Literature DB >> 29045

Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex.

D A Matthews, R A Alden, J T Bolin, D J Filman, S T Freer, R Hamlin, W G Hol, R L Kisliuk, E J Pastore, L T Plante, N Xuong, J Kraut.   

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Year:  1978        PMID： 29045

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  17 in total

1.  Structure of a bacterial enzyme regulated by phosphorylation, isocitrate dehydrogenase.

Authors:  J H Hurley; P E Thorsness; V Ramalingam; N H Helmers; D E Koshland; R M Stroud
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

2.  Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.

Authors:  Thommey P Thomas; Baohua Huang; Seok Ki Choi; Justin E Silpe; Alina Kotlyar; Ankur M Desai; Hong Zong; Jeremy Gam; Melvin Joice; James R Baker
Journal:  Mol Pharm       Date:  2012-08-07       Impact factor: 4.939

3.  Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae.

Authors:  P V Adrian; K P Klugman
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

4.  Flexibases: a way to enhance the use of molecular docking methods.

Authors:  S K Kearsley; D J Underwood; R P Sheridan; M D Miller
Journal:  J Comput Aided Mol Des       Date:  1994-10       Impact factor: 3.686

5.  The nucleotide sequence of the trimethoprim-resistant dihydrofolate reductase gene harbored by Tn7.

Authors:  M E Fling; C Richards
Journal:  Nucleic Acids Res       Date:  1983-08-11       Impact factor: 16.971

6.  Computer simulation of the dynamics of hydrated protein crystals and its comparison with x-ray data.

Authors:  W F van Gunsteren; H J Berendsen; J Hermans; W G Hol; J P Postma
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

7.  Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic.

Authors:  Thommey P Thomas; Melvin Joice; Madhuresh Sumit; Justin E Silpe; Alina Kotlyar; Sophia Bharathi; Jolanta Kukowska-Latallo; James R Baker; Seok Ki Choi
Journal:  Curr Pharm Des       Date:  2013       Impact factor: 3.116

8.  19F-n.m.r. studies of 3',5'-difluoromethotrexate binding to Lactobacillus casei dihydrofolate reductase. Molecular motion and coenzyme-induced conformational changes.

Authors:  G M Clore; A M Gronenborn; B Birdsall; J Feeney; G C Roberts
Journal:  Biochem J       Date:  1984-02-01       Impact factor: 3.857

9.  A 1H n.m.r. study of the role of the glutamate moiety in the binding of methotrexate to Lactobacillus casei dihydrofolate reductase.

Authors:  D J Antonjuk; B Birdsall; H T Cheung; G M Clore; J Feeney; A Gronenborn; G C Roberts; T Q Tran
Journal:  Br J Pharmacol       Date:  1984-02       Impact factor: 8.739

10.  The kinetic mechanism of the major form of ox kidney aldehyde reductase with D-glucuronic acid.

Authors:  A K Daly; T J Mantle
Journal:  Biochem J       Date:  1982-08-01       Impact factor: 3.857
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