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Literature DB >> 2855467

Viral and cellular oncogenes in papillomavirus-associated cancers.

Abstract

Papillomaviruses are one of several factors implicated in the aetiology of squamous cell carcinomas both in man and in animals. Their potential for malignant transformation is fully expressed when co-operation takes place between viral functions, cellular functions and chemical or physical co-carcinogens. This review presents a brief description of the viral transforming genes and of the cellular genes involved in transformation, and attempts to analyse how the co-operation between the two sets of genes is achieved.

Entities: Disease Species

Mesh：

Year: 1988 PMID： 2855467 PMCID： PMC2149113

Source DB: PubMed Journal: Br J Cancer Suppl ISSN： 0306-9443

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References

53 in total

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Authors: J M Berg
Journal: Science Date: 1986-04-25 Impact factor: 47.728

2. Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product.

Authors: B A Spalholz; Y C Yang; P M Howley
Journal: Cell Date: 1985-08 Impact factor: 41.582

3. E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene.

Authors: J T Schiller; W C Vass; K H Vousden; D R Lowy
Journal: J Virol Date: 1986-01 Impact factor: 5.103

Review 4. Growth factors and cancer.

Authors: A S Goustin; E B Leof; G D Shipley; H L Moses
Journal: Cancer Res Date: 1986-03 Impact factor: 12.701

10. The presence of bovine papillomavirus type 4 DNA is not required for the progression to, or the maintenance of, the malignant state in cancers of the alimentary canal in cattle.

Authors: M S Campo; M H Moar; M L Sartirana; I M Kennedy; W F Jarrett
Journal: EMBO J Date: 1985-07 Impact factor: 11.598

Viral and cellular oncogenes in papillomavirus-associated cancers.

1. Potential metal-binding domains in nucleic acid binding proteins.

2. Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product.

3. E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene.

Review 4. Growth factors and cancer.

5. Transforming activity of human papillomavirus type 16 DNA sequence in a cervical cancer.

Review 6. Papillomaviruses and their involvement in oncogenesis.

7. Identification of the protein encoded by the E6 transforming gene of bovine papillomavirus.

8. Papillomavirus genomes in human cervical tumors: analysis of their transcriptional activity.

9. The physical state of human papillomavirus type 16 DNA in benign and malignant genital tumours.

10. The presence of bovine papillomavirus type 4 DNA is not required for the progression to, or the maintenance of, the malignant state in cancers of the alimentary canal in cattle.