Literature DB >> 28777791

Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic.

Benjamin Blasco1, Didier Leroy1, David A Fidock2,3.   

Abstract

The global adoption of artemisinin-based combination therapies (ACTs) in the early 2000s heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria. However, several Southeast Asian countries have now reported the emergence of parasites that have decreased susceptibility to artemisinin (ART) derivatives and ACT partner drugs, resulting in increasing rates of treatment failures. Here we review recent advances in understanding how antimalarials act and how resistance develops, and discuss new strategies for effectively combatting resistance, optimizing treatment and advancing the global campaign to eliminate malaria.

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Year:  2017        PMID： 28777791      PMCID： PMC5747363          DOI： 10.1038/nm.4381

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


  181 in total

1.  Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine.

Authors:  Juliana Martha Sá; Olivia Twu; Karen Hayton; Sahily Reyes; Michael P Fay; Pascal Ringwald; Thomas E Wellems
Journal:  Proc Natl Acad Sci U S A       Date:  2009-11-02       Impact factor: 11.205

2.  Endoperoxide Drug Cross-Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed-Clearance Phenotype.

Authors:  A Siriwardana; K Iyengar; P D Roepe
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191

Review 3.  Antimalarial drug resistance in Africa: key lessons for the future.

Authors:  Shannon Takala-Harrison; Miriam K Laufer
Journal:  Ann N Y Acad Sci       Date:  2015-04       Impact factor: 5.691

4.  Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum.

Authors:  Heather J Painter; Joanne M Morrisey; Michael W Mather; Akhil B Vaidya
Journal:  Nature       Date:  2007-03-01       Impact factor: 49.962

5.  Artemisinin resistance in Plasmodium falciparum malaria.

Authors:  Arjen M Dondorp; François Nosten; Poravuth Yi; Debashish Das; Aung Phae Phyo; Joel Tarning; Khin Maung Lwin; Frederic Ariey; Warunee Hanpithakpong; Sue J Lee; Pascal Ringwald; Kamolrat Silamut; Mallika Imwong; Kesinee Chotivanich; Pharath Lim; Trent Herdman; Sen Sam An; Shunmay Yeung; Pratap Singhasivanon; Nicholas P J Day; Niklas Lindegardh; Duong Socheat; Nicholas J White
Journal:  N Engl J Med       Date:  2009-07-30       Impact factor: 91.245

Review 6.  Host targeting of virulence determinants and phosphoinositides in blood stage malaria parasites.

Authors:  Souvik Bhattacharjee; Robert V Stahelin; Kasturi Haldar
Journal:  Trends Parasitol       Date:  2012-10-16

7.  Spread of artemisinin resistance in Plasmodium falciparum malaria.

Authors:  Elizabeth A Ashley; Mehul Dhorda; Rick M Fairhurst; Chanaki Amaratunga; Parath Lim; Seila Suon; Sokunthea Sreng; Jennifer M Anderson; Sivanna Mao; Baramey Sam; Chantha Sopha; Char Meng Chuor; Chea Nguon; Siv Sovannaroth; Sasithon Pukrittayakamee; Podjanee Jittamala; Kesinee Chotivanich; Kitipumi Chutasmit; Chaiyaporn Suchatsoonthorn; Ratchadaporn Runcharoen; Tran Tinh Hien; Nguyen Thanh Thuy-Nhien; Ngo Viet Thanh; Nguyen Hoan Phu; Ye Htut; Kay-Thwe Han; Kyin Hla Aye; Olugbenga A Mokuolu; Rasaq R Olaosebikan; Olaleke O Folaranmi; Mayfong Mayxay; Maniphone Khanthavong; Bouasy Hongvanthong; Paul N Newton; Marie A Onyamboko; Caterina I Fanello; Antoinette K Tshefu; Neelima Mishra; Neena Valecha; Aung Pyae Phyo; Francois Nosten; Poravuth Yi; Rupam Tripura; Steffen Borrmann; Mahfudh Bashraheil; Judy Peshu; M Abul Faiz; Aniruddha Ghose; M Amir Hossain; Rasheda Samad; M Ridwanur Rahman; M Mahtabuddin Hasan; Akhterul Islam; Olivo Miotto; Roberto Amato; Bronwyn MacInnis; Jim Stalker; Dominic P Kwiatkowski; Zbynek Bozdech; Atthanee Jeeyapant; Phaik Yeong Cheah; Tharisara Sakulthaew; Jeremy Chalk; Benjamas Intharabut; Kamolrat Silamut; Sue J Lee; Benchawan Vihokhern; Chanon Kunasol; Mallika Imwong; Joel Tarning; Walter J Taylor; Shunmay Yeung; Charles J Woodrow; Jennifer A Flegg; Debashish Das; Jeffery Smith; Meera Venkatesan; Christopher V Plowe; Kasia Stepniewska; Philippe J Guerin; Arjen M Dondorp; Nicholas P Day; Nicholas J White
Journal:  N Engl J Med       Date:  2014-07-31       Impact factor: 91.245

8.  UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.

Authors:  Michelle Yi-Xiu Lim; Gregory LaMonte; Marcus C S Lee; Christin Reimer; Bee Huat Tan; Victoria Corey; Bianca F Tjahjadi; Adeline Chua; Marie Nachon; René Wintjens; Peter Gedeck; Benoit Malleret; Laurent Renia; Ghislain M C Bonamy; Paul Chi-Lui Ho; Bryan K S Yeung; Eric D Chow; Liting Lim; David A Fidock; Thierry T Diagana; Elizabeth A Winzeler; Pablo Bifani
Journal:  Nat Microbiol       Date:  2016-09-19       Impact factor: 17.745

Review 9.  Association of glucose-6-phosphate dehydrogenase deficiency and malaria: a systematic review and meta-analysis.

Authors:  Evaristus Chibunna Mbanefo; Ali Mahmoud Ahmed; Afaf Titouna; Ahmed Elmaraezy; Nguyen Thi Huyen Trang; Nguyen Phuoc Long; Nguyen Hoang Anh; Tran Diem Nghi; Bui The Hung; Mai Van Hieu; Nguyen Ky Anh; Nguyen Tien Huy; Kenji Hirayama
Journal:  Sci Rep       Date:  2017-04-06       Impact factor: 4.379

10.  Targeting Plasmodium PI(4)K to eliminate malaria.

Authors:  Case W McNamara; Marcus Cs Lee; Chek Shik Lim; Siau Hoi Lim; Jason Roland; Oliver Simon; Bryan Ks Yeung; Arnab K Chatterjee; Susan L McCormack; Micah J Manary; Anne-Marie Zeeman; Koen J Dechering; Tr Santha Kumar; Philipp P Henrich; Kerstin Gagaring; Maureen Ibanez; Nobutaka Kato; Kelli L Kuhen; Christoph Fischli; Advait Nagle; Matthias Rottmann; David M Plouffe; Badry Bursulaya; Stephan Meister; Lucia Rameh; Joerg Trappe; Dorothea Haasen; Martijn Timmerman; Robert W Sauerwein; Rossarin Suwanarusk; Bruce Russell; Laurent Renia; Francois Nosten; David C Tully; Clemens Hm Kocken; Richard J Glynne; Christophe Bodenreider; David A Fidock; Thierry T Diagana; Elizabeth A Winzeler
Journal:  Nature       Date:  2013-11-27       Impact factor: 49.962
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  140 in total

1.  Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria.

Authors:  Andrew Blanshard; Paul Hine
Journal:  Cochrane Database Syst Rev       Date:  2021-01-15

2.  Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro.

Authors:  Lais Pessanha de Carvalho; Thaisa Lucas Sandri; Edésio José Tenório de Melo; Rolf Fendel; Peter G Kremsner; Benjamin Mordmüller; Jana Held
Journal:  Antimicrob Agents Chemother       Date:  2019-07-25       Impact factor: 5.191

3.  Tafenoquine: A Step toward Malaria Elimination.

Authors:  Kuan-Yi Lu; Emily R Derbyshire
Journal:  Biochemistry       Date:  2020-02-24       Impact factor: 3.162

4.  Brief Report: Antimalarial Benefit of HIV Antiretroviral Therapy in Areas of Low to Moderate Malaria Transmission Intensity.

Authors:  Scott Greenhalgh; Charlotte V Hobbs; Sunil Parikh
Journal:  J Acquir Immune Defic Syndr       Date:  2018-10-01       Impact factor: 3.731

5.  Approval of Tafenoquine for Malaria Chemoprophylaxis.

Authors:  Jonathan D Berman
Journal:  Am J Trop Med Hyg       Date:  2019-06       Impact factor: 2.345

Review 6.  Elucidating Mechanisms of Drug-Resistant Plasmodium falciparum.

Authors:  Leila S Ross; David A Fidock
Journal:  Cell Host Microbe       Date:  2019-07-10       Impact factor: 21.023

7.  Remodeling of the malaria parasite and host human red cell by vesicle amplification that induces artemisinin resistance.

Authors:  Souvik Bhattacharjee; Isabelle Coppens; Alassane Mbengue; Niraja Suresh; Mehdi Ghorbal; Zdenek Slouka; Innocent Safeukui; Hsin-Yao Tang; David W Speicher; Robert V Stahelin; Narla Mohandas; Kasturi Haldar
Journal:  Blood       Date:  2018-01-23       Impact factor: 22.113

8.  Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype.

Authors:  Megan R Ansbro; Zina Itkin; Lu Chen; Gergely Zahoranszky-Kohalmi; Chanaki Amaratunga; Olivo Miotto; Tyler Peryea; Charlotte V Hobbs; Seila Suon; Juliana M Sá; Arjen M Dondorp; Rob W van der Pluijm; Thomas E Wellems; Anton Simeonov; Richard T Eastman
Journal:  ACS Pharmacol Transl Sci       Date:  2020-11-02

9.  Malaria parasite evolution in a test tube.

Authors:  Jane M Carlton
Journal:  Science       Date:  2018-01-12       Impact factor: 47.728

Review 10.  Role of phospholipid synthesis in the development and differentiation of malaria parasites in the blood.

Authors:  Nicole Kilian; Jae-Yeon Choi; Dennis R Voelker; Choukri Ben Mamoun
Journal:  J Biol Chem       Date:  2018-10-04       Impact factor: 5.157
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