Literature DB >> 2883894

Polynesian origins and affinities: globin gene variants in eastern Polynesia.

A V Hill, B Gentile, J M Bonnardot, J Roux, D J Weatherall, J B Clegg.   

Abstract

Analysis of copy number variants of the duplicated alpha-, zeta-, and gamma-globin genes in eastern Polynesians revealed a high frequency of both triplicated-zeta-gene chromosomes and a specific alpha thalassemia deletion. This deletion and a novel restriction-enzyme-site polymorphism associated with a zeta zeta zeta chromosome are found only in Melanesians and Polynesians. Analysis of alpha-globin restriction-enzyme haplotypes indicated further similarities to Melanesians but suggested an additional non-Melanesian genetic component in eastern Polynesia. Several globin gene alleles showed evidence of marked frequency fluctuations due to genetic drift.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 2883894      PMCID： PMC1684144     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  18 in total

1.  Alpha globin gene rearrangements in Polynesians are not associated with malaria.

Authors:  R J Trent; K N Mickleson; T Wilkinson; J Yakas; R Bluck; M Dixon; A W Liley; H Kronenberg
Journal:  Am J Hematol       Date:  1985-04       Impact factor: 10.047

2.  Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.

Authors:  D R Higgs; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

Review 3.  DNA polymorphism and molecular pathology of the human globin gene clusters.

Authors:  S E Antonarakis; H H Kazazian; S H Orkin
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 4.  Alpha-thalassemia.

Authors:  D R Higgs; D J Weatherall
Journal:  Curr Top Hematol       Date:  1983

5.  Multiple arrangements of the human embryonic zeta globin genes.

Authors:  P Winichagoon; D R Higgs; S E Goodbourn; J Lamb; J B Clegg; D J Weatherall
Journal:  Nucleic Acids Res       Date:  1982-10-11       Impact factor: 16.971

6.  Molecular basis of length polymorphism in the human zeta-globin gene complex.

Authors:  S E Goodbourn; D R Higgs; J B Clegg; D J Weatherall
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

7.  Gamma thalassemia resulting from the deletion of a gamma-globin gene.

Authors:  P K Sukumaran; T Nakatsuji; M B Gardiner; A L Reese; J G Gilman; T H Huisman
Journal:  Nucleic Acids Res       Date:  1983-07-11       Impact factor: 16.971

8.  Triplicated alpha-globin loci in humans.

Authors:  M Goossens; A M Dozy; S H Embury; Z Zachariades; M G Hadjiminas; G Stamatoyannopoulos; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  1980-01       Impact factor: 11.205

9.  Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.

Authors:  S H Embury; J A Miller; A M Dozy; Y W Kan; V Chan; D Todd
Journal:  J Clin Invest       Date:  1980-12       Impact factor: 14.808

10.  A novel alpha-globin gene arrangement in man.

Authors:  D R Higgs; J M Old; L Pressley; J B Clegg; D J Weatherall
Journal:  Nature       Date:  1980-04-17       Impact factor: 49.962
View more
  11 in total

1.  Globin genes in Micronesia: origins and affinities of Pacific Island peoples.

Authors:  D F O'Shaughnessy; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025

2.  Population bottlenecks in Polynesia revealed by minisatellites.

Authors:  J Flint; A J Boyce; J J Martinson; J B Clegg
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

3.  Non-deletion haemoglobin H disease in Papua New Guinea.

Authors:  A V Hill; S L Thein; B Mavo; D J Weatherall; J B Clegg
Journal:  J Med Genet       Date:  1987-12       Impact factor: 6.318

4.  Globin genes are useful markers to identify genetic similarities between Fijians and Pacific Islanders from Polynesia and Melanesia.

Authors:  R J Trent; J G Buchanan; A Webb; R P Goundar; L M Seruvatu; K N Mickleson
Journal:  Am J Hum Genet       Date:  1988-04       Impact factor: 11.025

5.  Alpha-globin gene haplotypes in Polynesians: their relationships to population groups and gene rearrangements.

Authors:  M S Hertzberg; K N Mickleson; R J Trent
Journal:  Am J Hum Genet       Date:  1988-12       Impact factor: 11.025

6.  The origins of the Polynesians: an interpretation from mitochondrial lineage analysis.

Authors:  B Sykes; A Leiboff; J Low-Beer; S Tetzner; M Richards
Journal:  Am J Hum Genet       Date:  1995-12       Impact factor: 11.025

7.  VNTR alleles associated with the alpha-globin locus are haplotype and population related.

Authors:  J J Martinson; A J Boyce; J B Clegg
Journal:  Am J Hum Genet       Date:  1994-09       Impact factor: 11.025

8.  A predominantly indigenous paternal heritage for the Austronesian-speaking peoples of insular Southeast Asia and Oceania.

Authors:  C Capelli; J F Wilson; M Richards; M P Stumpf; F Gratrix; S Oppenheimer; P Underhill; V L Pascali; T M Ko; D B Goldstein
Journal:  Am J Hum Genet       Date:  2001-01-22       Impact factor: 11.025

Review 9.  Why are some genetic diseases common? Distinguishing selection from other processes by molecular analysis of globin gene variants.

Authors:  J Flint; R M Harding; J B Clegg; A J Boyce
Journal:  Hum Genet       Date:  1993-03       Impact factor: 4.132

10.  Alpha-globin gene markers identify genetic differences between Australian aborigines and Melanesians.

Authors:  A S Tsintsof; M S Hertzberg; J F Prior; K N Mickleson; R J Trent
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.