Literature DB >> 2849047

Characterization of porphyrin interactions with peripheral type benzodiazepine receptors.

A Verma1, S H Snyder.   

Abstract

We have examined organ and species variations in interactions of porphyrins with peripheral-type benzodiazepine receptors and explored structure-activity requirements for porphyrin-receptor interactions. Whereas potency of the benzodiazepine RO5-4864 varies several orders of magnitude in competing for receptors in different organs and species, effects of porphyrins and the isoquinoline carboxamide PK11195 are relatively constant. The structural requirements determining porphyrin affinity for benzodiazepine binding sites are fairly strict. The most potent porphyrins are those with prominent physiological functions.

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Year:  1988        PMID： 2849047

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


  14 in total

Review 1.  The peripheral benzodiazepine receptors: a review.

Authors:  A Beurdeley-Thomas; L Miccoli; S Oudard; B Dutrillaux; M F Poupon
Journal:  J Neurooncol       Date:  2000       Impact factor: 4.130

2.  Regulation of the inner membrane mitochondrial permeability transition by the outer membrane translocator protein (peripheral benzodiazepine receptor).

Authors:  Justina Sileikyte; Valeria Petronilli; Alessandra Zulian; Federica Dabbeni-Sala; Giuseppe Tognon; Peter Nikolov; Paolo Bernardi; Fernanda Ricchelli
Journal:  J Biol Chem       Date:  2010-11-09       Impact factor: 5.157

Review 3.  Electrophysiology of the inner mitochondrial membrane.

Authors:  M Zoratti; I Szabó
Journal:  J Bioenerg Biomembr       Date:  1994-10       Impact factor: 2.945

4.  Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands.

Authors:  K W Kinnally; D B Zorov; Y N Antonenko; S H Snyder; M W McEnery; H Tedeschi
Journal:  Proc Natl Acad Sci U S A       Date:  1993-02-15       Impact factor: 11.205

Review 5.  Molecular mechanisms of peripheral benzodiazepine receptors.

Authors:  S H Snyder; M W McEnery; A Verma
Journal:  Neurochem Res       Date:  1990-02       Impact factor: 3.996

6.  Photodynamic tumor therapy: mitochondrial benzodiazepine receptors as a therapeutic target.

Authors:  A Verma; S L Facchina; D J Hirsch; S Y Song; L F Dillahey; J R Williams; S H Snyder
Journal:  Mol Med       Date:  1998-01       Impact factor: 6.354

Review 7.  The mitochondrial benzodiazepine receptor: evidence for association with the voltage-dependent anion channel (VDAC).

Authors:  M W McEnery
Journal:  J Bioenerg Biomembr       Date:  1992-02       Impact factor: 2.945

8.  Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier.

Authors:  M W McEnery; A M Snowman; R R Trifiletti; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

9.  Pharmacological chaperone for the structured domain of human prion protein.

Authors:  Andrew J Nicoll; Clare R Trevitt; M Howard Tattum; Emmanuel Risse; Emma Quarterman; Amaurys Avila Ibarra; Connor Wright; Graham S Jackson; Richard B Sessions; Mark Farrow; Jonathan P Waltho; Anthony R Clarke; John Collinge
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-27       Impact factor: 11.205

10.  Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)).

Authors:  Justina Šileikytė; Elizabeth Blachly-Dyson; Randall Sewell; Andrea Carpi; Roberta Menabò; Fabio Di Lisa; Fernanda Ricchelli; Paolo Bernardi; Michael Forte
Journal:  J Biol Chem       Date:  2014-04-01       Impact factor: 5.157
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