Literature DB >> 3796671

Methylglyoxal-induced mutation to 6-thioguanine resistance in V79 cells.

E Cajelli, R Canonero, A Martelli, G Brambilla.   

Abstract

Methylglyoxal, at concentrations ranging from 0.16 to 1.5 mM, caused a dose-dependent increase in the frequency of HGPRT-deficient mutants in V79 cells. Its mutagenic activity was reduced when V79 cells were co-cultured with freshly isolated rat hepatocytes.

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Year:  1987        PMID： 3796671     DOI： 10.1016/0165-7992(87)90081-9

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  3 in total

1.  Incidence and potential implications of the toxic metabolite methylglyoxal in cell culture: A review.

Authors:  F W Chaplen
Journal:  Cytotechnology       Date:  1998-05       Impact factor: 2.058

Review 2.  Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease.

Authors:  Seigmund Wai Tsuen Lai; Edwin De Jesus Lopez Gonzalez; Tala Zoukari; Priscilla Ki; Sarah C Shuck
Journal:  Chem Res Toxicol       Date:  2022-10-05       Impact factor: 3.973

3.  Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the rat liver by methylglyoxal.

Authors:  A Martelli; M Ghia; E Mereto; U M Marinari; G Brambilla
Journal:  Jpn J Cancer Res       Date:  1988-06
  3 in total

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