Literature DB >> 10896204

The peripheral benzodiazepine receptors: a review.

A Beurdeley-Thomas1, L Miccoli, S Oudard, B Dutrillaux, M F Poupon.   

Abstract

Peripheral benzodiazepine receptors (PBRs) have been identified in various peripheral tissues as well as in glial cells in the brain. This review describes the tissue and subcellular distribution of the PBR in mammalian tissues and analyzes its many putative endogenous ligands. It deals with the pharmacological, structural and molecular characterization of the PBR, the proteins associated with the receptor (VDAC, ANC, PRAX-1) and their roles in cell growth and differentiation, cancer, steroid biosynthesis, and other physiological roles.

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Year:  2000        PMID： 10896204     DOI： 10.1023/a:1006456715525

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  107 in total

1.  An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain.

Authors:  A Guidotti; G Toffano; E Costa
Journal:  Nature       Date:  1978-10-12       Impact factor: 49.962

Review 2.  Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH.

Authors:  E R Simpson; M R Waterman
Journal:  Annu Rev Physiol       Date:  1988       Impact factor: 19.318

Review 3.  Molecular and functional properties of mitochondrial benzodiazepine receptors.

Authors:  K E Krueger
Journal:  Biochim Biophys Acta       Date:  1995-12-20

4.  Characterization of peripheral-type benzodiazepine binding sites in brain using [3H]Ro 5-4864.

Authors:  P J Marangos; J Patel; J P Boulenger; R Clark-Rosenberg
Journal:  Mol Pharmacol       Date:  1982-07       Impact factor: 4.436

5.  Tranquillizers can block mitogenesis in 3T3 cells and induce differentiation in Friend cells.

Authors:  G D Clarke; P J Ryan
Journal:  Nature       Date:  1980-09-11       Impact factor: 49.962

Review 6.  Molecular biology of GABAA receptors.

Authors:  R W Olsen; A J Tobin
Journal:  FASEB J       Date:  1990-03       Impact factor: 5.191

Review 7.  Peripheral-type benzodiazepine receptors: a second site of action for benzodiazepines.

Authors:  K E Krueger
Journal:  Neuropsychopharmacology       Date:  1991-06       Impact factor: 7.853

8.  Antiproliferative action of benzodiazepines in cultured brain cells is not mediated through the peripheral-type benzodiazepine acceptor.

Authors:  A M Gorman; G B O'Beirne; C M Regan; D C Williams
Journal:  J Neurochem       Date:  1989-09       Impact factor: 5.372

9.  Benzodiazepines that bind at peripheral sites inhibit cell proliferation.

Authors:  J K Wang; J I Morgan; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

Review 10.  Receptors for the age of anxiety: pharmacology of the benzodiazepines.

Authors:  J F Tallman; S M Paul; P Skolnick; D W Gallager
Journal:  Science       Date:  1980-01-18       Impact factor: 47.728
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  16 in total

Review 1.  Additives to local anesthetics for peripheral nerve blockade.

Authors:  Chad M Brummett; Brian A Williams
Journal:  Int Anesthesiol Clin       Date:  2011

2.  Benzodiazepine Use and Risk of Developing Alzheimer's Disease: A Case-Control Study Based on Swiss Claims Data.

Authors:  Fabienne A Biétry; Alena M Pfeil; Oliver Reich; Matthias Schwenkglenks; Christoph R Meier
Journal:  CNS Drugs       Date:  2017-03       Impact factor: 5.749

3.  Effect of adjuvant drugs on the action of local anesthetics in isolated rat sciatic nerves.

Authors:  Eser Yilmaz-Rastoder; Michael S Gold; Karen A Hough; G F Gebhart; Brian A Williams
Journal:  Reg Anesth Pain Med       Date:  2012 Jul-Aug       Impact factor: 6.288

4.  Antiproliferative effect of peripheral benzodiazepine receptor antagonist PK11195 in rat mammary tumor cells.

Authors:  Sutapa Mukhopadhyay; Bobby Guillory; Shyamali Mukherjee; Salil K Das
Journal:  Mol Cell Biochem       Date:  2010-03-04       Impact factor: 3.396

5.  Identification of genes involved in the host response to neurovirulent alphavirus infection.

Authors:  C Johnston; W Jiang; T Chu; B Levine
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

6.  Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand.

Authors:  Atsuko Kita; Hitoshi Kohayakawa; Tomoko Kinoshita; Yoshiaki Ochi; Keiko Nakamichi; Satoshi Kurumiya; Kiyoshi Furukawa; Makoto Oka
Journal:  Br J Pharmacol       Date:  2004-07-12       Impact factor: 8.739

Review 7.  VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis.

Authors:  Leo Veenman; Yulia Shandalov; Moshe Gavish
Journal:  J Bioenerg Biomembr       Date:  2008-06       Impact factor: 2.945

8.  Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme.

Authors:  Stéphane Oudard; Antoine Carpentier; Eugeniu Banu; François Fauchon; Denis Celerier; Marie F Poupon; Bernard Dutrillaux; Jean M Andrieu; Jean Y Delattre
Journal:  J Neurooncol       Date:  2003-05       Impact factor: 4.130

9.  The Drosophila gene Start1: a putative cholesterol transporter and key regulator of ecdysteroid synthesis.

Authors:  Guenther E Roth; Mathias S Gierl; Lars Vollborn; Martin Meise; Ruth Lintermann; Guenter Korge
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-26       Impact factor: 11.205

10.  Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility.

Authors:  Neal B Blatt; Jeffrey J Bednarski; Roscoe E Warner; Francesco Leonetti; Kathryn M Johnson; Anthony Boitano; Raymond Yung; Bruce C Richardson; Kent J Johnson; Jonathan A Ellman; Anthony W Opipari; Gary D Glick
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808
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