Literature DB >> 4058437

Induction of sister-chromatid exchanges in Chinese hamster ovary cells by the biotic ketoaldehyde methylglyoxal.

P Faggin, A M Bassi, R Finollo, G Brambilla.   

Abstract

The number of sister-chromatid exchanges (SCEs) per metaphase was determined in Chinese hamster ovary cells after 16 h exposure to methylglyoxal (MG) concentrations ranging from 0.1 to 0.75 mM. MG produced an increase of SCE frequency that proved to be dose-dependent, and to reach a maximum of 2 X baseline at the highest nontoxic concentration (0.5 mM).

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Year:  1985        PMID: 4058437     DOI: 10.1016/0165-7992(85)90138-1

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  3 in total

Review 1.  The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.

Authors:  P J Thornalley
Journal:  Biochem J       Date:  1990-07-01       Impact factor: 3.857

2.  Passive cigarette smoke and the renal glyoxalase system.

Authors:  Swati Biswas; C Gary Gairola; Salil K Das
Journal:  Mol Cell Biochem       Date:  2002-01       Impact factor: 3.396

3.  Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the rat liver by methylglyoxal.

Authors:  A Martelli; M Ghia; E Mereto; U M Marinari; G Brambilla
Journal:  Jpn J Cancer Res       Date:  1988-06
  3 in total

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