PURPOSE: To assess the feasibility and performance of conical k-space trajectory free-breathing ultrashort echo time (UTE) chest magnetic resonance imaging (MRI) versus four-dimensional (4D) flow and effects of 50% data subsampling and soft-gated motion correction. MATERIALS AND METHODS: Thirty-two consecutive children who underwent both 4D flow and UTE ferumoxytol-enhanced chest MR (mean age: 5.4 years, range: 6 days to 15.7 years) in one 3T exam were recruited. From UTE k-space data, three image sets were reconstructed: 1) one with all data, 2) one using the first 50% of data, and 3) a final set with soft-gating motion correction, leveraging the signal magnitude immediately after each excitation. Two radiologists in blinded fashion independently scored image quality of anatomical landmarks on a 5-point scale. Ratings were compared using Wilcoxon rank-sum, Wilcoxon signed-ranks, and Kruskal-Wallis tests. Interobserver agreement was assessed with the intraclass correlation coefficient (ICC). RESULTS: For fully sampled UTE, mean scores for all structures were ≥4 (good-excellent). Full UTE surpassed 4D flow for lungs and airways (P < 0.001), with similar pulmonary artery (PA) quality (P = 0.62). 50% subsampling only slightly degraded all landmarks (P < 0.001), as did motion correction. Subsegmental PA visualization was possible in >93% scans for all techniques (P = 0.27). Interobserver agreement was excellent for combined scores (ICC = 0.83). CONCLUSION: High-quality free-breathing conical UTE chest MR is feasible, surpassing 4D flow for lungs and airways, with equivalent PA visualization. Data subsampling only mildly degraded images, favoring lesser scan times. Soft-gating motion correction overall did not improve image quality. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:200-209.
PURPOSE: To assess the feasibility and performance of conical k-space trajectory free-breathing ultrashort echo time (UTE) chest magnetic resonance imaging (MRI) versus four-dimensional (4D) flow and effects of 50% data subsampling and soft-gated motion correction. MATERIALS AND METHODS: Thirty-two consecutive children who underwent both 4D flow and UTE ferumoxytol-enhanced chest MR (mean age: 5.4 years, range: 6 days to 15.7 years) in one 3T exam were recruited. From UTE k-space data, three image sets were reconstructed: 1) one with all data, 2) one using the first 50% of data, and 3) a final set with soft-gating motion correction, leveraging the signal magnitude immediately after each excitation. Two radiologists in blinded fashion independently scored image quality of anatomical landmarks on a 5-point scale. Ratings were compared using Wilcoxon rank-sum, Wilcoxon signed-ranks, and Kruskal-Wallis tests. Interobserver agreement was assessed with the intraclass correlation coefficient (ICC). RESULTS: For fully sampled UTE, mean scores for all structures were ≥4 (good-excellent). Full UTE surpassed 4D flow for lungs and airways (P < 0.001), with similar pulmonary artery (PA) quality (P = 0.62). 50% subsampling only slightly degraded all landmarks (P < 0.001), as did motion correction. Subsegmental PA visualization was possible in >93% scans for all techniques (P = 0.27). Interobserver agreement was excellent for combined scores (ICC = 0.83). CONCLUSION: High-quality free-breathing conical UTE chest MR is feasible, surpassing 4D flow for lungs and airways, with equivalent PA visualization. Data subsampling only mildly degraded images, favoring lesser scan times. Soft-gating motion correction overall did not improve image quality. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:200-209.
Authors: Mark C Liszewski; F William Hersman; Talissa A Altes; Yoshiharu Ohno; Pierluigi Ciet; Simon K Warfield; Edward Y Lee Journal: Radiol Clin North Am Date: 2013-07 Impact factor: 2.303
Authors: Peter Bannas; Laura C Bell; Kevin M Johnson; Mark L Schiebler; Christopher J François; Utaroh Motosugi; Daniel Consigny; Scott B Reeder; Scott K Nagle Journal: Radiology Date: 2015-09-30 Impact factor: 11.105
Authors: Joseph Y Cheng; Tao Zhang; Nichanan Ruangwattanapaisarn; Marcus T Alley; Martin Uecker; John M Pauly; Michael Lustig; Shreyas S Vasanawala Journal: J Magn Reson Imaging Date: 2014-10-20 Impact factor: 4.813
Authors: Tao Zhang; Joseph Y Cheng; Yuxin Chen; Dwight G Nishimura; John M Pauly; Shreyas S Vasanawala Journal: Magn Reson Med Date: 2015-07-29 Impact factor: 4.668
Authors: Wieying Kuo; Pierluigi Ciet; Harm A W M Tiddens; Wei Zhang; R Paul Guillerman; Marcel van Straten Journal: Am J Respir Crit Care Med Date: 2014-06-01 Impact factor: 21.405
Authors: Mario O Malavé; Corey A Baron; Nii Okai Addy; Joseph Y Cheng; Phillip C Yang; Bob S Hu; Dwight G Nishimura Journal: Magn Reson Med Date: 2018-10-29 Impact factor: 4.668
Authors: David Y Zeng; Jamil Shaikh; Signy Holmes; Ryan L Brunsing; John M Pauly; Dwight G Nishimura; Shreyas S Vasanawala; Joseph Y Cheng Journal: Magn Reson Med Date: 2019-05-22 Impact factor: 4.668
Authors: Frank Ong; Xucheng Zhu; Joseph Y Cheng; Kevin M Johnson; Peder E Z Larson; Shreyas S Vasanawala; Michael Lustig Journal: Magn Reson Med Date: 2020-04-09 Impact factor: 4.668
Authors: Jason C Woods; Jim M Wild; Mark O Wielpütz; John P Clancy; Hiroto Hatabu; Hans-Ulrich Kauczor; Edwin J R van Beek; Talissa A Altes Journal: J Magn Reson Imaging Date: 2019-12-17 Impact factor: 4.813