Literature DB >> 2826818

Human papillomavirus type 16 open reading frame E7 encodes a transforming gene for rat 3Y1 cells.

T Kanda1, A Furuno, K Yoshiike.   

Abstract

Human papillomavirus type 16 (HPV 16) DNA is capable of morphologically transforming rat 3Y1 cells. The expression plasmids, constructed from the simian virus 40-based expression vector pSV2-0 and specific DNA fragments from the putative early region of the HPV 16 genome, were tested for their transforming capacity. Among the various pSV2 plasmids, only those containing the intact E7 coding region were found to produce foci of the transformed rat cells which could grow in a soft-agar medium. The data indicate that expression of the HPV 16 E7 open reading frame is sufficient to induce focal transformation of rat cells.

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Year:  1988        PMID： 2826818      PMCID： PMC250576          DOI： 10.1128/JVI.62.2.610-613.1988

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  37 in total

1.  RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination.

Authors:  H Lehrach; D Diamond; J M Wozney; H Boedtker
Journal:  Biochemistry       Date:  1977-10-18       Impact factor: 3.162

2.  A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors:  F L Graham; A J van der Eb
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

3.  In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA.

Authors:  D R Lowy; I Dvoretzky; R Shober; M F Law; L Engel; P M Howley
Journal:  Nature       Date:  1980-09-04       Impact factor: 49.962

4.  Alignment of the genome of monkey B-lymphotropic papovavirus to the genomes of simian virus 40 and BK virus.

Authors:  T Kanda; K Yoshiike; K K Takemoto
Journal:  J Virol       Date:  1983-04       Impact factor: 5.103

5.  Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

Authors:  P J Southern; P Berg
Journal:  J Mol Appl Genet       Date:  1982

6.  A quantitative in vitro focus assay for bovine papilloma virus.

Authors:  I Dvoretzky; R Shober; S K Chattopadhyay; D R Lowy
Journal:  Virology       Date:  1980-06       Impact factor: 3.616

7.  The primary structure and genetic organization of the bovine papillomavirus type 1 genome.

Authors:  E Y Chen; P M Howley; A D Levinson; P H Seeburg
Journal:  Nature       Date:  1982-10-07       Impact factor: 49.962

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences.

Authors:  M F Law; D R Lowy; I Dvoretzky; P M Howley
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

10.  Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.

Authors:  G Matlashewski; J Schneider; L Banks; N Jones; A Murray; L Crawford
Journal:  EMBO J       Date:  1987-06       Impact factor: 11.598
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  44 in total

1.  Use of a rapid, efficient inoculation method to induce papillomas by cottontail rabbit papillomavirus DNA shows that the E7 gene is required.

Authors:  J L Brandsma; Z H Yang; S W Barthold; E A Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

2.  Epithelial cells immortalized by human papillomaviruses have premalignant characteristics in organotypic culture.

Authors:  R A Blanton; N Perez-Reyes; D T Merrick; J K McDougall
Journal:  Am J Pathol       Date:  1991-03       Impact factor: 4.307

3.  Suppression in vivo of human papillomavirus type 18 E6-E7 gene expression in nontumorigenic HeLa X fibroblast hybrid cells.

Authors:  F X Bosch; E Schwarz; P Boukamp; N E Fusenig; D Bartsch; H zur Hausen
Journal:  J Virol       Date:  1990-10       Impact factor: 5.103

4.  Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18.

Authors:  J B Hudson; M A Bedell; D J McCance; L A Laiminis
Journal:  J Virol       Date:  1990-02       Impact factor: 5.103

5.  Mutational analysis of human papillomavirus type 16 E7 functions.

Authors:  S Watanabe; T Kanda; H Sato; A Furuno; K Yoshiike
Journal:  J Virol       Date:  1990-01       Impact factor: 5.103

6.  Sequence variation of human papillomavirus type 16 E7 in preinvasive and invasive cervical neoplasias.

Authors:  Y Fujinaga; K Okazawa; A Nishikawa; Y Yamakawa; M Fukushima; I Kato; K Fujinaga
Journal:  Virus Genes       Date:  1994-09       Impact factor: 2.332

7.  Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding.

Authors:  M C McIntyre; M G Frattini; S R Grossman; L A Laimins
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103

8.  The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells.

Authors:  C L Halbert; G W Demers; D A Galloway
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

9.  Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen.

Authors:  L P Chen; E K Thomas; S L Hu; I Hellström; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

10.  Progression of human papillomavirus type 18-immortalized human keratinocytes to a malignant phenotype.

Authors:  P J Hurlin; P Kaur; P P Smith; N Perez-Reyes; R A Blanton; J K McDougall
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-15       Impact factor: 11.205
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