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12 in total

1. Learning from our mistakes: the 'unknown knowns' in fragment screening.

Authors: Ben J Davis; Daniel A Erlanson
Journal: Bioorg Med Chem Lett Date: 2013-03-18 Impact factor: 2.823

2. An Aggregation Advisor for Ligand Discovery.

Authors: John J Irwin; Da Duan; Hayarpi Torosyan; Allison K Doak; Kristin T Ziebart; Teague Sterling; Gurgen Tumanian; Brian K Shoichet
Journal: J Med Chem Date: 2015-08-28 Impact factor: 7.446

3. Chemistry: Chemical con artists foil drug discovery.

Authors: Jonathan Baell; Michael A Walters
Journal: Nature Date: 2014-09-25 Impact factor: 49.962

4. Metal impurities cause false positives in high-throughput screening campaigns.

Authors: Johannes C Hermann; Yingsi Chen; Charles Wartchow; John Menke; Lin Gao; Shelley K Gleason; Nancy-Ellen Haynes; Nathan Scott; Ann Petersen; Stephen Gabriel; Binh Vu; Kelly M George; Arjun Narayanan; Shirley H Li; Hong Qian; Nanda Beatini; Linghao Niu; Qing-Fen Gan
Journal: ACS Med Chem Lett Date: 2012-12-12 Impact factor: 4.345

5. SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV.

Authors: George E Greco; Yoshihiro Matsumoto; Rhys C Brooks; Zhengfei Lu; Michael R Lieber; Alan E Tomkinson
Journal: DNA Repair (Amst) Date: 2016-05-07

6. The drug vehicle and solvent N-methylpyrrolidone is an immunomodulator and antimyeloma compound.

Authors: Jake Shortt; Andy K Hsu; Benjamin P Martin; Karen Doggett; Geoffrey M Matthews; Maria A Doyle; Jason Ellul; Tina E Jockel; Daniel M Andrews; Simon J Hogg; Andrea Reitsma; David Faulkner; P Leif Bergsagel; Marta Chesi; Joan K Heath; William A Denny; Philip E Thompson; Paul J Neeson; David S Ritchie; Grant A McArthur; Ricky W Johnstone
Journal: Cell Rep Date: 2014-05-09 Impact factor: 9.423

7. Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects.

Authors: Joshua E Allen; Gabriel Krigsfeld; Patrick A Mayes; Luv Patel; David T Dicker; Akshal S Patel; Nathan G Dolloff; Evangelos Messaris; Kimberly A Scata; Wenge Wang; Jun-Ying Zhou; Gen Sheng Wu; Wafik S El-Deiry
Journal: Sci Transl Med Date: 2013-02-06 Impact factor: 17.956

8. An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression.

Authors: Mrinal Srivastava; Mridula Nambiar; Sheetal Sharma; Subhas S Karki; G Goldsmith; Mahesh Hegde; Sujeet Kumar; Monica Pandey; Ram K Singh; Pritha Ray; Renuka Natarajan; Madhura Kelkar; Abhijit De; Bibha Choudhary; Sathees C Raghavan
Journal: Cell Date: 2012-12-21 Impact factor: 41.582

9. Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.

Authors: Kilian V M Huber; Eidarus Salah; Branka Radic; Manuela Gridling; Jonathan M Elkins; Alexey Stukalov; Ann-Sofie Jemth; Camilla Göktürk; Kumar Sanjiv; Kia Strömberg; Therese Pham; Ulrika Warpman Berglund; Jacques Colinge; Keiryn L Bennett; Joanna I Loizou; Thomas Helleday; Stefan Knapp; Giulio Superti-Furga
Journal: Nature Date: 2014-04-02 Impact factor: 49.962

Review 10. Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

Authors: Jonathan Bisson; James B McAlpine; J Brent Friesen; Shao-Nong Chen; James Graham; Guido F Pauli
Journal: J Med Chem Date: 2015-10-27 Impact factor: 7.446

6 in total

1. Data Sets Representative of the Structures and Experimental Properties of FDA-Approved Drugs.

Authors: Dominique Douguet
Journal: ACS Med Chem Lett Date: 2018-01-29 Impact factor: 4.345

2. Rigor and reproducibility in rodent behavioral research.

Authors: Maria Gulinello; Heather A Mitchell; Qiang Chang; W Timothy O'Brien; Zhaolan Zhou; Ted Abel; Li Wang; Joshua G Corbin; Surabi Veeraragavan; Rodney C Samaco; Nick A Andrews; Michela Fagiolini; Toby B Cole; Thomas M Burbacher; Jacqueline N Crawley
Journal: Neurobiol Learn Mem Date: 2018-01-04 Impact factor: 2.877

3. Uncertainty Quantification in Alchemical Free Energy Methods.

Authors: Agastya P Bhati; Shunzhou Wan; Yuan Hu; Brad Sherborne; Peter V Coveney
Journal: J Chem Theory Comput Date: 2018-05-02 Impact factor: 6.006

4. Pilot Study to Quantify Palladium Impurities in Lead-like Compounds Following Commonly Used Purification Techniques.

Authors: Maria Chatzopoulou; Katrina S Madden; Liam J Bromhead; Christopher Greaves; Thomas J Cogswell; Solange Da Silva Pinto; Sébastien R G Galan; Irene Georgiou; Matthew S Kennedy; Alice Kennett; Geraint Apps; Angela J Russell; Graham M Wynne
Journal: ACS Med Chem Lett Date: 2022-01-20 Impact factor: 4.345

5. Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.

Authors: Atieh Hajirahimkhan; Obinna Mbachu; Charlotte Simmler; Sarah G Ellis; Huali Dong; Dejan Nikolic; David C Lankin; Richard B van Breemen; Shao-Nong Chen; Guido F Pauli; Birgit M Dietz; Judy L Bolton
Journal: J Nat Prod Date: 2018-04-11 Impact factor: 4.050

6. Reproducible research and GIScience: an evaluation using AGILE conference papers.

Authors: Daniel Nüst; Carlos Granell; Barbara Hofer; Markus Konkol; Frank O Ostermann; Rusne Sileryte; Valentina Cerutti
Journal: PeerJ Date: 2018-07-13 Impact factor: 2.984

6 in total