Hirokazu Hasegawa1, Ryuichiro Ashikaga2, Kaoru Okajima2, Tetsuya Wakayama3, Mitsuharu Miyoshi3, Yasumasa Nishimura4, Takamichi Murakami5. 1. Department of Radiology, Nara Hospital, Kindai University Faculty of Medicine, 1248-1, Otodacho, Ikoma, Nara, 630-0293, Japan. hhmmk2000@gmail.com. 2. Department of Radiology, Nara Hospital, Kindai University Faculty of Medicine, 1248-1, Otodacho, Ikoma, Nara, 630-0293, Japan. 3. GE Healthcare Japan, MR Applications and Workflow, Asia Pacific, 4-7-127, Asahigaoka, Hino, Tokyo, 191-8503, Japan. 4. Department of Radiation Oncology, Kindai University Faculty of Medicine, 377-2 Ohnohigashi, Osaka-sayama, Osaka, 589-5811, Japan. 5. Department of Radiology, Kindai University Faculty of Medicine, 377-2 Ohnohigashi, Osaka-sayama, Osaka, 589-5811, Japan.
Abstract
PURPOSE: This study aimed to compare the detectability of neoplastic lesion enhancement after gadolinium-based contrast media injection in three-dimensional T1-weighted black blood Cube (3D-T1W BB Cube) and three-dimensional T1-weighted fast spoiled gradient-echo (3D-T1W fast SPGR) images obtained with 1.5-T magnetic resonance imaging (MRI). MATERIALS AND METHODS: Phantom and clinical studies were performed to compare the lesion detectability and contrast ratio (CR) between 3D-T1W BB Cube and 3D-T1W fast SPGR pulse sequences. RESULTS: In the phantom study, the CRs for 3D-T1W BB Cube and 3D-T1W fast SPGR were equivalent at low gadolinium concentrations (0.125-1.25 mmol/l). In the clinical study, the detectability in the two modalities was similar for enhanced lesions ≥5 mm, but was significantly better in 3D-T1W BB Cube for lesions <5 mm (p = 0.011). Similarly, the CRs in both modalities were similar for lesions ≥5 mm (0.66 ± 0.36 vs. 0.56 ± 0.30, p = 0.153), but significantly lower in 3D-T1W BB Cube images for lesions <5 mm (0.29 ± 0.19 vs. 0.39 ± 0.21, p = 0.006). CONCLUSIONS: Contrast 3D-T1W BB Cube imaging appears more sensitive than 3D-T1W fast SPGR imaging for detecting neoplastic lesion enhancement in the clinical setting using a 1.5-T MRI scanner, particularly for lesions <5 mm in diameter.
PURPOSE: This study aimed to compare the detectability of neoplastic lesion enhancement after gadolinium-based contrast media injection in three-dimensional T1-weighted black blood Cube (3D-T1W BB Cube) and three-dimensional T1-weighted fast spoiled gradient-echo (3D-T1W fast SPGR) images obtained with 1.5-T magnetic resonance imaging (MRI). MATERIALS AND METHODS: Phantom and clinical studies were performed to compare the lesion detectability and contrast ratio (CR) between 3D-T1W BB Cube and 3D-T1W fast SPGR pulse sequences. RESULTS: In the phantom study, the CRs for 3D-T1W BB Cube and 3D-T1W fast SPGR were equivalent at low gadolinium concentrations (0.125-1.25 mmol/l). In the clinical study, the detectability in the two modalities was similar for enhanced lesions ≥5 mm, but was significantly better in 3D-T1W BB Cube for lesions <5 mm (p = 0.011). Similarly, the CRs in both modalities were similar for lesions ≥5 mm (0.66 ± 0.36 vs. 0.56 ± 0.30, p = 0.153), but significantly lower in 3D-T1W BB Cube images for lesions <5 mm (0.29 ± 0.19 vs. 0.39 ± 0.21, p = 0.006). CONCLUSIONS: Contrast 3D-T1W BB Cube imaging appears more sensitive than 3D-T1W fast SPGR imaging for detecting neoplastic lesion enhancement in the clinical setting using a 1.5-T MRI scanner, particularly for lesions <5 mm in diameter.
Entities:
Keywords:
Black blood (BB) imaging; Contrast enhancement; Cube; Magnetic resonance imaging; Spoiled gradient echo (SPGR)
Authors: Miriam Reichert; John N Morelli; Val M Runge; Ai Tao; Ruediger von Ritschl; Andreas von Ritschl; Abraham Padua; James E Dix; Michael J Marra; Stefan O Schoenberg; Ulrike I Attenberger Journal: Invest Radiol Date: 2013-01 Impact factor: 6.016