the rigor and reproducibility of science; (4) social value; and (5) workplace relationships. Each of the five dimensions is important not only because it addresses an aspect of good research done in a good manner but also because it addresses the concerns of key stakeholders in the research enterprise. The five-dimension framework can guide institutions as they answer three questions central to any research ethics program: (1) Who should champion research ethics? (2) What should interventions look like? and (3) Who should participate in the interventions? The framework is valuable because the answers to these three questions are radically different depending on the dimension under consideration. An expanded vision of research ethics does not entail that institutions should require additional online training or approvals from institutional review boards. However, without acknowledging all five dimensions, programs risk missing an important aspect of research ethics or ignoring the interests of important stakeholders.

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Mesh:

Year:  2018        PMID: 29068823      PMCID: PMC5916747          DOI: 10.1097/ACM.0000000000001966

Source DB:  PubMed          Journal:  Acad Med        ISSN: 1040-2446            Impact factor:   6.893


  34 in total

1.  What makes clinical research ethical?

Authors:  E J Emanuel; D Wendler; C Grady
Journal:  JAMA       Date:  2000 May 24-31       Impact factor: 56.272

Review 2.  Dissemination of results in community-based participatory research.

Authors:  Peggy G Chen; Nitza Diaz; Georgina Lucas; Marjorie S Rosenthal
Journal:  Am J Prev Med       Date:  2010-10       Impact factor: 5.043

3.  Journals unite for reproducibility.

Authors:  Marcia McNutt
Journal:  Science       Date:  2014-11-07       Impact factor: 47.728

4.  Putting together a scientific team: collaborative science.

Authors:  L Garry Adams
Journal:  Trends Microbiol       Date:  2014-06-02       Impact factor: 17.079

5.  Misconduct: Lessons from researcher rehab.

Authors:  James M DuBois; John T Chibnall; Raymond Tait; Jillon Vander Wal
Journal:  Nature       Date:  2016-06-09       Impact factor: 49.962

6.  Ethics and clinical research.

Authors:  H K Beecher
Journal:  N Engl J Med       Date:  1966-06-16       Impact factor: 91.245

7.  Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report.

Authors:  James M Dubois; Jeffrey M Dueker
Journal:  J Res Adm       Date:  2009

8.  Policy: NIH plans to enhance reproducibility.

Authors:  Francis S Collins; Lawrence A Tabak
Journal:  Nature       Date:  2014-01-30       Impact factor: 49.962

9.  Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles.

Authors:  Jennifer A Hobin; Anne M Deschamps; Richard Bockman; Stanley Cohen; Paul Dechow; Charis Eng; William Galey; Mariana Morris; Sharma Prabhakar; Usha Raj; Peter Rubenstein; John A Smith; Patrick Stover; Nancy Sung; William Talman; Richard Galbraith
Journal:  J Transl Med       Date:  2012-04-13       Impact factor: 5.531

Review 10.  Understanding research misconduct: a comparative analysis of 120 cases of professional wrongdoing.

Authors:  James M DuBois; Emily E Anderson; John Chibnall; Kelly Carroll; Tyler Gibb; Chiji Ogbuka; Timothy Rubbelke
Journal:  Account Res       Date:  2013       Impact factor: 2.622

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  9 in total

1.  Leading for research excellence and integrity: A qualitative investigation of the relationship-building practices of exemplary principal investigators.

Authors:  Alison L Antes; Ashley Kuykendall; James M DuBois
Journal:  Account Res       Date:  2019-05-14       Impact factor: 2.622

2.  Understanding the Use of Optimal Formatting and Plain Language When Presenting Key Information in Clinical Trials.

Authors:  Erin D Solomon; Jessica Mozersky; Matthew P Wroblewski; Kari Baldwin; Meredith V Parsons; Melody Goodman; James M DuBois
Journal:  J Empir Res Hum Res Ethics       Date:  2021-08-19       Impact factor: 1.742

3.  For the "good of the lab": Insights from three focus groups concerning the ethics of managing a laboratory or research group.

Authors:  David B Resnik; Edith Lee; Bill Jirles; Elise Smith; Kathy Barker
Journal:  Account Res       Date:  2021-09-30       Impact factor: 2.622

4.  What Explains Associations of Researchers' Nation of Origin and Scores on a Measure of Professional Decision-Making? Exploring Key Variables and Interpretation of Scores.

Authors:  Alison L Antes; Tammy English; Kari A Baldwin; James M DuBois
Journal:  Sci Eng Ethics       Date:  2019-01-02       Impact factor: 3.525

5.  Assessing the climate for research ethics in labs: Development and validation of a brief measure.

Authors:  Erin D Solomon; Tammy English; Matthew Wroblewski; James M DuBois; Alison L Antes
Journal:  Account Res       Date:  2021-02-04       Impact factor: 2.622

6.  How to Conduct Responsible Research: A Guide for Graduate Students.

Authors:  Alison L Antes; Leonard B Maggi
Journal:  Curr Protoc       Date:  2021-03

7.  The lab management practices of "Research Exemplars" that foster research rigor and regulatory compliance: A qualitative study of successful principal investigators.

Authors:  Alison L Antes; Ashley Kuykendall; James M DuBois
Journal:  PLoS One       Date:  2019-04-24       Impact factor: 3.240

8.  Design, implementation, and evaluation of PINDAR, a novel short program on GCP for academic medical center principal investigators conducting human subject research.

Authors:  Claudia S Plottel; Lois Mannon; Frederick G More; Stuart D Katz; Judith S Hochman
Journal:  J Clin Transl Sci       Date:  2018-12

9.  Perceived barriers to assessing understanding and appreciation of informed consent in clinical trials: A mixed-method study.

Authors:  Erin D Solomon; Jessica Mozersky; Kari Baldwin; Matthew P Wroblewski; Meredith V Parsons; Melody Goodman; James M DuBois
Journal:  J Clin Transl Sci       Date:  2021-06-26
  9 in total

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