AIM: The aim of our study is to compare the outcomes of laparoscopic resection (LR) and open resection (OR) for colorectal cancer surgery evaluating lymph node assessment. It may be important to remove and examine an adequate number of lymph nodes because a more extensive nodal resection has been associated to higher survival rate and lower recurrences. PATIENTS AND METHODS: 150 patients (74 females and 76 males) with colorectal cancer were enrolled and analyzed from January 2006 to March 2010 in our Unit. 100 procedures were performed with traditional laparotomy and 50 procedures laparoscopically. A strict follow-up was scheduled every 1-3-6 months after surgery and, therefore, every year. RESULTS: Laparoscopic techniques require a longer operating time. 2484 total lymph nodes examined with a mean of 16,56 removed per resection in all procedures. 1632 lymph nodes were removed during open procedures and 852 removed during laparoscopy. The scheduled follow-up demonstrated that local recurrence and distant metastasis presented with no significant differences between two groups and overall survival and disease-free survival were assessed over 5 year in 80% of patients. CONCLUSIONS: According to our experience, laparoscopic colorectal surgery is safe and feasible, with better short-term outcomes and oncological adequacy comparable to open approach.
AIM: The aim of our study is to compare the outcomes of laparoscopic resection (LR) and open resection (OR) for colorectal cancer surgery evaluating lymph node assessment. It may be important to remove and examine an adequate number of lymph nodes because a more extensive nodal resection has been associated to higher survival rate and lower recurrences. PATIENTS AND METHODS: 150 patients (74 females and 76 males) with colorectal cancer were enrolled and analyzed from January 2006 to March 2010 in our Unit. 100 procedures were performed with traditional laparotomy and 50 procedures laparoscopically. A strict follow-up was scheduled every 1-3-6 months after surgery and, therefore, every year. RESULTS: Laparoscopic techniques require a longer operating time. 2484 total lymph nodes examined with a mean of 16,56 removed per resection in all procedures. 1632 lymph nodes were removed during open procedures and 852 removed during laparoscopy. The scheduled follow-up demonstrated that local recurrence and distant metastasis presented with no significant differences between two groups and overall survival and disease-free survival were assessed over 5 year in 80% of patients. CONCLUSIONS: According to our experience, laparoscopic colorectal surgery is safe and feasible, with better short-term outcomes and oncological adequacy comparable to open approach.
Authors: Steve Kwon; Richard Billingham; Ellen Farrokhi; Michael Florence; Daniel Herzig; Karen Horvath; Terry Rogers; Scott Steele; Rebecca Symons; Richard Thirlby; Mark Whiteford; David R Flum Journal: J Am Coll Surg Date: 2012-04-24 Impact factor: 6.113
Authors: Marco Braga; Nicolò Pecorelli; Matteo Frasson; Andrea Vignali; Walter Zuliani; Valerio Di Carlo Journal: World J Gastrointest Oncol Date: 2011-03-15
Authors: H Jacob Bonjer; Wim C J Hop; Heidi Nelson; Daniel J Sargent; Antonio M Lacy; Antoni Castells; Pierre J Guillou; Helen Thorpe; Julia Brown; Salvadora Delgado; Esther Kuhrij; Eva Haglind; Lars Påhlman Journal: Arch Surg Date: 2007-03
Authors: Nancy N Baxter; Dan J Virnig; David A Rothenberger; Arden M Morris; Jose Jessurun; Beth A Virnig Journal: J Natl Cancer Inst Date: 2005-02-02 Impact factor: 13.506
Authors: Giuseppe Grosso; Antonio Biondi; Stefano Marventano; Antonio Mistretta; Giorgio Calabrese; Francesco Basile Journal: BMC Surg Date: 2012-11-15 Impact factor: 2.102
Authors: Antonio Biondi; Gianluca Di Mauro; Riccardo Morici; Giuseppe Sangiorgio; Marco Vacante; Francesco Basile Journal: J Clin Med Date: 2021-12-19 Impact factor: 4.241