Literature DB >> 2900825

Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the rat liver by methylglyoxal.

A Martelli1, M Ghia, E Mereto, U M Marinari, G Brambilla.   

Abstract

The effect of pre-(initiation) and post-(promotion) administration of methylglyoxal (MG) on the induction of gamma-glutamyltranspeptidase (GGT)-positive foci in the liver of F344 male rats was investigated. GGT-positive foci were produced in dose-related amounts by 0.05 and 0.2% MG in drinking water, either when administered to uninitiated rats or when given in the promotion phase.

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Year:  1988        PMID： 2900825      PMCID： PMC5917568          DOI： 10.1111/j.1349-7006.1988.tb02218.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


methylglyoxal γ‐glutamyltranspeptidase 2 ‐ acetylaminofluorene N‐nitrosodiethylamine phenobarbital
  16 in total

1.  Methylglyoxal-induced mutation to 6-thioguanine resistance in V79 cells.

Authors:  E Cajelli; R Canonero; A Martelli; G Brambilla
Journal:  Mutat Res       Date:  1987-01       Impact factor: 2.433

2.  Nonenzymic, polyvalent anion-catalyzed formation of methylglyoxal as an explanation of its presence in physiological systems.

Authors:  V Riddle; F W Lorenz
Journal:  J Biol Chem       Date:  1968-05-25       Impact factor: 5.157

Review 3.  Preneoplastic lesions as end points in carcinogenicity testing. I. Hepatic preneoplasia.

Authors:  P Bannasch
Journal:  Carcinogenesis       Date:  1986-05       Impact factor: 4.944

Review 4.  The sequential analysis of cancer development.

Authors:  E Farber; R Cameron
Journal:  Adv Cancer Res       Date:  1980       Impact factor: 6.242

5.  Mutagens-carcinogens in foods.

Authors:  T Sugimura; S Sato
Journal:  Cancer Res       Date:  1983-05       Impact factor: 12.701

6.  Induction of sister-chromatid exchanges in Chinese hamster ovary cells by the biotic ketoaldehyde methylglyoxal.

Authors:  P Faggin; A M Bassi; R Finollo; G Brambilla
Journal:  Mutat Res       Date:  1985-11       Impact factor: 2.433

7.  The quantitative analysis and stability of histochemical markers of altered hepatic foci in rat liver following initiation by diethylnitrosamine administration and promotion with phenobarbital.

Authors:  T L Goldsworthy; H C Pitot
Journal:  Carcinogenesis       Date:  1985-09       Impact factor: 4.944

8.  Phenotypic diversity as an early property of putative preneoplastic hepatocyte populations in liver carcinogenesis.

Authors:  K Ogawa; D B Solt; E Farber
Journal:  Cancer Res       Date:  1980-03       Impact factor: 12.701

9.  Survey of various chemicals for initiating and promoting activities in a short-term in vivo system based on generation of hyperplastic liver nodules in rats.

Authors:  M Tatematsu; R Hasegawa; K Imaida; H Tsuda; N Ito
Journal:  Carcinogenesis       Date:  1983       Impact factor: 4.944

10.  Induction of ornithine decarboxylase and DNA synthesis in rat stomach mucosa by methylglyoxal.

Authors:  C Furihata; Y Sato; T Matsushima; M Tatematsu
Journal:  Carcinogenesis       Date:  1985-01       Impact factor: 4.944
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