Literature DB >> 28353049

Single-stage Acetabular Revision During Two-stage THA Revision for Infection is Effective in Selected Patients.

Bernd Fink1,2, Michael Schlumberger3, Damian Oremek3.   

Abstract

BACKGROUND: The treatment of periprosthetic infections of hip arthroplasties typically involves use of either a single- or two-stage (with implantation of a temporary spacer) revision surgery. In patients with severe acetabular bone deficiencies, either already present or after component removal, spacers cannot be safely implanted. In such hips where it is impossible to use spacers and yet a two-stage revision of the prosthetic stem is recommended, we have combined a two-stage revision of the stem with a single revision of the cup. To our knowledge, this approach has not been reported before. QUESTIONS/PURPOSES: (1) What proportion of patients treated with single-stage acetabular reconstruction as part of a two-stage revision for an infected THA remain free from infection at 2 or more years? (2) What are the Harris hip scores after the first stage and at 2 years or more after the definitive reimplantation?
METHODS: Between June 2009 and June 2014, we treated all patients undergoing surgical treatment for an infected THA using a single-stage acetabular revision as part of a two-stage THA exchange if the acetabular defect classification was Paprosky Types 2B, 2C, 3A, 3B, or pelvic discontinuity and a two-stage procedure was preferred for the femur. The procedure included removal of all components, joint débridement, definitive acetabular reconstruction (with a cage to bridge the defect, and a cemented socket), and a temporary cemented femoral component at the first stage; the second stage consisted of repeat joint and femoral débridement and exchange of the femoral component to a cementless device. During the period noted, 35 patients met those definitions and were treated with this approach. No patients were lost to followup before 2 years; mean followup was 42 months (range, 24-84 months). The clinical evaluation was performed with the Harris hip scores and resolution of infection was assessed by the absence of clinical signs of infection and a C-reactive protein level less than 10 mg/L. All patients were assessed before surgery, between stages, every 3 months during the first year after surgery, every 6 months during the second year postoperative, and at latest followup, and were retrospectively drawn from a longitudinally maintained institutional database.
RESULTS: Thirty-four of 35 patients (97.2%; 95% CI, 85.4%-99.5%) appeared free of infection by criteria of Masri et al. and Zimmerli et al. at latest followup. The Harris hip score was 61 ± 13 points after the first operation and 82 ± 16 points 2 years after the second operation.
CONCLUSIONS: This technique is a promising treatment option for periprosthetic infections of the hip in which substantial acetabular defects exclude implantation of a normal spacer and a two-stage revision of the femoral component is favored. LEVEL OF EVIDENCE: Level IV, therapeutic study.

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Year:  2017        PMID: 28353049      PMCID: PMC5498382          DOI: 10.1007/s11999-017-5334-5

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  36 in total

1.  The reliability of diagnosis of infection during revision arthroplasties.

Authors:  P Virolainen; H Lähteenmäki; A Hiltunen; E Sipola; O Meurman; O Nelimarkka
Journal:  Scand J Surg       Date:  2002       Impact factor: 2.360

2.  Comparison of one-stage revision with antibiotic cement versus two-stage revision results for infected total hip arthroplasty.

Authors:  Ho-Rim Choi; Young-Min Kwon; Andrew A Freiberg; Henrik Malchau
Journal:  J Arthroplasty       Date:  2013-08-20       Impact factor: 4.757

3.  The Transfemoral Approach for Removal of Well-Fixed Femoral Stems in 2-Stage Septic Hip Revision.

Authors:  Bernd Fink; Damian Oremek
Journal:  J Arthroplasty       Date:  2015-11-26       Impact factor: 4.757

4.  Cementless two-staged total hip arthroplasty for deep periprosthetic infection.

Authors:  Matthew J Kraay; Victor M Goldberg; Steven J Fitzgerald; Michael J Salata
Journal:  Clin Orthop Relat Res       Date:  2005-12       Impact factor: 4.176

5.  A multidisciplinary team approach to two-stage revision for the infected hip replacement: a minimum five-year follow-up study.

Authors:  M S Ibrahim; S Raja; M A Khan; F S Haddad
Journal:  Bone Joint J       Date:  2014-10       Impact factor: 5.082

6.  One-stage revision of infected hip arthroplasty: outcome of 39 consecutive hips.

Authors:  Thomas Ilchmann; Werner Zimmerli; Peter Emil Ochsner; Bernhard Kessler; Lukas Zwicky; Peter Graber; Martin Clauss
Journal:  Int Orthop       Date:  2015-07-30       Impact factor: 3.075

7.  Prolonged bacterial culture to identify late periprosthetic joint infection: a promising strategy.

Authors:  Peter Schäfer; Bernd Fink; Dieter Sandow; Andreas Margull; Irina Berger; Lars Frommelt
Journal:  Clin Infect Dis       Date:  2008-12-01       Impact factor: 9.079

8.  Cementless modular hip revision arthroplasty using the MRP Titan Revision Stem: outcome of 79 hips after an average of 4 years' follow-up.

Authors:  Alexander Schuh; Stefanie Werber; Ulrich Holzwarth; Günther Zeiler
Journal:  Arch Orthop Trauma Surg       Date:  2004-04-03       Impact factor: 3.067

9.  Medium-term follow-up of a modular tapered noncemented titanium stem in revision total hip arthroplasty: a single-surgeon experience.

Authors:  Wolfgang Klauser; Yannic Bangert; Philipp Lubinus; Daniel Kendoff
Journal:  J Arthroplasty       Date:  2012-10-22       Impact factor: 4.757

10.  Chronic infections in hip arthroplasties: comparing risk of reinfection following one-stage and two-stage revision: a systematic review and meta-analysis.

Authors:  Jeppe Lange; Anders Troelsen; Reimar W Thomsen; Kjeld Søballe
Journal:  Clin Epidemiol       Date:  2012-03-27       Impact factor: 4.790

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  2 in total

1.  Comparison of cementless and cemented cups in revision total hip arthroplasty using a computed tomography-based navigation system.

Authors:  Hiroaki Tagomori; Nobuhiro Kaku; Tomonori Tabata; Yuta Kubota; Hiroshi Tsumura
Journal:  J Clin Orthop Trauma       Date:  2019-05-28

Review 2.  The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium.

Authors:  Peter K Sculco; Timothy Wright; Michael-Alexander Malahias; Alexander Gu; Mathias Bostrom; Fares Haddad; Seth Jerabek; Michael Bolognesi; Thomas Fehring; Alejandro Gonzalez DellaValle; William Jiranek; William Walter; Wayne Paprosky; Donald Garbuz; Thomas Sculco
Journal:  HSS J       Date:  2021-09-28
  2 in total

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