Literature DB >> 2983539

Alpha globin gene rearrangements in Polynesians are not associated with malaria.

R J Trent, K N Mickleson, T Wilkinson, J Yakas, R Bluck, M Dixon, A W Liley, H Kronenberg.   

Abstract

Using gene mapping, 16.3% of Polynesians were shown to have alpha thalassemia. These results are surprising since malaria is not found in Polynesia. Moreover, triplicated alpha gene rearrangements were identified in a further 7.7%, a frequency not seen in other populations.

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Year:  1985        PMID： 2983539     DOI： 10.1002/ajh.2830180414

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


  7 in total

1.  Globin genes in Micronesia: origins and affinities of Pacific Island peoples.

Authors:  D F O'Shaughnessy; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1990-01       Impact factor: 11.025

2.  Extremely high frequencies of alpha-globin gene deletion in Madang and on Kar Kar Island, Papua New Guinea.

Authors:  P T Yenchitsomanus; K M Summers; K K Bhatia; J Cattani; P G Board
Journal:  Am J Hum Genet       Date:  1985-07       Impact factor: 11.025

3.  Globin genes in Polynesians have many rearrangements including a recently described gamma gamma gamma gamma/.

Authors:  R J Trent; K N Mickleson; T Wilkinson; J Yakas; M W Dixon; P J Hill; H Kronenberg
Journal:  Am J Hum Genet       Date:  1986-09       Impact factor: 11.025

4.  Polynesian origins and affinities: globin gene variants in eastern Polynesia.

Authors:  A V Hill; B Gentile; J M Bonnardot; J Roux; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1987-05       Impact factor: 11.025

5.  Alpha-globin gene haplotypes in Polynesians: their relationships to population groups and gene rearrangements.

Authors:  M S Hertzberg; K N Mickleson; R J Trent
Journal:  Am J Hum Genet       Date:  1988-12       Impact factor: 11.025

6.  Milk versus medicine for the treatment of iron deficiency anaemia in hospitalised infants.

Authors:  C R Wall; C C Grant; N Taua; C Wilson; J M D Thompson
Journal:  Arch Dis Child       Date:  2005-06-14       Impact factor: 3.791

Review 7.  Why are some genetic diseases common? Distinguishing selection from other processes by molecular analysis of globin gene variants.

Authors:  J Flint; R M Harding; J B Clegg; A J Boyce
Journal:  Hum Genet       Date:  1993-03       Impact factor: 4.132
  7 in total

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