Literature DB >> 28726093

The fluorescence lifetime of lipofuscin granule fluorophores contained in the retinal pigment epithelium cells from human cadaver eyes in normal state and in the case of visualized pathology.

M A Yakovleva1, T B Feldman2,3, P M Arbukhanova4, S A Borzenok4, V A Kuzmin2, M A Ostrovsky2,3.   

Abstract

A comparative analysis of fluorescence lifetime of lipofuscin granule fluorophores contained in the retinal pigment epithelium cells from human cadaver eyes in normal state and in the case of visualized pathology was carried out. Measurements of fluorescence lifetimes of bis-retinoids and their photooxidation and photodegradation products were carried out using the method of counting time-correlated photons. Comparative analysis showed that, in the case of visualized pathology, the contribution of photooxidation and photodegradation products of bis-retinoids to the total fluorescence of the retinal pigment epithelium cell suspension increases in comparison with the norm.

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Year:  2017        PMID： 28726093     DOI： 10.1134/S1607672917030231

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  10 in total

1.  A simple method for the isolation and purification of total lipides from animal tissues.

Authors:  J FOLCH; M LEES; G H SLOANE STANLEY
Journal:  J Biol Chem       Date:  1957-05       Impact factor: 5.157

Review 2.  A2E: a component of ocular lipofuscin.

Authors:  Laura E Lamb; John D Simon
Journal:  Photochem Photobiol       Date:  2004-02       Impact factor: 3.421

3.  Towards metabolic mapping of the human retina.

Authors:  D Schweitzer; S Schenke; M Hammer; F Schweitzer; S Jentsch; E Birckner; W Becker; A Bergmann
Journal:  Microsc Res Tech       Date:  2007-05       Impact factor: 2.769

4.  [Comparison of parameters of time-resolved autofluorescence between healthy subjects and patients suffering from early AMD].

Authors:  D Schweitzer; S Quick; S Schenke; M Klemm; S Gehlert; M Hammer; S Jentsch; J Fischer
Journal:  Ophthalmologe       Date:  2009-08       Impact factor: 1.059

5.  Estimation of fluorescence lifetime of lipofuscin fluorophores contained in lipofuscin granules of retinal pigment epithelium of human cadaver eyes without signs of pathology.

Authors:  M A Yakovleva; T B Feldman; P M Arbukhanova; S A Borzenok; V A Kuzmin; M A Ostrovsky
Journal:  Dokl Biochem Biophys       Date:  2017-04-19       Impact factor: 0.788

6.  Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration.

Authors:  Yalin Wu; Emiko Yanase; Xidong Feng; Marshall M Siegel; Janet R Sparrow
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-05       Impact factor: 11.205

Review 7.  The bisretinoids of retinal pigment epithelium.

Authors:  Janet R Sparrow; Emily Gregory-Roberts; Kazunori Yamamoto; Anna Blonska; Shanti Kaligotla Ghosh; Keiko Ueda; Jilin Zhou
Journal:  Prog Retin Eye Res       Date:  2011-12-22       Impact factor: 21.198

Review 8.  Phospholipid meets all-trans-retinal: the making of RPE bisretinoids.

Authors:  Janet R Sparrow; Yalin Wu; Chul Y Kim; Jilin Zhou
Journal:  J Lipid Res       Date:  2009-08-07       Impact factor: 5.922

9.  Time-resolved autofluorescence imaging of human donor retina tissue from donors with significant extramacular drusen.

Authors:  Dietrich Schweitzer; Elizabeth R Gaillard; James Dillon; Robert F Mullins; Stephen Russell; Birgit Hoffmann; Sven Peters; Martin Hammer; Christoph Biskup
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-06-08       Impact factor: 4.799

10.  Changes in spectral properties and composition of lipofuscin fluorophores from human-retinal-pigment epithelium with age and pathology.

Authors:  Tatiana B Feldman; Marina A Yakovleva; Patimat M Arbukhanova; Sergey A Borzenok; Alexey S Kononikhin; Igor A Popov; Evgeny N Nikolaev; Mikhail A Ostrovsky
Journal:  Anal Bioanal Chem       Date:  2014-12-04       Impact factor: 4.142
  10 in total
  1 in total

1.  Spectral analysis of fundus autofluorescence pattern as a tool to detect early stages of degeneration in the retina and retinal pigment epithelium.

Authors:  Tatiana B Feldman; Marina A Yakovleva; Andrey V Larichev; Patimat M Arbukhanova; Alexandra Sh Radchenko; Sergey A Borzenok; Vladimir A Kuzmin; Mikhail A Ostrovsky
Journal:  Eye (Lond)       Date:  2018-05-22       Impact factor: 3.775
  1 in total

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